JP5399716B2 - アリール／アルキルビニルスルホンヒアルロン酸誘導体 - Google Patents
アリール／アルキルビニルスルホンヒアルロン酸誘導体 Download PDFInfo
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- JP5399716B2 JP5399716B2 JP2008556657A JP2008556657A JP5399716B2 JP 5399716 B2 JP5399716 B2 JP 5399716B2 JP 2008556657 A JP2008556657 A JP 2008556657A JP 2008556657 A JP2008556657 A JP 2008556657A JP 5399716 B2 JP5399716 B2 JP 5399716B2
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- Prior art keywords
- hyaluronic acid
- aryl
- alkyl
- acid derivative
- bacillus
- Prior art date
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- -1 Aryl / alkyl vinyl sulfone hyaluronic acid derivatives Chemical class 0.000 title claims description 30
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 126
- 229920002674 hyaluronan Polymers 0.000 claims description 101
- 229960003160 hyaluronic acid Drugs 0.000 claims description 82
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 24
- 125000003118 aryl group Chemical group 0.000 claims description 23
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- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Materials Engineering (AREA)
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- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Toxicology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| DKPA200600305 | 2006-03-02 | ||
| DKPA200600305 | 2006-03-02 | ||
| DKPA200600312 | 2006-03-03 | ||
| DKPA200600312 | 2006-03-03 | ||
| PCT/DK2007/000108 WO2007098770A1 (en) | 2006-03-02 | 2007-03-02 | Aryl/alkyl vinyl sulfone hyaluronic acid derivatives |
Publications (3)
| Publication Number | Publication Date |
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| JP2009528406A JP2009528406A (ja) | 2009-08-06 |
| JP2009528406A5 JP2009528406A5 (enExample) | 2010-04-02 |
| JP5399716B2 true JP5399716B2 (ja) | 2014-01-29 |
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| US (1) | US8071757B2 (enExample) |
| EP (1) | EP1994062B1 (enExample) |
| JP (1) | JP5399716B2 (enExample) |
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Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5758797B2 (ja) | 2008-04-04 | 2015-08-05 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法 |
| CN101870739B (zh) * | 2009-04-23 | 2015-07-22 | 华东理工大学 | 多粘类芽孢杆菌胞外多糖及其应用 |
| KR101551681B1 (ko) | 2009-07-30 | 2015-09-09 | 카르빌란 테라퓨틱스, 인코포레이티드 | 변형된 히알루론산 폴리머 조성물 및 관련방법 |
| JP6062917B2 (ja) | 2011-03-23 | 2017-01-18 | ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション | 泌尿器科の炎症の治療及び予防の方法 |
| ITMI20110644A1 (it) * | 2011-04-14 | 2012-10-15 | Giuliani Spa | Sistema per il rilascio prolungato di agenti cosmetici |
| JP5998201B2 (ja) * | 2011-04-20 | 2016-09-28 | カービラン セラピューティクス， インコーポレイテッド | Ｉｎ−ｓｉｔｕゲル形成組成物 |
| CZ2012842A3 (cs) * | 2012-11-27 | 2014-08-20 | Contipro Biotech S.R.O. | Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití |
| JP6800984B2 (ja) * | 2015-10-05 | 2020-12-16 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 軟骨傷害の検出及び処置のためのマイクロ並びにナノデバイス |
| WO2018053111A1 (en) | 2016-09-15 | 2018-03-22 | University Of Utah Research Foundation | In situ gelling compositions for the treatment or prevention of inflammation and tissue damage |
| JP2020532643A (ja) * | 2017-09-01 | 2020-11-12 | ピーエムアイディージー・エルエルシーＰｍｉｄｇ，Ｌｌｃ | 官能基化および架橋ポリマー |
| CN111228653A (zh) | 2018-11-13 | 2020-06-05 | 格莱科米拉治疗公司 | 用电离辐射加强癌症治疗的方法 |
| KR102441798B1 (ko) * | 2021-07-15 | 2022-09-08 | 아주대학교산학협력단 | 히알루론산 복합체를 포함하는 피부 질환 예방 또는 치료용 약학 조성물 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5128326A (en) * | 1984-12-06 | 1992-07-07 | Biomatrix, Inc. | Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same |
| JP2002516306A (ja) * | 1998-05-29 | 2002-06-04 | ボーン ケア インターナショナル インコーポレイテッド | ヒドロキシ−２５−エン−ビタミンｄ化合物の製造方法 |
| CA2550718C (en) * | 2003-12-30 | 2013-11-05 | Genzyme Corporation | Cohesive gels from cross-linked hyaluronan and/or hylan, their preparation and use |
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2007
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- 2007-03-02 AU AU2007219545A patent/AU2007219545B2/en not_active Ceased
- 2007-03-02 EP EP07702514A patent/EP1994062B1/en not_active Not-in-force
- 2007-03-02 WO PCT/DK2007/000108 patent/WO2007098770A1/en not_active Ceased
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- 2007-03-02 DK DK07702514T patent/DK1994062T3/da active
- 2007-03-02 US US12/161,717 patent/US8071757B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2643714C (en) | 2014-04-29 |
| CN101415732A (zh) | 2009-04-22 |
| AU2007219545B2 (en) | 2011-11-24 |
| JP2009528406A (ja) | 2009-08-06 |
| CA2643714A1 (en) | 2007-09-07 |
| ES2329731T3 (es) | 2009-11-30 |
| EP1994062B1 (en) | 2009-07-15 |
| US20110257123A1 (en) | 2011-10-20 |
| US8071757B2 (en) | 2011-12-06 |
| DE602007001593D1 (de) | 2009-08-27 |
| DK1994062T3 (da) | 2009-11-16 |
| EP1994062A1 (en) | 2008-11-26 |
| CN101415732B (zh) | 2011-10-12 |
| AU2007219545A1 (en) | 2007-09-07 |
| WO2007098770A1 (en) | 2007-09-07 |
| BRPI0708128A2 (pt) | 2011-05-17 |
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