AU2007219545B2 - Aryl/alkyl vinyl sulfone hyaluronic acid derivatives - Google Patents

Aryl/alkyl vinyl sulfone hyaluronic acid derivatives Download PDF

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Publication number
AU2007219545B2
AU2007219545B2 AU2007219545A AU2007219545A AU2007219545B2 AU 2007219545 B2 AU2007219545 B2 AU 2007219545B2 AU 2007219545 A AU2007219545 A AU 2007219545A AU 2007219545 A AU2007219545 A AU 2007219545A AU 2007219545 B2 AU2007219545 B2 AU 2007219545B2
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AU
Australia
Prior art keywords
hyaluronic acid
alkyl
aryl
group
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007219545A
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English (en)
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AU2007219545A1 (en
Inventor
Morten Wurtz Christensen
Corinne Eenschooten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes Biopharma DK AS
Original Assignee
Novozymes Biopharma DK AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of AU2007219545A1 publication Critical patent/AU2007219545A1/en
Assigned to NOVOZYMES BIOPHARMA DK A/S reassignment NOVOZYMES BIOPHARMA DK A/S Request for Assignment Assignors: NOVOZYMES BIOPOLYMER A/S
Application granted granted Critical
Publication of AU2007219545B2 publication Critical patent/AU2007219545B2/en
Ceased legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007219545A 2006-03-02 2007-03-02 Aryl/alkyl vinyl sulfone hyaluronic acid derivatives Ceased AU2007219545B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200600305 2006-03-02
DKPA200600305 2006-03-02
DKPA200600312 2006-03-03
DKPA200600312 2006-03-03
PCT/DK2007/000108 WO2007098770A1 (en) 2006-03-02 2007-03-02 Aryl/alkyl vinyl sulfone hyaluronic acid derivatives

Publications (2)

Publication Number Publication Date
AU2007219545A1 AU2007219545A1 (en) 2007-09-07
AU2007219545B2 true AU2007219545B2 (en) 2011-11-24

Family

ID=37983466

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007219545A Ceased AU2007219545B2 (en) 2006-03-02 2007-03-02 Aryl/alkyl vinyl sulfone hyaluronic acid derivatives

Country Status (11)

Country Link
US (1) US8071757B2 (enExample)
EP (1) EP1994062B1 (enExample)
JP (1) JP5399716B2 (enExample)
CN (1) CN101415732B (enExample)
AU (1) AU2007219545B2 (enExample)
BR (1) BRPI0708128A2 (enExample)
CA (1) CA2643714C (enExample)
DE (1) DE602007001593D1 (enExample)
DK (1) DK1994062T3 (enExample)
ES (1) ES2329731T3 (enExample)
WO (1) WO2007098770A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5758797B2 (ja) 2008-04-04 2015-08-05 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法
CN101870739B (zh) * 2009-04-23 2015-07-22 华东理工大学 多粘类芽孢杆菌胞外多糖及其应用
KR101551681B1 (ko) 2009-07-30 2015-09-09 카르빌란 테라퓨틱스, 인코포레이티드 변형된 히알루론산 폴리머 조성물 및 관련방법
JP6062917B2 (ja) 2011-03-23 2017-01-18 ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション 泌尿器科の炎症の治療及び予防の方法
ITMI20110644A1 (it) * 2011-04-14 2012-10-15 Giuliani Spa Sistema per il rilascio prolungato di agenti cosmetici
JP5998201B2 (ja) * 2011-04-20 2016-09-28 カービラン セラピューティクス， インコーポレイテッド Ｉｎ−ｓｉｔｕゲル形成組成物
CZ2012842A3 (cs) * 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
JP6800984B2 (ja) * 2015-10-05 2020-12-16 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 軟骨傷害の検出及び処置のためのマイクロ並びにナノデバイス
WO2018053111A1 (en) 2016-09-15 2018-03-22 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
JP2020532643A (ja) * 2017-09-01 2020-11-12 ピーエムアイディージー・エルエルシーＰｍｉｄｇ，Ｌｌｃ 官能基化および架橋ポリマー
CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
KR102441798B1 (ko) * 2021-07-15 2022-09-08 아주대학교산학협력단 히알루론산 복합체를 포함하는 피부 질환 예방 또는 치료용 약학 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128326A (en) * 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US6441207B1 (en) * 1998-05-29 2002-08-27 Bone Care International, Inc. Method for making hydroxy-25-ene-vitamin D compounds
WO2005066215A1 (en) * 2003-12-30 2005-07-21 Genzyme Corporation Cohesive gels form cross-linked hyaluronan and/or hylan, their preparation and use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128326A (en) * 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US6441207B1 (en) * 1998-05-29 2002-08-27 Bone Care International, Inc. Method for making hydroxy-25-ene-vitamin D compounds
WO2005066215A1 (en) * 2003-12-30 2005-07-21 Genzyme Corporation Cohesive gels form cross-linked hyaluronan and/or hylan, their preparation and use

Also Published As

Publication number Publication date
CA2643714C (en) 2014-04-29
CN101415732A (zh) 2009-04-22
JP2009528406A (ja) 2009-08-06
CA2643714A1 (en) 2007-09-07
JP5399716B2 (ja) 2014-01-29
ES2329731T3 (es) 2009-11-30
EP1994062B1 (en) 2009-07-15
US20110257123A1 (en) 2011-10-20
US8071757B2 (en) 2011-12-06
DE602007001593D1 (de) 2009-08-27
DK1994062T3 (da) 2009-11-16
EP1994062A1 (en) 2008-11-26
CN101415732B (zh) 2011-10-12
AU2007219545A1 (en) 2007-09-07
WO2007098770A1 (en) 2007-09-07
BRPI0708128A2 (pt) 2011-05-17

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PC1 Assignment before grant (sect. 113)

Owner name: NOVOZYMES BIOPHARMA DK A/S

Free format text: FORMER APPLICANT(S): NOVOZYMES BIOPOLYMER A/S

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired