JP2010511641A5 - - Google Patents

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Publication number
JP2010511641A5
JP2010511641A5 JP2009539631A JP2009539631A JP2010511641A5 JP 2010511641 A5 JP2010511641 A5 JP 2010511641A5 JP 2009539631 A JP2009539631 A JP 2009539631A JP 2009539631 A JP2009539631 A JP 2009539631A JP 2010511641 A5 JP2010511641 A5 JP 2010511641A5
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JP
Japan
Prior art keywords
alkylene
alkyl
phenyl
substituted
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009539631A
Other languages
English (en)
Japanese (ja)
Other versions
JP5396279B2 (ja
JP2010511641A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2007/010101 external-priority patent/WO2008067909A2/de
Publication of JP2010511641A publication Critical patent/JP2010511641A/ja
Publication of JP2010511641A5 publication Critical patent/JP2010511641A5/ja
Application granted granted Critical
Publication of JP5396279B2 publication Critical patent/JP5396279B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009539631A 2006-12-06 2007-11-22 ＴＡＦＩａ阻害剤としての尿素及びスルファミド誘導体 Expired - Fee Related JP5396279B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006057413 2006-12-06
DE102006057413.3 2006-12-06
PCT/EP2007/010101 WO2008067909A2 (de) 2006-12-06 2007-11-22 Harnstoff- und sulfamidderivate als inhibitoren von tafia

Publications (3)

Publication Number Publication Date
JP2010511641A JP2010511641A (ja) 2010-04-15
JP2010511641A5 true JP2010511641A5 (enExample) 2010-12-16
JP5396279B2 JP5396279B2 (ja) 2014-01-22

Family

ID=39384480

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009539631A Expired - Fee Related JP5396279B2 (ja) 2006-12-06 2007-11-22 ＴＡＦＩａ阻害剤としての尿素及びスルファミド誘導体

Country Status (27)

Country Link
US (1) US8389764B2 (enExample)
EP (1) EP2104497B1 (enExample)
JP (1) JP5396279B2 (enExample)
KR (1) KR20090087044A (enExample)
CN (1) CN101553219B (enExample)
AR (1) AR064119A1 (enExample)
AU (1) AU2007327959B2 (enExample)
BR (1) BRPI0720241A2 (enExample)
CA (1) CA2671861C (enExample)
CL (1) CL2007003494A1 (enExample)
CO (1) CO6180422A2 (enExample)
CY (1) CY1116384T1 (enExample)
DK (1) DK2104497T3 (enExample)
ES (1) ES2537093T3 (enExample)
HR (1) HRP20150514T1 (enExample)
MA (1) MA30968B1 (enExample)
MX (1) MX2009005516A (enExample)
NO (1) NO20092246L (enExample)
NZ (1) NZ577312A (enExample)
PE (1) PE20081349A1 (enExample)
PL (1) PL2104497T3 (enExample)
PT (1) PT2104497E (enExample)
RU (1) RU2459619C2 (enExample)
SI (1) SI2104497T1 (enExample)
TW (1) TWI399203B (enExample)
WO (1) WO2008067909A2 (enExample)
ZA (1) ZA200903040B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101673886B1 (ko) 2008-06-06 2016-11-08 사노피 ＴＡＦＩａ의 억제제로서의 마크로사이클릭 우레아 및 술파미드 유도체
AR072278A1 (es) 2008-06-23 2010-08-18 Astrazeneca Ab Compuestos inhibidores de trombina
US8354444B2 (en) 2008-09-18 2013-01-15 Hoffmann-La Roche Inc. Substituted pyrrolidine-2-carboxamides
NZ592764A (en) * 2008-10-29 2012-08-31 Taisho Pharmaceutical Co Ltd Compound having tafia inhibitory activity
JP6461113B2 (ja) 2013-06-10 2019-01-30 サノフイＳａｎｏｆｉ ＴＡＦＩａの阻害剤としての大環状尿素誘導体、それらの製造および医薬としての使用
CN104529859B (zh) * 2015-01-13 2016-08-17 佛山市赛维斯医药科技有限公司 含苯胺和二烯氟代金刚烷结构的化合物、其制备方法和用途
RU2687254C1 (ru) * 2018-10-03 2019-05-08 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) N-гетероциклические производные борниламина в качестве ингибиторов ортопоксвирусов

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU667995B2 (en) * 1993-02-15 1996-04-18 Bayer Aktiengesellschaft New pseudopeptides having an antiviral action
TW394760B (en) * 1993-09-07 2000-06-21 Hoffmann La Roche Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same
DE69824433D1 (en) * 1997-08-28 2004-07-15 Biovitrum Ab Proteintyrosinphosphatase inhibitoren
US6482921B1 (en) * 1999-01-28 2002-11-19 Essential Therapeutics, Inc. Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use
CA2362705A1 (en) * 1999-03-19 2000-09-28 Joseph B. Santella, Iii N-adamant-1-yl-n'-¬4-chlorobenzothiazol-2-yl| urea useful in the treatment of inflammation and as an anticancer radiosensitizing agent
US6359129B1 (en) * 2000-08-15 2002-03-19 University Of Kansas Amino acid-derived, 7-membered cyclic sulfamides and methods of synthesizing the same
SI1311488T1 (sl) * 2000-08-17 2010-01-29 Pfizer Ltd Substituirani imidazoli kot inhibitorji TAFIA
DE102004020186A1 (de) 2004-04-22 2005-11-17 Aventis Pharma Deutschland Gmbh Heterocyclylessigsäuren als Inhibitoren von TAFla
US20060105995A1 (en) * 2004-10-05 2006-05-18 Schering Aktiengesellschaft TAFI inhibitors and their use to treat pulmonary fibrosis

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