JP5396279B2 - ＴＡＦＩａ阻害剤としての尿素及びスルファミド誘導体 - Google Patents

ＴＡＦＩａ阻害剤としての尿素及びスルファミド誘導体 Download PDF

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JP5396279B2
JP5396279B2 JP2009539631A JP2009539631A JP5396279B2 JP 5396279 B2 JP5396279 B2 JP 5396279B2 JP 2009539631 A JP2009539631 A JP 2009539631A JP 2009539631 A JP2009539631 A JP 2009539631A JP 5396279 B2 JP5396279 B2 JP 5396279B2
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alkylene
alkyl
amino
phenyl
cyclohexyl
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JP2010511641A5 (enExample
JP2010511641A (ja
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クリストファー・カルス
マーク・ブローエンシュトルプ
ヴェルンガルト・チェフティツキ
アンドレーアス・エヴェルス
マルクス・フォルマン
ニス・ハランド
ヘルマン・シュロイダー
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Sanofi SA
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
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AU2009310841A1 (en) * 2008-10-29 2010-05-06 Taisho Pharmaceutical Co., Ltd. Compounds having TAFIa inhibitory activity
RU2015156612A (ru) * 2013-06-10 2017-07-17 Санофи Макроциклические производные мочевины в качестве ингибиторов tafia, их получение и их применение в качестве фармацевтических средств
CN104529859B (zh) * 2015-01-13 2016-08-17 佛山市赛维斯医药科技有限公司 含苯胺和二烯氟代金刚烷结构的化合物、其制备方法和用途
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