JP5149001B2 - 癌の処置におけるマイグラスタチンアナログ - Google Patents

癌の処置におけるマイグラスタチンアナログ Download PDF

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Publication number
JP5149001B2
JP5149001B2 JP2007515355A JP2007515355A JP5149001B2 JP 5149001 B2 JP5149001 B2 JP 5149001B2 JP 2007515355 A JP2007515355 A JP 2007515355A JP 2007515355 A JP2007515355 A JP 2007515355A JP 5149001 B2 JP5149001 B2 JP 5149001B2
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Japan
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hydrogen
composition
aryl
compound
compounds
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JP2007515355A
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English (en)
Japanese (ja)
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JP2008500366A (ja
JP2008500366A5 (OSRAM
Inventor
サミュエル ジェイ. ダニシェフスキー,
クリストフ ガウル,
ジョン ティー. ヌジャーダーソン,
マルコム エー. エス. ムーア,
カイダ ウー,
デイビッド シー. ドーン,
ミヒルバラン マンダル,
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Memorial Sloan Kettering Cancer Center
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Memorial Sloan Kettering Cancer Center
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Publication of JP2008500366A publication Critical patent/JP2008500366A/ja
Publication of JP2008500366A5 publication Critical patent/JP2008500366A5/ja
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Publication of JP5149001B2 publication Critical patent/JP5149001B2/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2007515355A 2004-05-25 2005-05-25 癌の処置におけるマイグラスタチンアナログ Expired - Fee Related JP5149001B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57411404P 2004-05-25 2004-05-25
US60/574,114 2004-05-25
PCT/US2005/018603 WO2006001967A2 (en) 2004-05-25 2005-05-25 Migrastatin analogs in the treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008136097A Division JP2008273981A (ja) 2004-05-25 2008-05-23 癌の処置におけるマイグラスタチンアナログ

Publications (3)

Publication Number Publication Date
JP2008500366A JP2008500366A (ja) 2008-01-10
JP2008500366A5 JP2008500366A5 (OSRAM) 2008-07-10
JP5149001B2 true JP5149001B2 (ja) 2013-02-20

Family

ID=35355865

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007515355A Expired - Fee Related JP5149001B2 (ja) 2004-05-25 2005-05-25 癌の処置におけるマイグラスタチンアナログ
JP2008136097A Pending JP2008273981A (ja) 2004-05-25 2008-05-23 癌の処置におけるマイグラスタチンアナログ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008136097A Pending JP2008273981A (ja) 2004-05-25 2008-05-23 癌の処置におけるマイグラスタチンアナログ

Country Status (3)

Country Link
US (1) US8957056B2 (OSRAM)
JP (2) JP5149001B2 (OSRAM)
WO (1) WO2006001967A2 (OSRAM)

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JP5149001B2 (ja) 2004-05-25 2013-02-20 スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ 癌の処置におけるマイグラスタチンアナログ
US8188141B2 (en) * 2004-09-23 2012-05-29 Sloan-Kettering Institute For Cancer Research Isomigrastatin analogs in the treatment of cancer
SI2109623T1 (sl) * 2006-05-22 2012-05-31 Xbiotech Inc Zdravljenje raka z anti il protitelesi
US20080312317A1 (en) * 2007-04-12 2008-12-18 Eisai R&D Management Co., Ltd. 12 membered-ring macrolactam derivatives
CA2707009A1 (en) * 2007-11-21 2009-06-04 Cornell University Methods for inhibiting fascin
PL2285409T3 (pl) 2008-05-30 2016-10-31 Przeciwciała il-1 alfa
EP2379074B1 (en) * 2008-12-17 2013-11-13 Sanofi Macrolactone derivatives, method for the production thereof and use thereof for the treatment of cancer
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
ES2703774T3 (es) 2010-06-18 2019-03-12 Xbiotech Inc Tratamiento para la artritis
NZ607472A (en) 2010-08-23 2014-09-26 Xbiotech Inc Treatment for neoplastic diseases
US9724409B2 (en) 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
KR102004554B1 (ko) 2011-04-01 2019-10-01 엑스바이오테크, 인크. 피부과학적 병리의 치료
CN103635088B (zh) * 2011-04-07 2016-06-15 索隆-基特林癌症研究协会 米格拉他汀类(Migrastatins)和其用途
WO2013013240A2 (en) * 2011-07-21 2013-01-24 Theracrine, Inc. Macrocyclic compounds and related compositons and methods of use
MX356808B (es) 2011-09-23 2018-06-14 Xbiotech Inc Uso de una composición farmacéutica que comprende un anticuerpo anti-il-1a para el tratamiento de la caquexia.
US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
JP6783224B2 (ja) 2014-04-04 2020-11-11 デル マー ファーマシューティカルズ 肺の非小細胞癌腫及び卵巣癌を処置するためのジアンヒドロガラクチトール及びその類縁体又は誘導体の使用
EP3582813A4 (en) 2017-02-16 2020-12-30 XBiotech, Inc TREATMENT OF SUPPURATIVE HIDRADENITIS
CA3095740A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin alpha (il-1a)
CA3095679A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleuken 1 alpha (il-1a)
CA3095675A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)
CA3095676A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)

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US8188141B2 (en) 2004-09-23 2012-05-29 Sloan-Kettering Institute For Cancer Research Isomigrastatin analogs in the treatment of cancer
CA2707009A1 (en) 2007-11-21 2009-06-04 Cornell University Methods for inhibiting fascin

Also Published As

Publication number Publication date
JP2008500366A (ja) 2008-01-10
WO2006001967A2 (en) 2006-01-05
WO2006001967A3 (en) 2006-07-27
JP2008273981A (ja) 2008-11-13
US20090124662A1 (en) 2009-05-14
US8957056B2 (en) 2015-02-17

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