KR101420100B1 - 다목적 생체재료 조성물 - Google Patents

다목적 생체재료 조성물 Download PDF

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Publication number
KR101420100B1
KR101420100B1 KR1020077008999A KR20077008999A KR101420100B1 KR 101420100 B1 KR101420100 B1 KR 101420100B1 KR 1020077008999 A KR1020077008999 A KR 1020077008999A KR 20077008999 A KR20077008999 A KR 20077008999A KR 101420100 B1 KR101420100 B1 KR 101420100B1
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South Korea
Prior art keywords
phosphate
calcium
dry weight
present
bone
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Expired - Fee Related
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KR1020077008999A
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English (en)
Korean (ko)
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KR20070054254A (ko
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토마스 죠셉 랠리
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토마스 죠셉 랠리
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
KR1020077008999A 2004-09-21 2005-09-21 다목적 생체재료 조성물 Expired - Fee Related KR101420100B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61184004P 2004-09-21 2004-09-21
US60/611,840 2004-09-21
PCT/US2005/034035 WO2006034420A2 (en) 2004-09-21 2005-09-21 Multi-purpose bio-material composition

Publications (2)

Publication Number Publication Date
KR20070054254A KR20070054254A (ko) 2007-05-28
KR101420100B1 true KR101420100B1 (ko) 2014-07-30

Family

ID=36090684

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077008999A Expired - Fee Related KR101420100B1 (ko) 2004-09-21 2005-09-21 다목적 생체재료 조성물

Country Status (11)

Country Link
US (1) US20070218144A1 (enExample)
EP (1) EP1804814B1 (enExample)
JP (1) JP5323354B2 (enExample)
KR (1) KR101420100B1 (enExample)
CN (1) CN101076344B (enExample)
AU (1) AU2005286719B2 (enExample)
BR (1) BRPI0515527A (enExample)
CA (1) CA2580948C (enExample)
MX (1) MX2007003099A (enExample)
RU (1) RU2389495C2 (enExample)
WO (1) WO2006034420A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
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HUE032540T2 (en) 2004-06-24 2017-09-28 Vertex Pharma Modulators of ATP-binding cassette transporters
US9078884B2 (en) 2004-09-21 2015-07-14 Thomas Joseph Lally Bio-material composition and method for spinal fusion
CA2635581C (en) 2005-12-28 2017-02-28 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US20070160845A1 (en) * 2006-01-09 2007-07-12 Siemens Aktiengesellschaft Electrical device with flame retardant coating and manufacturing method therefor
US20100092573A1 (en) * 2007-03-12 2010-04-15 Thomas Lally Hemostatic bio-material composition and method
JP4914308B2 (ja) * 2007-08-14 2012-04-11 瑞安大藥廠股▲分▼有限公司 生分解可能性を有する骨折治療用セメント及びその製造方法
KR100957543B1 (ko) * 2008-01-28 2010-05-11 연세대학교 산학협력단 비정질 칼슘 포스페이트를 함유하는 골대체용 조성물
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US8668697B2 (en) 2009-10-07 2014-03-11 Abyrx, Inc. Methods and devices for sternal closure
US8337497B2 (en) * 2009-10-07 2012-12-25 Doctors Research Group, Inc. Methods for sternal closure
US8481065B2 (en) * 2009-12-18 2013-07-09 Howmedica Osteonics Corp. Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
US8926710B2 (en) * 2010-10-25 2015-01-06 Warsaw Orthopedic, Inc. Osteoinductive bone graft injectable cement
US10182973B2 (en) 2010-11-10 2019-01-22 Stryker European Holdings I, Llc Polymeric bone foam composition and method
RU2692779C2 (ru) 2012-02-27 2019-06-27 Вертекс Фармасьютикалз Инкорпорейтед Фармацевтическая композиция и ее введения
CN103407980B (zh) * 2013-07-16 2015-06-24 西安理工大学 磷酸镁医用骨粘结剂的制备方法
CN103800944B (zh) * 2014-02-24 2015-11-25 李陵江 一种植骨填充材料及其制备方法
CN106061520A (zh) * 2014-03-03 2016-10-26 医乐世医疗技术蒂默什达拉公司 用于刺激骨形成的复合物
US10238507B2 (en) 2015-01-12 2019-03-26 Surgentec, Llc Bone graft delivery system and method for using same
CN105944148A (zh) * 2016-04-29 2016-09-21 苏州蔻美新材料有限公司 一种骨填充材料的制备方法
WO2018209337A1 (en) * 2017-05-12 2018-11-15 Bones Solutions, Inc. Bio-material composition and methods of use
US11116647B2 (en) 2018-04-13 2021-09-14 Surgentec, Llc Bone graft delivery system and method for using same
US10687828B2 (en) 2018-04-13 2020-06-23 Surgentec, Llc Bone graft delivery system and method for using same
RU2695342C1 (ru) * 2018-04-19 2019-07-23 Общество с ограниченной ответственностью "ГИСТОГРАФТ" Способ получения керамических гранул для регенерации костной ткани
CA3178495A1 (en) * 2020-06-01 2021-12-09 Bone Solutions, Inc. Bio-material composition and methods of use in craniomaxillofacial surgery
US12343444B2 (en) 2021-08-16 2025-07-01 Bone Solutions, Inc. Structural implant to prevent bone defects

Citations (2)

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Publication number Priority date Publication date Assignee Title
US5942499A (en) * 1996-03-05 1999-08-24 Orquest, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
WO2001097679A2 (en) * 2000-06-22 2001-12-27 Thomas Joseph Lally Bio-adhesive composition, method for adhering objects to bone

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DE2756256A1 (de) * 1977-12-16 1979-06-21 Scheicher Hans Hilfsmittel zum bedecken und/oder ausfuellen von knochendefekten und verfahren zur herstellung desselben
US5129905A (en) * 1988-04-20 1992-07-14 Norian Corporation Methods for in situ prepared calcium phosphate minerals
JPH03191963A (ja) * 1989-12-22 1991-08-21 Mitsubishi Materials Corp リン酸カルシウム質多孔体骨補填材
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
CA2172917A1 (en) * 1995-06-07 1996-12-08 Hugh R. Mcmullin Moldable collagen compositions for hard tissue repair and augmentation
DE19713229A1 (de) 1997-04-01 1998-10-08 Merck Patent Gmbh Antibiotikumhaltige Knochenzementpaste
US5968999A (en) * 1997-10-28 1999-10-19 Charlotte-Mecklenburg Hospital Authority Bone cement compositions
RU2132702C1 (ru) * 1997-12-26 1999-07-10 Елагина Ирина Алексеевна Остеопластический стеклокристаллический композиционный материал для изготовления пористых имплантатов в виде гранул и способ их получения
WO2001041824A1 (en) * 1999-12-09 2001-06-14 Dr.H.C. Robert Mathys Stiftung Brushite hydraulic cement stabilized with a magnesium salt
EP1237585B1 (en) * 1999-12-09 2003-06-18 Biosyntech Canada Inc. Mineral-polymer hybrid composition
US6375935B1 (en) * 2000-04-28 2002-04-23 Brent R. Constantz Calcium phosphate cements prepared from silicate solutions
MXPA03000073A (es) 2000-06-26 2003-09-25 Monsanto Technology Llc Formulaciones que contienen agente tensioactivo no acuoso para la liberacion prolongada de somatrotopina.
US8029755B2 (en) * 2003-08-06 2011-10-04 Angstrom Medica Tricalcium phosphates, their composites, implants incorporating them, and method for their production
US7527098B2 (en) * 2004-05-27 2009-05-05 Halliburton Energy Services, Inc. Methods of increasing the thickening times of phosphate-based cementitious compositions in high-temperature wellbores

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
US5942499A (en) * 1996-03-05 1999-08-24 Orquest, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
WO2001097679A2 (en) * 2000-06-22 2001-12-27 Thomas Joseph Lally Bio-adhesive composition, method for adhering objects to bone

Also Published As

Publication number Publication date
AU2005286719B2 (en) 2011-03-24
AU2005286719A1 (en) 2006-03-30
CA2580948A1 (en) 2006-03-30
JP2008513161A (ja) 2008-05-01
WO2006034420A2 (en) 2006-03-30
KR20070054254A (ko) 2007-05-28
RU2389495C2 (ru) 2010-05-20
RU2007115046A (ru) 2008-10-27
EP1804814B1 (en) 2013-12-11
BRPI0515527A (pt) 2008-07-29
MX2007003099A (es) 2007-08-14
US20070218144A1 (en) 2007-09-20
CA2580948C (en) 2014-09-09
EP1804814A4 (en) 2010-02-24
EP1804814A2 (en) 2007-07-11
JP5323354B2 (ja) 2013-10-23
CN101076344A (zh) 2007-11-21
CN101076344B (zh) 2011-07-13
HK1106719A1 (en) 2008-03-20
WO2006034420A3 (en) 2007-07-26

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