JP5323354B2 - 多目的生体材料組成物 - Google Patents
多目的生体材料組成物 Download PDFInfo
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- JP5323354B2 JP5323354B2 JP2007532675A JP2007532675A JP5323354B2 JP 5323354 B2 JP5323354 B2 JP 5323354B2 JP 2007532675 A JP2007532675 A JP 2007532675A JP 2007532675 A JP2007532675 A JP 2007532675A JP 5323354 B2 JP5323354 B2 JP 5323354B2
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- JP
- Japan
- Prior art keywords
- bone
- sugar
- composition according
- calcium
- biomaterial composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229910052791 calcium Inorganic materials 0.000 claims abstract description 40
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- 239000011787 zinc oxide Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
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- Transplantation (AREA)
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- Surgery (AREA)
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- Materials Engineering (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/US2005/034035 WO2006034420A2 (en) | 2004-09-21 | 2005-09-21 | Multi-purpose bio-material composition |
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| JP2008513161A JP2008513161A (ja) | 2008-05-01 |
| JP2008513161A5 JP2008513161A5 (enExample) | 2008-11-20 |
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| PT1773816E (pt) | 2004-06-24 | 2015-04-29 | Vertex Pharma | Moduladores de transportadores de cassete de ligação de atp |
| US9078884B2 (en) | 2004-09-21 | 2015-07-14 | Thomas Joseph Lally | Bio-material composition and method for spinal fusion |
| RS55940B1 (sr) | 2005-12-28 | 2017-09-29 | Vertex Pharma | Čvrsti oblici n-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksohinolin-3-karboksamida |
| US20070160845A1 (en) * | 2006-01-09 | 2007-07-12 | Siemens Aktiengesellschaft | Electrical device with flame retardant coating and manufacturing method therefor |
| US20100092573A1 (en) * | 2007-03-12 | 2010-04-15 | Thomas Lally | Hemostatic bio-material composition and method |
| JP4914308B2 (ja) * | 2007-08-14 | 2012-04-11 | 瑞安大藥廠股▲分▼有限公司 | 生分解可能性を有する骨折治療用セメント及びその製造方法 |
| KR100957543B1 (ko) * | 2008-01-28 | 2010-05-11 | 연세대학교 산학협력단 | 비정질 칼슘 포스페이트를 함유하는 골대체용 조성물 |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US8668697B2 (en) | 2009-10-07 | 2014-03-11 | Abyrx, Inc. | Methods and devices for sternal closure |
| US8337497B2 (en) * | 2009-10-07 | 2012-12-25 | Doctors Research Group, Inc. | Methods for sternal closure |
| JP5095034B2 (ja) | 2009-12-18 | 2012-12-12 | ハウメディカ・オステオニクス・コーポレイション | 照射後貯蔵安定性の直接注入可能なデュアルペースト型骨セメントを製造するシステムおよびリン酸カルシウム組成物 |
| US8926710B2 (en) * | 2010-10-25 | 2015-01-06 | Warsaw Orthopedic, Inc. | Osteoinductive bone graft injectable cement |
| WO2012062360A1 (en) | 2010-11-10 | 2012-05-18 | Stryker Trauma Gmbh | Polymeric bone foam composition and method |
| MX2014010253A (es) * | 2012-02-27 | 2014-11-12 | Vertex Pharma | Composicion farmaceutica y administraciones de la misma. |
| CN103407980B (zh) * | 2013-07-16 | 2015-06-24 | 西安理工大学 | 磷酸镁医用骨粘结剂的制备方法 |
| CN103800944B (zh) * | 2014-02-24 | 2015-11-25 | 李陵江 | 一种植骨填充材料及其制备方法 |
| CN106061520A (zh) * | 2014-03-03 | 2016-10-26 | 医乐世医疗技术蒂默什达拉公司 | 用于刺激骨形成的复合物 |
| US10238507B2 (en) | 2015-01-12 | 2019-03-26 | Surgentec, Llc | Bone graft delivery system and method for using same |
| CN105944148A (zh) * | 2016-04-29 | 2016-09-21 | 苏州蔻美新材料有限公司 | 一种骨填充材料的制备方法 |
| US20180326124A1 (en) * | 2017-05-12 | 2018-11-15 | Bone Solutions, Inc. | Bio-Material Composition and Methods of Use |
| US10687828B2 (en) | 2018-04-13 | 2020-06-23 | Surgentec, Llc | Bone graft delivery system and method for using same |
| US11116647B2 (en) | 2018-04-13 | 2021-09-14 | Surgentec, Llc | Bone graft delivery system and method for using same |
| RU2695342C1 (ru) * | 2018-04-19 | 2019-07-23 | Общество с ограниченной ответственностью "ГИСТОГРАФТ" | Способ получения керамических гранул для регенерации костной ткани |
| JP2023528411A (ja) * | 2020-06-01 | 2023-07-04 | ボーン ソリューションズ， インコーポレイテッド | 頭蓋顎顔面手術における生体材料組成物及びその使用方法 |
| US12343444B2 (en) | 2021-08-16 | 2025-07-01 | Bone Solutions, Inc. | Structural implant to prevent bone defects |
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| DE2756256A1 (de) * | 1977-12-16 | 1979-06-21 | Scheicher Hans | Hilfsmittel zum bedecken und/oder ausfuellen von knochendefekten und verfahren zur herstellung desselben |
| US5129905A (en) * | 1988-04-20 | 1992-07-14 | Norian Corporation | Methods for in situ prepared calcium phosphate minerals |
| JPH03191963A (ja) * | 1989-12-22 | 1991-08-21 | Mitsubishi Materials Corp | リン酸カルシウム質多孔体骨補填材 |
| US6027742A (en) * | 1995-05-19 | 2000-02-22 | Etex Corporation | Bioresorbable ceramic composites |
| CA2172917A1 (en) * | 1995-06-07 | 1996-12-08 | Hugh R. Mcmullin | Moldable collagen compositions for hard tissue repair and augmentation |
| AU729086C (en) * | 1996-03-05 | 2006-12-14 | Depuy Acromed, Inc. | Method of promoting bone growth with hyaluronic acid and growth factors |
| DE19713229A1 (de) | 1997-04-01 | 1998-10-08 | Merck Patent Gmbh | Antibiotikumhaltige Knochenzementpaste |
| US5968999A (en) * | 1997-10-28 | 1999-10-19 | Charlotte-Mecklenburg Hospital Authority | Bone cement compositions |
| RU2132702C1 (ru) * | 1997-12-26 | 1999-07-10 | Елагина Ирина Алексеевна | Остеопластический стеклокристаллический композиционный материал для изготовления пористых имплантатов в виде гранул и способ их получения |
| EP1235599B1 (en) * | 1999-12-09 | 2003-07-23 | Dr.h.c. Robert Mathys Stiftung | Brushite hydraulic cement stabilized with a magnesium salt |
| EP1255576B1 (en) * | 1999-12-09 | 2003-08-20 | Biosyntech Canada Inc. | Mineral-polymer hybrid composition |
| US6375935B1 (en) * | 2000-04-28 | 2002-04-23 | Brent R. Constantz | Calcium phosphate cements prepared from silicate solutions |
| US6533821B1 (en) * | 2000-06-22 | 2003-03-18 | Thomas Lally | Bio-adhesive composition, method for adhering objects to bone |
| AU2001271491A1 (en) | 2000-06-26 | 2002-01-08 | Monsanto Technology Llc | Non-aqueous surfactant-containing formulations for extended release of somatotropin |
| US8029755B2 (en) * | 2003-08-06 | 2011-10-04 | Angstrom Medica | Tricalcium phosphates, their composites, implants incorporating them, and method for their production |
| US7527098B2 (en) * | 2004-05-27 | 2009-05-05 | Halliburton Energy Services, Inc. | Methods of increasing the thickening times of phosphate-based cementitious compositions in high-temperature wellbores |
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- 2005-09-21 RU RU2007115046/15A patent/RU2389495C2/ru not_active IP Right Cessation
- 2005-09-21 EP EP05798295.1A patent/EP1804814B1/en not_active Expired - Lifetime
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- 2005-09-21 BR BRPI0515527-4A patent/BRPI0515527A/pt not_active IP Right Cessation
- 2005-09-21 WO PCT/US2005/034035 patent/WO2006034420A2/en not_active Ceased
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- 2005-09-21 AU AU2005286719A patent/AU2005286719B2/en not_active Ceased
- 2005-09-21 CN CN2005800318155A patent/CN101076344B/zh not_active Expired - Lifetime
- 2005-09-21 CA CA2580948A patent/CA2580948C/en not_active Expired - Lifetime
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| HK1106719A1 (en) | 2008-03-20 |
| KR101420100B1 (ko) | 2014-07-30 |
| MX2007003099A (es) | 2007-08-14 |
| AU2005286719B2 (en) | 2011-03-24 |
| RU2007115046A (ru) | 2008-10-27 |
| JP2008513161A (ja) | 2008-05-01 |
| KR20070054254A (ko) | 2007-05-28 |
| CA2580948C (en) | 2014-09-09 |
| BRPI0515527A (pt) | 2008-07-29 |
| CN101076344B (zh) | 2011-07-13 |
| WO2006034420A3 (en) | 2007-07-26 |
| CA2580948A1 (en) | 2006-03-30 |
| CN101076344A (zh) | 2007-11-21 |
| AU2005286719A1 (en) | 2006-03-30 |
| US20070218144A1 (en) | 2007-09-20 |
| EP1804814A2 (en) | 2007-07-11 |
| RU2389495C2 (ru) | 2010-05-20 |
| EP1804814B1 (en) | 2013-12-11 |
| EP1804814A4 (en) | 2010-02-24 |
| WO2006034420A2 (en) | 2006-03-30 |
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