CN101076344B - 多用途生物材料组合物 - Google Patents

多用途生物材料组合物 Download PDF

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Publication number
CN101076344B
CN101076344B CN2005800318155A CN200580031815A CN101076344B CN 101076344 B CN101076344 B CN 101076344B CN 2005800318155 A CN2005800318155 A CN 2005800318155A CN 200580031815 A CN200580031815 A CN 200580031815A CN 101076344 B CN101076344 B CN 101076344B
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CN
China
Prior art keywords
bone
calcium
sugar
biomaterial
composition
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Expired - Lifetime
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CN2005800318155A
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English (en)
Chinese (zh)
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CN101076344A (zh
Inventor
T·J·拉利
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Bone Solutions Inc
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Individual
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Publication of CN101076344A publication Critical patent/CN101076344A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
CN2005800318155A 2004-09-21 2005-09-21 多用途生物材料组合物 Expired - Lifetime CN101076344B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61184004P 2004-09-21 2004-09-21
US60/611,840 2004-09-21
PCT/US2005/034035 WO2006034420A2 (en) 2004-09-21 2005-09-21 Multi-purpose bio-material composition

Publications (2)

Publication Number Publication Date
CN101076344A CN101076344A (zh) 2007-11-21
CN101076344B true CN101076344B (zh) 2011-07-13

Family

ID=36090684

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800318155A Expired - Lifetime CN101076344B (zh) 2004-09-21 2005-09-21 多用途生物材料组合物

Country Status (11)

Country Link
US (1) US20070218144A1 (enExample)
EP (1) EP1804814B1 (enExample)
JP (1) JP5323354B2 (enExample)
KR (1) KR101420100B1 (enExample)
CN (1) CN101076344B (enExample)
AU (1) AU2005286719B2 (enExample)
BR (1) BRPI0515527A (enExample)
CA (1) CA2580948C (enExample)
MX (1) MX2007003099A (enExample)
RU (1) RU2389495C2 (enExample)
WO (1) WO2006034420A2 (enExample)

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NZ587549A (en) 2004-06-24 2012-10-26 Vertex Pharma 6-Amino-indole derivatives and processes for their preparation
US9078884B2 (en) 2004-09-21 2015-07-14 Thomas Joseph Lally Bio-material composition and method for spinal fusion
CA2635581C (en) 2005-12-28 2017-02-28 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US20070160845A1 (en) * 2006-01-09 2007-07-12 Siemens Aktiengesellschaft Electrical device with flame retardant coating and manufacturing method therefor
US20100092573A1 (en) * 2007-03-12 2010-04-15 Thomas Lally Hemostatic bio-material composition and method
JP4914308B2 (ja) * 2007-08-14 2012-04-11 瑞安大藥廠股▲分▼有限公司 生分解可能性を有する骨折治療用セメント及びその製造方法
KR100957543B1 (ko) * 2008-01-28 2010-05-11 연세대학교 산학협력단 비정질 칼슘 포스페이트를 함유하는 골대체용 조성물
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US8668697B2 (en) 2009-10-07 2014-03-11 Abyrx, Inc. Methods and devices for sternal closure
US8337497B2 (en) * 2009-10-07 2012-12-25 Doctors Research Group, Inc. Methods for sternal closure
EP2512537B1 (en) * 2009-12-18 2015-08-26 Howmedica Osteonics Corp. Dual paste direct injectable bone cement precursor systems and methods of making same
US8926710B2 (en) 2010-10-25 2015-01-06 Warsaw Orthopedic, Inc. Osteoinductive bone graft injectable cement
EP2637983B1 (en) 2010-11-10 2018-12-26 Stryker European Holdings I, LLC Process for the preparation of a polymeric bone foam
AU2013226076B2 (en) 2012-02-27 2017-11-16 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administration thereof
CN103407980B (zh) * 2013-07-16 2015-06-24 西安理工大学 磷酸镁医用骨粘结剂的制备方法
CN103800944B (zh) * 2014-02-24 2015-11-25 李陵江 一种植骨填充材料及其制备方法
EP3113805A4 (en) * 2014-03-03 2017-11-22 Elos Medtech Timmersdala AB Compound for stimulating bone formation
US10238507B2 (en) 2015-01-12 2019-03-26 Surgentec, Llc Bone graft delivery system and method for using same
CN105944148A (zh) * 2016-04-29 2016-09-21 苏州蔻美新材料有限公司 一种骨填充材料的制备方法
WO2018209337A1 (en) * 2017-05-12 2018-11-15 Bones Solutions, Inc. Bio-material composition and methods of use
US11116647B2 (en) 2018-04-13 2021-09-14 Surgentec, Llc Bone graft delivery system and method for using same
US10687828B2 (en) 2018-04-13 2020-06-23 Surgentec, Llc Bone graft delivery system and method for using same
RU2695342C1 (ru) * 2018-04-19 2019-07-23 Общество с ограниченной ответственностью "ГИСТОГРАФТ" Способ получения керамических гранул для регенерации костной ткани
CA3178495A1 (en) * 2020-06-01 2021-12-09 Bone Solutions, Inc. Bio-material composition and methods of use in craniomaxillofacial surgery
US12343444B2 (en) 2021-08-16 2025-07-01 Bone Solutions, Inc. Structural implant to prevent bone defects

Citations (1)

* Cited by examiner, † Cited by third party
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US6733582B1 (en) * 1999-12-09 2004-05-11 Dr. H. C. Robert Mathys Stiftung Brushite hydraulic cement stabilized with a magnesium salt

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DE2756256A1 (de) * 1977-12-16 1979-06-21 Scheicher Hans Hilfsmittel zum bedecken und/oder ausfuellen von knochendefekten und verfahren zur herstellung desselben
US5129905A (en) * 1988-04-20 1992-07-14 Norian Corporation Methods for in situ prepared calcium phosphate minerals
JPH03191963A (ja) * 1989-12-22 1991-08-21 Mitsubishi Materials Corp リン酸カルシウム質多孔体骨補填材
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
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US5942499A (en) * 1996-03-05 1999-08-24 Orquest, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
DE19713229A1 (de) 1997-04-01 1998-10-08 Merck Patent Gmbh Antibiotikumhaltige Knochenzementpaste
US5968999A (en) * 1997-10-28 1999-10-19 Charlotte-Mecklenburg Hospital Authority Bone cement compositions
RU2132702C1 (ru) * 1997-12-26 1999-07-10 Елагина Ирина Алексеевна Остеопластический стеклокристаллический композиционный материал для изготовления пористых имплантатов в виде гранул и способ их получения
EP1255576B1 (en) * 1999-12-09 2003-08-20 Biosyntech Canada Inc. Mineral-polymer hybrid composition
US6375935B1 (en) * 2000-04-28 2002-04-23 Brent R. Constantz Calcium phosphate cements prepared from silicate solutions
US6533821B1 (en) * 2000-06-22 2003-03-18 Thomas Lally Bio-adhesive composition, method for adhering objects to bone
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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6733582B1 (en) * 1999-12-09 2004-05-11 Dr. H. C. Robert Mathys Stiftung Brushite hydraulic cement stabilized with a magnesium salt

Also Published As

Publication number Publication date
WO2006034420A2 (en) 2006-03-30
CA2580948A1 (en) 2006-03-30
EP1804814B1 (en) 2013-12-11
EP1804814A2 (en) 2007-07-11
KR101420100B1 (ko) 2014-07-30
AU2005286719B2 (en) 2011-03-24
HK1106719A1 (en) 2008-03-20
RU2389495C2 (ru) 2010-05-20
MX2007003099A (es) 2007-08-14
WO2006034420A3 (en) 2007-07-26
CA2580948C (en) 2014-09-09
BRPI0515527A (pt) 2008-07-29
KR20070054254A (ko) 2007-05-28
US20070218144A1 (en) 2007-09-20
AU2005286719A1 (en) 2006-03-30
JP2008513161A (ja) 2008-05-01
JP5323354B2 (ja) 2013-10-23
RU2007115046A (ru) 2008-10-27
EP1804814A4 (en) 2010-02-24
CN101076344A (zh) 2007-11-21

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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20160720

Address after: Texas, USA

Patentee after: Bone solutions, Limited by Share Ltd.

Address before: Illinois, USA

Patentee before: Lally Thomas Joseph

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20110713