JP5036727B2 - ヘパリン結合タンパク質の組み換え体産生 - Google Patents

ヘパリン結合タンパク質の組み換え体産生 Download PDF

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Publication number
JP5036727B2
JP5036727B2 JP2008547733A JP2008547733A JP5036727B2 JP 5036727 B2 JP5036727 B2 JP 5036727B2 JP 2008547733 A JP2008547733 A JP 2008547733A JP 2008547733 A JP2008547733 A JP 2008547733A JP 5036727 B2 JP5036727 B2 JP 5036727B2
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vegf
support
heparin
refolding
buffer solution
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Japanese (ja)
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JP2009521232A5 (https=
JP2009521232A (ja
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ミシェル ディー． バトラー，
ジェフリー エル． クレランド，
デービッド ダブリュー． カーン，
シェリー ピザーロ，
チャールズ エイチ． シュメルツァー，
マージョリー イー． ウィンクラー，
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ジェネンテック， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2008547733A 2005-12-22 2006-12-19 ヘパリン結合タンパク質の組み換え体産生 Active JP5036727B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US75361505P 2005-12-22 2005-12-22
US60/753,615 2005-12-22
US80743206P 2006-07-14 2006-07-14
US60/807,432 2006-07-14
PCT/US2006/062320 WO2007130154A2 (en) 2005-12-22 2006-12-19 Recombinant production of heparin binding proteins

Related Child Applications (1)

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JP2011174491A Division JP2011254831A (ja) 2005-12-22 2011-08-10 ヘパリン結合タンパク質の組み換え体産生

Publications (3)

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JP2009521232A JP2009521232A (ja) 2009-06-04
JP2009521232A5 JP2009521232A5 (https=) 2011-09-29
JP5036727B2 true JP5036727B2 (ja) 2012-09-26

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JP2008547733A Active JP5036727B2 (ja) 2005-12-22 2006-12-19 ヘパリン結合タンパク質の組み換え体産生
JP2011174491A Pending JP2011254831A (ja) 2005-12-22 2011-08-10 ヘパリン結合タンパク質の組み換え体産生

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JP2011174491A Pending JP2011254831A (ja) 2005-12-22 2011-08-10 ヘパリン結合タンパク質の組み換え体産生

Country Status (16)

Country Link
US (3) US20080032343A1 (https=)
EP (2) EP2336164A1 (https=)
JP (2) JP5036727B2 (https=)
KR (1) KR101067525B1 (https=)
AR (1) AR058625A1 (https=)
AT (1) ATE497973T1 (https=)
AU (1) AU2006343279B2 (https=)
BR (1) BRPI0621124A2 (https=)
CA (1) CA2633554C (https=)
DE (1) DE602007012412D1 (https=)
IL (1) IL191968A (https=)
MY (1) MY143274A (https=)
NZ (1) NZ568809A (https=)
RU (1) RU2385877C1 (https=)
TW (1) TWI369362B (https=)
WO (1) WO2007130154A2 (https=)

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NZ568809A (en) 2005-12-22 2011-08-26 Genentech Inc Recovering and purification of VEGF proteins from prokaryotic cells using polyanionic agents
US20080125580A1 (en) 2006-07-14 2008-05-29 Genentech, Inc. Refolding of Recombinant Proteins
CA2742817A1 (en) 2008-11-20 2010-05-27 Biogen Idec Ma Inc. Arginine inactivation of viruses
EA020621B1 (ru) 2009-06-22 2014-12-30 Амген Инк. Рефолдинг белков с использованием химически контролируемого окислительно-восстановительного состояния
LT3660032T (lt) 2009-06-25 2026-02-25 Amgen Inc. Ne žinduolių sistemoje ekspresuotų baltymų surišamojo gryninimo būdai
TWI662176B (zh) 2010-02-25 2019-06-11 約翰 克蘭曼特 普瑞斯頓 鷹架
KR102283127B1 (ko) * 2018-06-19 2021-07-29 주식회사 엠디헬스케어 류코노스톡속 균주를 포함하는 간 기능 개선용 조성물
US11180540B2 (en) * 2019-12-06 2021-11-23 Regeneron Pharmaceuticals, Inc. Anti-VEGF protein compositions and methods for producing the same
CN117069810A (zh) * 2022-05-09 2023-11-17 上海科技大学 一种膜蛋白的纯化方法

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Also Published As

Publication number Publication date
IL191968A0 (en) 2008-12-29
DE602007012412D1 (de) 2011-03-24
AR058625A1 (es) 2008-02-13
US20100261888A1 (en) 2010-10-14
NZ568809A (en) 2011-08-26
US20130217867A1 (en) 2013-08-22
KR20080087128A (ko) 2008-09-30
EP2336164A1 (en) 2011-06-22
BRPI0621124A2 (pt) 2011-11-29
WO2007130154A3 (en) 2008-06-26
AU2006343279B2 (en) 2012-03-29
IL191968A (en) 2013-06-27
CA2633554A1 (en) 2007-11-15
EP1973942B1 (en) 2011-02-09
HK1119188A1 (en) 2009-07-17
US20080032343A1 (en) 2008-02-07
TW200734351A (en) 2007-09-16
RU2008130072A (ru) 2010-01-27
WO2007130154A8 (en) 2008-04-17
AU2006343279A1 (en) 2007-11-15
JP2011254831A (ja) 2011-12-22
RU2385877C1 (ru) 2010-04-10
TWI369362B (en) 2012-08-01
MY143274A (en) 2011-04-15
ATE497973T1 (de) 2011-02-15
KR101067525B1 (ko) 2011-09-27
CA2633554C (en) 2012-11-13
JP2009521232A (ja) 2009-06-04
US8906648B2 (en) 2014-12-09
WO2007130154A2 (en) 2007-11-15
EP1973942A2 (en) 2008-10-01

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