JP5437660B2 - コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置 - Google Patents

コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置 Download PDF

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JP5437660B2
JP5437660B2 JP2009037150A JP2009037150A JP5437660B2 JP 5437660 B2 JP5437660 B2 JP 5437660B2 JP 2009037150 A JP2009037150 A JP 2009037150A JP 2009037150 A JP2009037150 A JP 2009037150A JP 5437660 B2 JP5437660 B2 JP 5437660B2
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coagulogen
lal
active substance
raw material
physiologically active
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JP2010190801A (ja
JP2010190801A5 (enExample
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克己 薮崎
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Kowa Co Ltd
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Kowa Co Ltd
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Priority to JP2009037150A priority Critical patent/JP5437660B2/ja
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Priority to CA2753062A priority patent/CA2753062A1/en
Priority to US13/202,285 priority patent/US8790885B2/en
Priority to PCT/JP2010/052551 priority patent/WO2010095718A1/ja
Priority to EP10743843A priority patent/EP2400302A4/en
Priority to KR1020117019609A priority patent/KR20110132334A/ko
Priority to CN2010800085809A priority patent/CN102326082A/zh
Publication of JP2010190801A publication Critical patent/JP2010190801A/ja
Publication of JP2010190801A5 publication Critical patent/JP2010190801A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2009037150A 2009-02-19 2009-02-19 コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置 Expired - Fee Related JP5437660B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2009037150A JP5437660B2 (ja) 2009-02-19 2009-02-19 コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置
US13/202,285 US8790885B2 (en) 2009-02-19 2010-02-19 Coagulogen raw material, process for producing the same, and method and apparatus for measuring physiologically active substance of biological origin using the same
PCT/JP2010/052551 WO2010095718A1 (ja) 2009-02-19 2010-02-19 コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置
EP10743843A EP2400302A4 (en) 2009-02-19 2010-02-19 COGULOGEN OUTPUT, METHOD OF MANUFACTURE AND METHOD AND DEVICE FOR MEASURING A BIOLOGICAL ACTIVE FROM AN ORGANISM THEREWITH
CA2753062A CA2753062A1 (en) 2009-02-19 2010-02-19 Coagulogen raw material, process for producing the same, and method and apparatus for measuring physiologically active substance of biological origin using the same
KR1020117019609A KR20110132334A (ko) 2009-02-19 2010-02-19 코아굴로겐 원료 및 그의 제조 방법, 그것을 이용한 생물 유래의 생리 활성 물질의 측정 방법 및 측정 장치
CN2010800085809A CN102326082A (zh) 2009-02-19 2010-02-19 凝固蛋白原原料及其制造方法、使用它测定来自生物的生理活性物质的方法和测定装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009037150A JP5437660B2 (ja) 2009-02-19 2009-02-19 コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置

Publications (3)

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JP2010190801A JP2010190801A (ja) 2010-09-02
JP2010190801A5 JP2010190801A5 (enExample) 2012-03-29
JP5437660B2 true JP5437660B2 (ja) 2014-03-12

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Country Status (7)

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US (1) US8790885B2 (enExample)
EP (1) EP2400302A4 (enExample)
JP (1) JP5437660B2 (enExample)
KR (1) KR20110132334A (enExample)
CN (1) CN102326082A (enExample)
CA (1) CA2753062A1 (enExample)
WO (1) WO2010095718A1 (enExample)

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* Cited by examiner, † Cited by third party
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US8507282B2 (en) * 2009-03-13 2013-08-13 Kowa Company, Ltd. Method for measuring physiologically active substance of biological origin, program for implementing the same, and apparatus for measuring physiologically active substance of biological origin
JP5981338B2 (ja) 2009-06-26 2016-08-31 チャールズ リバー ラボラトリーズ， インコーポレイテッド 加熱処理したリムルスアメーバ様細胞溶解物
CN103168243B (zh) * 2010-10-18 2016-03-02 小幡彻 凝胶粒子测定试剂及使用其的测定方法
WO2013062013A1 (ja) * 2011-10-26 2013-05-02 興和株式会社 生物由来の生理活性物質の測定方法及び、それに用いられる微粒子及び抽出液
DE102012110288A1 (de) * 2012-10-26 2014-04-30 Leibniz-Institut Für Neue Materialien Gemeinnützige Gmbh Verfahren zur Detektion von Endotoxinen und/oder 1,3-beta-D-Glucanen in einer Probe
WO2014199269A1 (en) 2013-06-12 2014-12-18 Kimberly-Clark Worldwide, Inc. Porous polyolefin fibers
CN106645721B (zh) * 2016-09-30 2018-10-09 广州鸿琪光学仪器科技有限公司 一种凝固酶检测试剂、反应垫、其制备方法及试剂盒
CN108956543B (zh) * 2017-05-18 2021-02-26 微采视像科技股份有限公司 凝血酶原时间的测定方法
WO2025181654A1 (en) * 2024-02-26 2025-09-04 Smith & Nephew, Inc. Methods for measurement of endotoxin contaminants in enzymatic compositions

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BE889407A (fr) * 1980-06-27 1981-10-16 Mallinckrodt Inc Amelioration du procede de preparation d'un lysat de limule
US4322217A (en) 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
DK255887D0 (da) 1987-05-20 1987-05-20 Claus Koch Immunoassay
JP2560139B2 (ja) * 1990-07-19 1996-12-04 マルハ株式会社 βーグルカン類に対する特異性の高いアメボサイト・ライセート及びその製造方法
JP2737514B2 (ja) 1992-01-24 1998-04-08 和光純薬工業株式会社 エンドトキシン測定用試料の前処理方法
JP3524120B2 (ja) * 1992-05-08 2004-05-10 生化学工業株式会社 前処理剤、前処理方法、前処理された試料による測定法、測定用キット及び試料の判定方法
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
JP3793573B2 (ja) * 1994-09-01 2006-07-05 生化学工業株式会社 （１→３）−β−Ｄ−グルカン結合性タンパク質、それを認識する抗体及びその利用
JPH10293129A (ja) 1997-04-18 1998-11-04 Nof Corp リン脂質中のエンドトキシン測定法
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US20120040385A1 (en) 2012-02-16
CA2753062A1 (en) 2010-08-26
JP2010190801A (ja) 2010-09-02
CN102326082A (zh) 2012-01-18
WO2010095718A1 (ja) 2010-08-26
EP2400302A4 (en) 2012-07-04
EP2400302A1 (en) 2011-12-28
KR20110132334A (ko) 2011-12-07
US8790885B2 (en) 2014-07-29

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