JP5227487B2 - 移植可能なプロテーゼ用の生体溶解吸収性組成物 - Google Patents

移植可能なプロテーゼ用の生体溶解吸収性組成物 Download PDF

Info

Publication number
JP5227487B2
JP5227487B2 JP2000509454A JP2000509454A JP5227487B2 JP 5227487 B2 JP5227487 B2 JP 5227487B2 JP 2000509454 A JP2000509454 A JP 2000509454A JP 2000509454 A JP2000509454 A JP 2000509454A JP 5227487 B2 JP5227487 B2 JP 5227487B2
Authority
JP
Japan
Prior art keywords
composition
biodissolvable
water
copolymer
hydrogel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000509454A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001514931A5 (enExample
JP2001514931A (ja
Inventor
ゲアリー エル ルーミス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Publication of JP2001514931A publication Critical patent/JP2001514931A/ja
Publication of JP2001514931A5 publication Critical patent/JP2001514931A5/ja
Application granted granted Critical
Publication of JP5227487B2 publication Critical patent/JP5227487B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G64/00Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
    • C08G64/18Block or graft polymers
    • C08G64/183Block or graft polymers containing polyether sequences
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66Polyesters containing oxygen in the form of ether groups
    • C08G63/664Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66Polyesters containing oxygen in the form of ether groups
    • C08G63/668Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/676Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/408Virucides, spermicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924Material characteristic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000509454A 1997-08-18 1998-08-14 移植可能なプロテーゼ用の生体溶解吸収性組成物 Expired - Fee Related JP5227487B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/914,130 1997-08-18
US08/914,130 US5854382A (en) 1997-08-18 1997-08-18 Bioresorbable compositions for implantable prostheses
PCT/US1998/016933 WO1999008718A2 (en) 1997-08-18 1998-08-14 Bioresorbable compositions for implantable prostheses

Publications (3)

Publication Number Publication Date
JP2001514931A JP2001514931A (ja) 2001-09-18
JP2001514931A5 JP2001514931A5 (enExample) 2006-02-16
JP5227487B2 true JP5227487B2 (ja) 2013-07-03

Family

ID=25433955

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000509454A Expired - Fee Related JP5227487B2 (ja) 1997-08-18 1998-08-14 移植可能なプロテーゼ用の生体溶解吸収性組成物

Country Status (8)

Country Link
US (4) US5854382A (enExample)
EP (1) EP1019096B1 (enExample)
JP (1) JP5227487B2 (enExample)
AT (1) ATE278423T1 (enExample)
AU (1) AU8700898A (enExample)
CA (1) CA2303807C (enExample)
DE (1) DE69826882T2 (enExample)
WO (1) WO1999008718A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008213487A (ja) * 2003-02-28 2008-09-18 Zink Imaging Llc 画像化システム
US8743250B2 (en) 2000-04-12 2014-06-03 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device and method of driving the same

Families Citing this family (222)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7060287B1 (en) 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US7968110B2 (en) * 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US7611533B2 (en) 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
PT876165E (pt) 1995-12-18 2006-10-31 Angiotech Biomaterials Corp Composicoes de polimeros reticulados e processos para a sua utilizacao
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US7883693B2 (en) * 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6441025B2 (en) * 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
SI0932399T1 (sl) 1996-03-12 2006-10-31 Pg Txl Co Lp Vodotopna paklitakselna predzdravila
CN1126537C (zh) * 1996-05-23 2003-11-05 株式会社三养社 可局部给药,可生物降解和持续释放的用于治疗牙周炎的药物组合物及其制备方法
JP2000511095A (ja) * 1996-05-31 2000-08-29 ザ・ユニヴァーシティ・オヴ・ウェスタン・オンタリオ 拡張可能な生体補綴弁ステント
US6696499B1 (en) * 1996-07-11 2004-02-24 Life Medical Sciences, Inc. Methods and compositions for reducing or eliminating post-surgical adhesion formation
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US7009034B2 (en) 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US6566406B1 (en) 1998-12-04 2003-05-20 Incept, Llc Biocompatible crosslinked polymers
US6579224B1 (en) 1999-10-11 2003-06-17 Uromedica, Inc. Apparatus and method for inserting an adjustable implantable genitourinary device
US6045498A (en) * 1997-06-12 2000-04-04 Uromedica, Inc. Method for adjustably restricting a body lumen
US6419624B1 (en) 1999-10-11 2002-07-16 Uromedica, Inc. Apparatus and method for inserting an adjustable implantable genitourinary device
US6645138B2 (en) 1997-09-12 2003-11-11 Uromedica, Inc. Adjustable implantable genitourinary device
US7364540B1 (en) 1997-06-12 2008-04-29 Uromedica, Inc. Implantable device and method for adjustably restricting a body lumen
US6211249B1 (en) * 1997-07-11 2001-04-03 Life Medical Sciences, Inc. Polyester polyether block copolymers
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US5854382A (en) * 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
US6316522B1 (en) 1997-08-18 2001-11-13 Scimed Life Systems, Inc. Bioresorbable hydrogel compositions for implantable prostheses
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US7637948B2 (en) 1997-10-10 2009-12-29 Senorx, Inc. Tissue marking implant
US6638308B2 (en) * 1997-10-10 2003-10-28 John D. Corbitt, Jr. Bioabsorbable breast implant
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
US8288745B2 (en) 1997-10-10 2012-10-16 Senorx, Inc. Method of utilizing an implant for targeting external beam radiation
US6749617B1 (en) 1997-11-04 2004-06-15 Scimed Life Systems, Inc. Catheter and implants for the delivery of therapeutic agents to tissues
CA2327730A1 (en) 1998-04-10 1999-10-21 Wm Marsh Rice University Synthesis of poly(propylene fumarate) by acylation of propylene glycol in the presence of a proton scavenger
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US7347850B2 (en) 1998-08-14 2008-03-25 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
US7790192B2 (en) 1998-08-14 2010-09-07 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
EP1669042A3 (en) * 1998-09-10 2006-06-28 Percardia, Inc. TMR shunt
RU2135122C1 (ru) * 1998-12-17 1999-08-27 Закрытое акционерное общество "ОстМедКонсалт" Способ омолаживания кожи
US6309380B1 (en) * 1999-01-27 2001-10-30 Marian L. Larson Drug delivery via conformal film
US8498693B2 (en) 1999-02-02 2013-07-30 Senorx, Inc. Intracorporeal marker and marker delivery device
US6725083B1 (en) 1999-02-02 2004-04-20 Senorx, Inc. Tissue site markers for in VIVO imaging
US9820824B2 (en) 1999-02-02 2017-11-21 Senorx, Inc. Deployment of polysaccharide markers for treating a site within a patent
US7651505B2 (en) 2002-06-17 2010-01-26 Senorx, Inc. Plugged tip delivery for marker placement
US20090216118A1 (en) 2007-07-26 2009-08-27 Senorx, Inc. Polysaccharide markers
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US7983734B2 (en) 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
US6716445B2 (en) 1999-04-12 2004-04-06 Cornell Research Foundation, Inc. Hydrogel entrapping therapeutic agent and stent with coating comprising this
ES2298135T3 (es) * 1999-04-12 2008-05-16 Cornell Research Foundation, Inc. Sistema formador de hidrogel con componentes hidrofobos e hidrofilos.
JP2002542339A (ja) * 1999-04-16 2002-12-10 ダブリューエム・マーシュ・ライス・ユニバーシティー 機能化されたポリ(プロピレンフマラート)及び(プロピレンフマラート−エチレングリコール)コポリマー
AU4684500A (en) 1999-04-30 2000-11-17 Uromedica, Inc. Method and apparatus for adjustable sling for treatment of urinary stress incontinence
US6926724B1 (en) * 1999-05-04 2005-08-09 City Of Hope Visceral anastomotic device and method of using same
US6579951B1 (en) * 1999-06-08 2003-06-17 Life Medical Sciences, Inc. Chain-extended or crosslinked polyethylene oxide/polypropylene oxide/polyethylene oxide block polymer with optional polyester blocks
US6575991B1 (en) 1999-06-17 2003-06-10 Inrad, Inc. Apparatus for the percutaneous marking of a lesion
US6352667B1 (en) * 1999-08-24 2002-03-05 Absorbable Polymer Technologies, Inc. Method of making biodegradable polymeric implants
US7008635B1 (en) 1999-09-10 2006-03-07 Genzyme Corporation Hydrogels for orthopedic repair
US20030054977A1 (en) * 1999-10-12 2003-03-20 Cell Therapeutics, Inc. Manufacture of polyglutamate-therapeutic agent conjugates
US6521284B1 (en) * 1999-11-03 2003-02-18 Scimed Life Systems, Inc. Process for impregnating a porous material with a cross-linkable composition
US6710126B1 (en) 1999-11-15 2004-03-23 Bio Cure, Inc. Degradable poly(vinyl alcohol) hydrogels
US20050119737A1 (en) * 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
AU3458301A (en) * 2000-01-25 2001-08-07 Edwards Lifesciences Corporation Bioactive coatings to prevent tissue overgrowth on artificial heart valves
CA2402773C (en) * 2000-03-13 2011-10-11 Biocure, Inc. Tissue bulking and coating compositions
WO2001068720A1 (en) 2000-03-13 2001-09-20 Biocure, Inc. Embolic compositions
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8460367B2 (en) 2000-03-15 2013-06-11 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US20020077290A1 (en) * 2000-03-17 2002-06-20 Rama Bhatt Polyglutamic acid-camptothecin conjugates and methods of preparation
US6884778B2 (en) * 2000-04-14 2005-04-26 William Marsh Rice University Biocompatible macromers
US6673385B1 (en) 2000-05-31 2004-01-06 Advanced Cardiovascular Systems, Inc. Methods for polymeric coatings stents
US7682648B1 (en) 2000-05-31 2010-03-23 Advanced Cardiovascular Systems, Inc. Methods for forming polymeric coatings on stents
US6974473B2 (en) 2000-06-30 2005-12-13 Vascular Architects, Inc. Function-enhanced thrombolytic AV fistula and method
MY130475A (en) * 2000-08-25 2007-06-29 Contura As Polyacrylamide hydrogel and its use as an endoprosthesis
US6716444B1 (en) 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US6953560B1 (en) 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
AU2002253785A1 (en) * 2000-11-08 2003-03-03 Boston Scientific Limited Catheter and implants for the delivery of therapeutic agents to tissues
EP2319449B1 (en) 2000-11-20 2016-03-09 Senorx, Inc. Tissue site markers for in vivo imaging
AU3104102A (en) * 2000-12-18 2002-07-01 Univ Texas Local regional chemotherapy and radiotherapy using in situ hydrogel
US6663662B2 (en) 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US20060089721A1 (en) * 2001-01-17 2006-04-27 Muhanna Nabil L Intervertebral disc prosthesis and methods of implantation
WO2002092667A1 (en) * 2001-05-14 2002-11-21 Johns Hopkins Singapore Pte Ltd. Biodegradable polyphosphates for controlled release of bioactive substances
GB0113697D0 (en) * 2001-06-06 2001-07-25 Smith & Nephew Fixation devices for tissue repair
JP2004535431A (ja) 2001-06-22 2004-11-25 サザン バイオシステムズ, インコーポレイテッド ゼロ次長期放出同軸インプラント
WO2003002243A2 (en) 2001-06-27 2003-01-09 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US7022135B2 (en) * 2001-08-17 2006-04-04 Medtronic, Inc. Film with highly porous vascular graft prostheses
US6488952B1 (en) 2001-08-28 2002-12-03 John P. Kennedy Semisolid therapeutic delivery system and combination semisolid, multiparticulate, therapeutic delivery system
US6753071B1 (en) * 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
AU2002350115A1 (en) * 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
US7629388B2 (en) * 2001-11-20 2009-12-08 William Marsh Rice University Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion
US7205337B2 (en) * 2001-12-21 2007-04-17 Isotis Orthobiologics, Inc. End-capped polymers and compositions containing such compounds
AU2002357898A1 (en) * 2001-12-21 2003-07-15 Gensci Orthobiologics, Inc. End-capped polyalkylene glycols and compositions containing such compounds
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
MXPA04011651A (es) * 2002-05-24 2005-03-07 Angiotech Pharm Inc Composiciones y metodo para recubrir implantes medicos.
US20030235610A1 (en) * 2002-06-21 2003-12-25 Piedmont Pharmaceuticals, Llc Liposomes containing biologically active compounds
US7550004B2 (en) * 2002-08-20 2009-06-23 Cook Biotech Incorporated Endoluminal device with extracellular matrix material and methods
CN1684641A (zh) 2002-09-26 2005-10-19 血管内装置有限公司 用于递送丝裂霉素通过洗脱生物相容可移植医疗器件的装置和方法
DE10253391A1 (de) * 2002-11-15 2004-06-03 Mnemoscience Gmbh Amorphe polymere Netzwerke
US20060036158A1 (en) 2003-11-17 2006-02-16 Inrad, Inc. Self-contained, self-piercing, side-expelling marking apparatus
JP2006516548A (ja) * 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
US7877133B2 (en) 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
US7169404B2 (en) * 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US20050096446A1 (en) * 2003-10-29 2005-05-05 Council Of Scientific And Industrial Tri-block copolymers and a process for the preparation of the same
US20050273002A1 (en) 2004-06-04 2005-12-08 Goosen Ryan L Multi-mode imaging marker
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
WO2005051444A2 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Soft tissue implants and anti-scarring agents
US7329531B2 (en) * 2003-12-12 2008-02-12 Scimed Life Systems, Inc. Blood-tight implantable textile material and method of making
US20050214339A1 (en) * 2004-03-29 2005-09-29 Yiwen Tang Biologically degradable compositions for medical applications
US9498563B2 (en) * 2004-04-23 2016-11-22 Boston Scientific Scimed, Inc. Medical articles having therapeutic-agent-containing regions formed from coalesced polymer particles
KR100974733B1 (ko) 2004-04-28 2010-08-06 안지오디바이스 인터내셔널 게엠베하 가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
US20050255230A1 (en) * 2004-05-17 2005-11-17 Clerc Claude O Method of manufacturing a covered stent
US7803182B2 (en) * 2004-05-28 2010-09-28 Cordis Corporation Biodegradable vascular device with buffering agent
WO2005120462A2 (en) * 2004-06-07 2005-12-22 Callisyn Pharmaceuticals, Inc. Biodegradable and biocompatible crosslinked polymer hydrogel prepared from pva and/or peg macromer mixtures
WO2005123903A2 (en) * 2004-06-10 2005-12-29 Johns Hopkins University Culture aid for cells and tissues
CA2570960C (en) 2004-06-17 2013-10-01 Valera Pharmaceuticals, Inc. Compositions and methods for treating central precocious puberty
DE102004030347B4 (de) * 2004-06-18 2006-08-03 Aesculap Ag & Co. Kg Implantat
JP4857268B2 (ja) * 2004-06-29 2012-01-18 バイオキュア・インコーポレーテッド 脊椎椎間板髄核移植片
US8119153B2 (en) * 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
CA2581093C (en) 2004-09-17 2014-11-18 Angiotech Biomaterials Corporation Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
WO2006036681A2 (en) * 2004-09-22 2006-04-06 Cartilix, Inc. Cartilage filling device
US20090011116A1 (en) * 2004-09-28 2009-01-08 Atrium Medical Corporation Reducing template with coating receptacle containing a medical device to be coated
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9801982B2 (en) * 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
US8367099B2 (en) * 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
US8312836B2 (en) * 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US20060088596A1 (en) 2004-09-28 2006-04-27 Atrium Medical Corporation Solubilizing a drug for use in a coating
EP1812022B1 (en) 2004-09-28 2014-01-15 Atrium Medical Corporation Stand-alone film and methods for making the same
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US20060073208A1 (en) 2004-10-01 2006-04-06 Allergan, Inc. Cosmetic neurotoxin compositions and methods
ES2748926T3 (es) 2004-10-18 2020-03-18 Covidien Lp Fijaciones quirúrgicas recubiertas con materiales de tratamiento de heridas
CA2583826A1 (en) * 2004-10-22 2006-05-04 Benitec, Inc. Therapeutic rnai agents for treating psoriasis
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
US10362947B2 (en) 2005-03-15 2019-07-30 Integra LifeSciences Switzerland Sarl Pressure sensing devices
AU2006200951B2 (en) * 2005-03-13 2012-01-19 Integra LifeSciences Switzerland Sarl Pressure sensing devices
US20060222596A1 (en) 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US10357328B2 (en) 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
US20060257355A1 (en) * 2005-05-10 2006-11-16 Abiomed, Inc. Impregnated polymer compositions and devices using them
CN1330299C (zh) * 2005-05-13 2007-08-08 山东蓝金生物工程有限公司 一种治疗颅外实体肿瘤的药物组合物
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) * 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US8052658B2 (en) 2005-10-07 2011-11-08 Bard Peripheral Vascular, Inc. Drug-eluting tissue marker
AU2006304590A1 (en) 2005-10-15 2007-04-26 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US20070112300A1 (en) * 2005-11-14 2007-05-17 Roman Ricardo D Balloon folding design, apparatus and method of making the same
US20070149641A1 (en) * 2005-12-28 2007-06-28 Goupil Dennis W Injectable bone cement
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US8236054B2 (en) * 2006-02-08 2012-08-07 Neosthetic, Llc Breast implants and methods of manufacture
US7625405B2 (en) * 2006-02-08 2009-12-01 Neosthetic, Llc Breast implant and method of manufacture
KR20090020544A (ko) * 2006-02-21 2009-02-26 더 트러스티즈 오브 프린스턴 유니버시티 분자의 공유 부착을 위한 중합체 표면의 고수율 활성화
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US7872068B2 (en) 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
EP2054537A2 (en) 2006-08-02 2009-05-06 Boston Scientific Scimed, Inc. Endoprosthesis with three-dimensional disintegration control
US20080294039A1 (en) * 2006-08-04 2008-11-27 Senorx, Inc. Assembly with hemostatic and radiographically detectable pellets
DE102006039346A1 (de) * 2006-08-22 2008-03-13 Biotronik Vi Patent Ag Biokorrodierbares metallisches Implantat mit einer Beschichtung oder Kavitätenfüllung aus einem PEG/PLGA-Copolymer
EP2399616A1 (en) * 2006-09-15 2011-12-28 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis with biostable inorganic layers
US8057534B2 (en) 2006-09-15 2011-11-15 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
US8808726B2 (en) 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
US8002821B2 (en) 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
US8064987B2 (en) 2006-10-23 2011-11-22 C. R. Bard, Inc. Breast marker
WO2008057344A2 (en) * 2006-11-06 2008-05-15 Atrium Medical Corporation Coated surgical mesh
US9492596B2 (en) * 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
EP3542748B1 (en) 2006-12-12 2023-08-16 C. R. Bard, Inc. Multiple imaging mode tissue marker
ES2432572T3 (es) 2006-12-18 2013-12-04 C.R. Bard, Inc. Marcador de biopsia con propiedades de obtención de imágenes generadas in situ
ES2356274T3 (es) 2006-12-28 2011-04-06 Boston Scientific Limited Endoprótesis biodegradables y procedimientos de fabricación de las mismas.
WO2008086794A2 (de) 2007-01-21 2008-07-24 Hemoteq Ag Medizinprodukt zur behandlung von verschlüssen von körperdurchgängen und zur prävention drohender wiederverschlüsse
DE102007024256A1 (de) 2007-05-16 2008-11-20 Gelita Ag Gefäßstent
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US9650479B2 (en) 2007-10-04 2017-05-16 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same
US9040646B2 (en) * 2007-10-04 2015-05-26 W. L. Gore & Associates, Inc. Expandable TFE copolymers, methods of making, and porous, expanded articles thereof
US8637144B2 (en) * 2007-10-04 2014-01-28 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, and porous, expended articles thereof
US8414924B2 (en) * 2007-10-10 2013-04-09 Kyoto University Preparation for treating heart disease used in cell therapy
DE102008006455A1 (de) * 2008-01-29 2009-07-30 Biotronik Vi Patent Ag Implantat mit einem Grundkörper aus einer biokorrodierbaren Legierung und einer korrosionshemmenden Beschichtung
US8311610B2 (en) 2008-01-31 2012-11-13 C. R. Bard, Inc. Biopsy tissue marker
EP2310423A1 (en) * 2008-04-28 2011-04-20 SurModics, Inc. Poly- (1 4)glucopyranose-based matrices with hydrazide crosslinking
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US9327061B2 (en) 2008-09-23 2016-05-03 Senorx, Inc. Porous bioabsorbable implant
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
JP5453453B2 (ja) 2008-12-30 2014-03-26 シー・アール・バード・インコーポレーテッド 組織マーカの配置のためのマーカ伝送装置
EP2403546A2 (en) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Self-buffering medical implants
JP5936536B2 (ja) 2009-03-16 2016-06-22 ユニバーシティー オブ メンフィス リサーチ ファウンデーション 傷に剤を届けるための組成物および方法
JP5684239B2 (ja) 2009-05-04 2015-03-11 インセプト・リミテッド・ライアビリティ・カンパニーIncept Llc 軌道および穿刺部閉鎖用の生体材料
US9309347B2 (en) 2009-05-20 2016-04-12 Biomedical, Inc. Bioresorbable thermoset polyester/urethane elastomers
US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
US20110319987A1 (en) 2009-05-20 2011-12-29 Arsenal Medical Medical implant
US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
EP3858299B1 (en) 2009-05-20 2025-10-08 Lyra Therapeutics, Inc. Method of loading a self-expanding implant
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
ES2550634T3 (es) 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Uso de nanocristales para un balón de suministro de fármaco
US10080821B2 (en) 2009-07-17 2018-09-25 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
US8372133B2 (en) 2009-10-05 2013-02-12 480 Biomedical, Inc. Polymeric implant delivery system
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US9045657B2 (en) 2010-03-24 2015-06-02 The Board Of Trustees Of The University Of Illinois Viscoelastic ink for direct writing of hydrogel structures
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
US10322213B2 (en) 2010-07-16 2019-06-18 Atrium Medical Corporation Compositions and methods for altering the rate of hydrolysis of cured oil-based materials
WO2012031236A1 (en) 2010-09-02 2012-03-08 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
ES2601211T3 (es) 2011-03-09 2017-02-14 Occlugel Polímero biorreabsorbible implantable cargado con macromoléculas frágiles
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
EP2744480B8 (en) 2011-08-17 2019-06-26 Keratin Biosciences, Inc. Low protein percentage gelling compositions
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
CN103998069A (zh) * 2011-10-17 2014-08-20 聚合-医药有限公司 可吸收的原位凝胶形成系统、其制备方法及用途
WO2013123507A1 (en) * 2012-02-17 2013-08-22 Bacterin International, Inc. Composition of and method for forming reduced viscosity polymeric coatings
US8808372B2 (en) * 2012-04-27 2014-08-19 Cold Winter Solutions, L.L.C. Breast implant spacers for the treatment of periprosthetic breast implant infections
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
USD715942S1 (en) 2013-09-24 2014-10-21 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715442S1 (en) 2013-09-24 2014-10-14 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716451S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716450S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
KR102421923B1 (ko) 2014-07-17 2022-07-18 더 리전트 오브 더 유니버시티 오브 캘리포니아 생물의학적 적용을 위한 제어가능한 자기-어닐링 마이크로겔 입자
US9644054B2 (en) 2014-12-19 2017-05-09 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same
WO2017142879A1 (en) 2016-02-16 2017-08-24 The Regents Of The University Of California Methods for immune system modulation with microporous annealed particle gels
EP3562523A4 (en) 2016-12-29 2020-09-30 Tempo Therapeutics, Inc. PROCESSES AND SYSTEMS FOR THE TREATMENT OF A MEDICAL IMPLANT SITE
CA3099139A1 (en) 2018-05-03 2019-11-07 Collplant Ltd. Dermal fillers and applications thereof
US11510766B2 (en) 2019-02-14 2022-11-29 Uromedica, Inc. Method and apparatus for monitoring implantable device for urinary continence
CN111467500B (zh) * 2020-03-23 2022-08-09 北京工业大学 一种低氧双靶向性agt抑制剂偶联物及其制备方法与应用
CN113577246B (zh) * 2021-08-02 2023-11-03 赛克赛斯生物科技股份有限公司 一种预防瘢痕粘连的组合物、术后防粘连材料及应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6037735B2 (ja) * 1978-10-18 1985-08-28 住友電気工業株式会社 人工血管
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US5034265A (en) * 1983-08-01 1991-07-23 Washington Research Foundation Plasma gas discharge treatment for improving the compatibility of biomaterials
US4842575A (en) * 1984-01-30 1989-06-27 Meadox Medicals, Inc. Method for forming impregnated synthetic vascular grafts
CA1292597C (en) * 1985-12-24 1991-12-03 Koichi Okita Tubular prothesis having a composite structure
JPH0696023B2 (ja) * 1986-11-10 1994-11-30 宇部日東化成株式会社 人工血管およびその製造方法
IL82834A (en) * 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
KR920000459B1 (ko) * 1989-12-13 1992-01-14 재단법인 한국화학연구소 다당류 유도체가 도포된 인공혈관과 그 제조방법
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5462990A (en) * 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
NZ240451A (en) * 1990-11-15 1993-03-26 Iolab Corp Mixture of a water-soluble polymer and a chitosan having 30-60% n-acetylation; corneal bandage lenses
IT1244808B (it) * 1990-11-29 1994-09-05 Giovanni Brotzu Protesi vascolare sintetica biocompatibile a doppia parete contenente cellule ormonosecernenti
US5584875A (en) * 1991-12-20 1996-12-17 C. R. Bard, Inc. Method for making vascular grafts
US5573934A (en) * 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
US5202413A (en) * 1993-02-16 1993-04-13 E. I. Du Pont De Nemours And Company Alternating (ABA)N polylactide block copolymers
AU4997493A (en) * 1993-06-29 1995-01-24 W.L. Gore & Associates, Inc. Improved cardiovascular patch materials and method for producing same
US5962023A (en) * 1995-03-06 1999-10-05 Ethicon, Inc. Hydrogels containing absorbable polyoxaamides
US5618850A (en) * 1995-03-09 1997-04-08 Focal, Inc. Hydroxy-acid cosmetics
US6201065B1 (en) * 1995-07-28 2001-03-13 Focal, Inc. Multiblock biodegradable hydrogels for drug delivery and tissue treatment
US5854382A (en) * 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8743250B2 (en) 2000-04-12 2014-06-03 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device and method of driving the same
JP2008213487A (ja) * 2003-02-28 2008-09-18 Zink Imaging Llc 画像化システム

Also Published As

Publication number Publication date
US5854382A (en) 1998-12-29
WO1999008718A2 (en) 1999-02-25
AU8700898A (en) 1999-03-08
US6028164A (en) 2000-02-22
US6005020A (en) 1999-12-21
US6403758B1 (en) 2002-06-11
DE69826882D1 (de) 2004-11-11
DE69826882T2 (de) 2005-11-10
EP1019096A2 (en) 2000-07-19
ATE278423T1 (de) 2004-10-15
CA2303807C (en) 2008-01-22
JP2001514931A (ja) 2001-09-18
EP1019096B1 (en) 2004-10-06
CA2303807A1 (en) 1999-02-25
WO1999008718A3 (en) 1999-05-20

Similar Documents

Publication Publication Date Title
JP5227487B2 (ja) 移植可能なプロテーゼ用の生体溶解吸収性組成物
US6534560B2 (en) Bioresorbable hydrogel compositions for implantable prostheses
Piskin Biodegradable polymers as biomaterials
US8574311B2 (en) Versatile biodegradable elastic polymers featured with dual crosslinking mechanism for biomedical applications
US7901705B2 (en) Antimicrobial releasing polymers
EP2629762B1 (en) Pendant hydrophile bearing biodegradable compositions and related devices
Miri et al. Updates on polyurethane and its multifunctional applications in biomedical engineering
CA2798459A1 (en) Glycerol ester active agent delivery systems and methods
KR100464930B1 (ko) 조직재생 유도용 차폐막 및 그의 제조방법
EP3435988B1 (en) Drug-containing particulate composition with cationic agent, associated medical devices, and methods for treatment
Chu Biodegradable polymers: an overview
San Román et al. Contribution of polymeric supports to the development of tissue engineering
Himmelstein et al. Current Literature Reviews: Bioactive and Compatible Citation Index
Leamy Christopher Batich

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050815

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050815

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090615

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090915

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090925

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091215

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100121

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100520

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100726

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20100729

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20110107

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110812

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110817

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121219

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130318

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20160322

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees