JP5091106B2 - 真性糖尿病の治療のためのロフルミラスト - Google Patents
真性糖尿病の治療のためのロフルミラスト Download PDFInfo
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- JP5091106B2 JP5091106B2 JP2008500172A JP2008500172A JP5091106B2 JP 5091106 B2 JP5091106 B2 JP 5091106B2 JP 2008500172 A JP2008500172 A JP 2008500172A JP 2008500172 A JP2008500172 A JP 2008500172A JP 5091106 B2 JP5091106 B2 JP 5091106B2
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- diabetes
- pharmaceutically acceptable
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- acceptable salt
- treatment
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
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| EP05101772 | 2005-03-08 | ||
| EP05101772.1 | 2005-03-08 | ||
| PCT/EP2006/060418 WO2006094933A1 (en) | 2005-03-08 | 2006-03-03 | Roflumilast for the treatment of diabetes mellitus |
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| JP2012129982A Division JP5611275B2 (ja) | 2005-03-08 | 2012-06-07 | 真性糖尿病の治療のためのロフルミラスト |
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| JP2012129982A Expired - Fee Related JP5611275B2 (ja) | 2005-03-08 | 2012-06-07 | 真性糖尿病の治療のためのロフルミラスト |
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| BR0307589A (pt) | 2002-02-11 | 2005-02-01 | Antares Pharma Inc | Dispositivo de injeção intradérmica |
| JP5216328B2 (ja) | 2005-01-24 | 2013-06-19 | アンタレス ファーマ インコーポレイテッド | あらかじめ充填された針補助シリンジジェット式注射器 |
| MX2007010560A (es) * | 2005-03-08 | 2008-02-21 | Nycomed Gmbh | Roflumilast para el tratamiento de diabetes mellitus. |
| TW200738266A (en) * | 2005-09-29 | 2007-10-16 | Sankyo Co | Pharmaceutical agent containing insulin resistance improving agent |
| US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
| UA100497C2 (ru) * | 2006-09-07 | 2013-01-10 | Никомед Гмбх | Комбинированное лечение сахарного диабета |
| EP2990067B1 (en) | 2008-03-10 | 2019-09-04 | Antares Pharma, Inc. | Injector safety device |
| CN101548972B (zh) * | 2008-04-03 | 2012-10-17 | 万特制药(海南)有限公司 | 一种含有瑞格列奈的固体药物组合物 |
| JP5611208B2 (ja) | 2008-08-05 | 2014-10-22 | アンタレス・ファーマ・インコーポレーテッド | 多数回服用量の注射装置 |
| JP5732039B2 (ja) | 2009-03-20 | 2015-06-10 | アンタレス・ファーマ・インコーポレーテッド | 危険有害性薬剤の注入システム |
| US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
| US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US20130172303A1 (en) * | 2012-01-03 | 2013-07-04 | Forest Laboratories Holdings Ltd. | Roflumilast compositions for the treatment of copd |
| JP6165786B2 (ja) | 2012-03-06 | 2017-07-19 | アンタレス・ファーマ・インコーポレーテッド | 離脱力特徴を備える充填シリンジ |
| AU2013203784A1 (en) | 2012-04-06 | 2013-10-24 | Kaushik J. Dave | Needle assisted jet injection administration of testosterone compositions |
| US9364611B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
| EP2953667B1 (en) | 2013-02-11 | 2019-10-23 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
| WO2014124860A1 (en) | 2013-02-14 | 2014-08-21 | Boehringer Ingelheim International Gmbh | Specific pde4b-inhibitors for the treatment of diabetes mellitus |
| WO2014164786A1 (en) * | 2013-03-11 | 2014-10-09 | Madsen Patrick | Dosage injector with pinion system |
| WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
| EP3165224A1 (en) * | 2015-11-09 | 2017-05-10 | Albert-Ludwigs-Universität Freiburg | Use of pde4 inhibitors for the prophylaxis and/or therapy of dyslipoproteinaemia and related disorders |
| US11267861B2 (en) | 2016-04-19 | 2022-03-08 | Ureka Sarl | Peptide-oligourea foldamer compounds and methods of their use |
| GB202306663D0 (en) * | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Combination therapy |
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| WO2004098597A1 (en) | 2003-05-12 | 2004-11-18 | Altana Pharma Ag | Composition comprising roflumilast and shuil-1r ii |
| WO2004098596A1 (en) | 2003-05-12 | 2004-11-18 | Altana Pharma Ag | Composition comprising roflumilast and il-1 trap |
| WO2004098598A1 (en) | 2003-05-12 | 2004-11-18 | Altana Pharma Ag | COMPOSITION COMPRISING ROFLUMILAST AND A TNFα ANTAGONIST |
| WO2004098595A1 (en) | 2003-05-12 | 2004-11-18 | Altana Pharma Ag | COMPOSITION COMPRISING ROFLUMILAST AND A TNFα ANTAGONIST |
| CA2525946C (en) * | 2003-05-22 | 2013-01-29 | Altana Pharma Ag | Composition comprising a pde4 inhibitor and a pde5 inhibitor |
| WO2005020926A2 (en) * | 2003-08-28 | 2005-03-10 | Pharmacia Corporation | Treatment or prevention of vascular disorders with cox-2 inhibitors in combination with cyclic amp-specific phosphodiesterase inhibitors |
| WO2005023253A1 (en) * | 2003-09-05 | 2005-03-17 | Altana Pharma Ag | Use of pde4 inhibitors for the treatment of diabetes mellitus |
| CA2542277A1 (en) | 2003-10-21 | 2005-05-12 | Pharmacia Corporation | Method for the treatment or prevention of respiratory inflammation with a cyclooxygenase-2 inhibitor in combination with a phosphodiesterase 4 inhibitor and compositions therewith |
| TW200539867A (en) | 2004-04-13 | 2005-12-16 | Arena Pharm Inc | Human g protein-coupled receptor and modulators thereof for the treatment of hyperglycemia and related disorders |
| MX2007010560A (es) * | 2005-03-08 | 2008-02-21 | Nycomed Gmbh | Roflumilast para el tratamiento de diabetes mellitus. |
-
2006
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- 2006-03-03 BR BRPI0609371-0A patent/BRPI0609371A2/pt not_active IP Right Cessation
- 2006-03-03 AU AU2006222060A patent/AU2006222060B2/en not_active Ceased
- 2006-03-03 JP JP2008500172A patent/JP5091106B2/ja not_active Expired - Fee Related
- 2006-03-03 CN CN2012100579547A patent/CN102600144A/zh active Pending
- 2006-03-03 WO PCT/EP2006/060418 patent/WO2006094933A1/en not_active Ceased
- 2006-03-03 KR KR1020077022434A patent/KR101302838B1/ko not_active Expired - Fee Related
- 2006-03-03 US US11/885,450 patent/US8017633B2/en not_active Expired - Fee Related
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- 2006-03-03 EP EP06708617A patent/EP1874308A1/en not_active Withdrawn
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- 2006-03-03 NZ NZ560269A patent/NZ560269A/en not_active IP Right Cessation
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2007
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- 2007-08-14 IL IL185277A patent/IL185277A/en not_active IP Right Cessation
- 2007-10-01 NO NO20074943A patent/NO20074943L/no not_active Application Discontinuation
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Also Published As
| Publication number | Publication date |
|---|---|
| JP5611275B2 (ja) | 2014-10-22 |
| AU2006222060A1 (en) | 2006-09-14 |
| EA200701845A1 (ru) | 2008-02-28 |
| US20080214625A1 (en) | 2008-09-04 |
| NZ560269A (en) | 2010-12-24 |
| US20110269750A1 (en) | 2011-11-03 |
| HK1116077A1 (en) | 2008-12-19 |
| NO20074943L (no) | 2007-10-01 |
| CA2599376A1 (en) | 2006-09-14 |
| KR20070111539A (ko) | 2007-11-21 |
| CN102600144A (zh) | 2012-07-25 |
| CN101137368A (zh) | 2008-03-05 |
| IL221006A0 (en) | 2012-08-30 |
| IL185277A0 (en) | 2008-02-09 |
| US8017633B2 (en) | 2011-09-13 |
| EA015382B1 (ru) | 2011-08-30 |
| JP2012188448A (ja) | 2012-10-04 |
| EP1874308A1 (en) | 2008-01-09 |
| AU2006222060B2 (en) | 2011-09-01 |
| US8541456B2 (en) | 2013-09-24 |
| BRPI0609371A2 (pt) | 2010-03-30 |
| CA2599376C (en) | 2014-05-13 |
| JP2008532974A (ja) | 2008-08-21 |
| IL185277A (en) | 2013-08-29 |
| KR101302838B1 (ko) | 2013-09-03 |
| MX2007010560A (es) | 2008-02-21 |
| CN101137368B (zh) | 2012-05-16 |
| ZA200706294B (en) | 2008-09-25 |
| WO2006094933A1 (en) | 2006-09-14 |
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