DE602007012412D1 - Rekombinante produktion heparinbindender proteine - Google Patents
Rekombinante produktion heparinbindender proteineInfo
- Publication number
- DE602007012412D1 DE602007012412D1 DE602007012412T DE602007012412T DE602007012412D1 DE 602007012412 D1 DE602007012412 D1 DE 602007012412D1 DE 602007012412 T DE602007012412 T DE 602007012412T DE 602007012412 T DE602007012412 T DE 602007012412T DE 602007012412 D1 DE602007012412 D1 DE 602007012412D1
- Authority
- DE
- Germany
- Prior art keywords
- binding proteins
- recombinant production
- heparin binding
- heparin
- recombinant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75361505P | 2005-12-22 | 2005-12-22 | |
US80743206P | 2006-07-14 | 2006-07-14 | |
PCT/US2006/062320 WO2007130154A2 (en) | 2005-12-22 | 2006-12-19 | Recombinant production of heparin binding proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007012412D1 true DE602007012412D1 (de) | 2011-03-24 |
Family
ID=38668202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007012412T Active DE602007012412D1 (de) | 2005-12-22 | 2006-12-19 | Rekombinante produktion heparinbindender proteine |
Country Status (17)
Country | Link |
---|---|
US (3) | US20080032343A1 (de) |
EP (2) | EP1973942B1 (de) |
JP (2) | JP5036727B2 (de) |
KR (1) | KR101067525B1 (de) |
AR (1) | AR058625A1 (de) |
AT (1) | ATE497973T1 (de) |
AU (1) | AU2006343279B2 (de) |
BR (1) | BRPI0621124A2 (de) |
CA (1) | CA2633554C (de) |
DE (1) | DE602007012412D1 (de) |
HK (1) | HK1119188A1 (de) |
IL (1) | IL191968A (de) |
MY (1) | MY143274A (de) |
NZ (1) | NZ568809A (de) |
RU (1) | RU2385877C1 (de) |
TW (1) | TWI369362B (de) |
WO (1) | WO2007130154A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1973942B1 (de) | 2005-12-22 | 2011-02-09 | Genentech, Inc. | Rekombinante produktion heparinbindender proteine |
NZ573639A (en) | 2006-07-14 | 2012-03-30 | Genentech Inc | Refolding of recombinant proteins |
US8980610B2 (en) | 2008-11-20 | 2015-03-17 | Biogen Idec Ma Inc. | Arginine inactivation of viruses |
EP3366692A1 (de) | 2009-06-22 | 2018-08-29 | Amgen, Inc | Proteinneufaltung mit einem chemisch gesteuerten redoxzustand |
MX2011013417A (es) | 2009-06-25 | 2012-03-29 | Amgen Inc | Procesos de purificacion por captura para proteinas expresadas en un sistema no mamifero. |
CA2790863C (en) | 2010-02-25 | 2018-01-16 | John Clement Preston | Scaffolding |
KR102283127B1 (ko) * | 2018-06-19 | 2021-07-29 | 주식회사 엠디헬스케어 | 류코노스톡속 균주를 포함하는 간 기능 개선용 조성물 |
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ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
ATE12348T1 (de) | 1980-11-10 | 1985-04-15 | Gersonde Klaus Prof Dr | Verfahren zur herstellung von lipid-vesikeln durch ultraschallbehandlung, anwendung des verfahrens und vorrichtung zur durchfuehrung des verfahrens. |
US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
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EP0102324A3 (de) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
US4673641A (en) | 1982-12-16 | 1987-06-16 | Molecular Genetics Research And Development Limited Partnership | Co-aggregate purification of proteins |
US4511502A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4511503A (en) | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4512922A (en) | 1982-12-22 | 1985-04-23 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
US4710473A (en) | 1983-08-10 | 1987-12-01 | Amgen, Inc. | DNA plasmids |
DE3483949D1 (de) | 1983-09-26 | 1991-02-21 | Udo Dr Med Ehrenfeld | Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr. |
EP0143949B1 (de) | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmazeutische Zusammensetzung mit Gehalt an Urokinase |
US4795706A (en) | 1985-01-31 | 1989-01-03 | Eli Lilly And Company | Novel expression control sequences |
ES8800957A1 (es) | 1985-02-22 | 1987-12-01 | Monsanto Co | Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina |
US5453363A (en) * | 1985-10-23 | 1995-09-26 | Boehringer Mannheim Gmbh | Process for the activation of t-PA or Ing after genetic expression in prokaryotes |
AU614137B2 (en) | 1988-06-06 | 1991-08-22 | Takeda Chemical Industries Ltd. | Stabilized fgf composition and production thereof |
DE3835350A1 (de) * | 1988-10-17 | 1990-04-19 | Boehringer Mannheim Gmbh | Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern |
US5332671A (en) * | 1989-05-12 | 1994-07-26 | Genetech, Inc. | Production of vascular endothelial cell growth factor and DNA encoding same |
US5194596A (en) | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
US5304472A (en) | 1992-11-20 | 1994-04-19 | Genentech, Inc. | Method of controlling polypeptide production in bacterial cells |
US5342763A (en) | 1992-11-23 | 1994-08-30 | Genentech, Inc. | Method for producing polypeptide via bacterial fermentation |
PT674506E (pt) | 1992-12-02 | 2001-01-31 | Alkermes Inc | Microsferas contendo hormona de crescimento com libertacao controlada |
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US5663304A (en) | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
US5464815A (en) | 1993-09-08 | 1995-11-07 | Genentech, Inc. | Inhibition of heparin-binding |
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CA2223436A1 (en) | 1995-06-07 | 1996-12-19 | Alkermes Controlled Therapeutics Inc. | Composition for sustained release of human growth hormone |
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US6750044B1 (en) | 1996-10-17 | 2004-06-15 | Genentech, Inc. | Variants of vascular endothelial cell growth factor having antagonistic properties, nucleic acids encoding the same and host cells comprising those nucleic acids |
US6632425B1 (en) * | 1997-03-20 | 2003-10-14 | Human Genome Sciences, Inc. | Chemokine compositions |
DE19735711C2 (de) | 1997-08-18 | 2001-04-26 | Aventis Pharma Gmbh | Verfahren zur Herstellung eines Vorläufers von Insulin oder Insulinderivaten mit korrekt verbundenen Cystinbrücken |
US6653098B1 (en) | 1998-02-23 | 2003-11-25 | G. D. Searle & Co. | Method of producing mouse and human endostatin |
JP4472870B2 (ja) | 1998-03-31 | 2010-06-02 | トンファ ガンテク バイオテクノロジー リミティド | 分子内シャペロン様配列を含有するキメラタンパク質およびインスリン製造へのその適用 |
DK1084136T3 (da) | 1998-06-01 | 2005-01-03 | Genentech Inc | Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi |
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US6783953B1 (en) * | 1998-12-22 | 2004-08-31 | Janssen Pharmaceutica N.V. | Vascular endothelial growth factor-X |
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AU783545B2 (en) | 2000-01-25 | 2005-11-10 | Oklahoma Medical Research Foundation | Universal procedure for refolding recombinant proteins |
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EP1273655A4 (de) * | 2000-03-30 | 2004-08-04 | Takeda Chemical Industries Ltd | Verfahren zur herstellung eines rekombinanten proteins |
IL152804A0 (en) | 2000-05-16 | 2003-06-24 | Bolder Biotechnology Inc | Methods for refolding proteins containing free cysteine residues |
US7611711B2 (en) * | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
WO2002068455A2 (en) | 2001-02-23 | 2002-09-06 | Immunex Corporation | Efficient recovery of correctly refolded proteins |
JP2005524710A (ja) | 2002-05-06 | 2005-08-18 | ジェネンテック・インコーポレーテッド | 骨欠陥の治療へのvegfの用途 |
US7700571B2 (en) | 2002-06-05 | 2010-04-20 | Genentech, Inc. | Compositions and methods for liver growth and liver protection |
ATE364092T1 (de) | 2003-01-09 | 2007-06-15 | Genentech Inc | Reinigung von polypeptiden |
EP1449848A1 (de) | 2003-02-20 | 2004-08-25 | GBF German Research Centre for Biotechnology | Verfahren zur Herstellung von Proteinen aus der Cystine-Knoten-Familie |
WO2005061712A1 (en) | 2003-12-10 | 2005-07-07 | Eli Lilly And Company | Muteins of fibroblast growth factor 21 |
DE102004015965A1 (de) | 2004-04-01 | 2005-10-20 | Aventis Pharma Gmbh | Verfahren zur Gewinnung von Insulinen durch verbesserte Luftbegasung der Faltung |
CA2571781C (en) | 2004-06-28 | 2015-05-12 | Yeda Research And Development Co. Ltd | Chimeric proteins and uses thereof |
KR20070095296A (ko) | 2004-11-22 | 2007-09-28 | 보리안 파마 에이피에스 | Tnf 길항제 |
EP1698637B1 (de) * | 2005-03-03 | 2008-10-15 | Ajinomoto Co., Inc. | Methode zur Verbesserung der Ausbeute bei der Proteinreinigung mittels Gelfiltrationschromatographie und Arginin |
EP1973942B1 (de) | 2005-12-22 | 2011-02-09 | Genentech, Inc. | Rekombinante produktion heparinbindender proteine |
-
2006
- 2006-12-19 EP EP06850998A patent/EP1973942B1/de active Active
- 2006-12-19 AU AU2006343279A patent/AU2006343279B2/en active Active
- 2006-12-19 BR BRPI0621124-0A patent/BRPI0621124A2/pt not_active Application Discontinuation
- 2006-12-19 EP EP10192270A patent/EP2336164A1/de not_active Withdrawn
- 2006-12-19 CA CA2633554A patent/CA2633554C/en active Active
- 2006-12-19 WO PCT/US2006/062320 patent/WO2007130154A2/en active Application Filing
- 2006-12-19 US US11/613,012 patent/US20080032343A1/en not_active Abandoned
- 2006-12-19 KR KR1020087017855A patent/KR101067525B1/ko active IP Right Grant
- 2006-12-19 DE DE602007012412T patent/DE602007012412D1/de active Active
- 2006-12-19 RU RU2008130072/13A patent/RU2385877C1/ru active
- 2006-12-19 MY MYPI20082221A patent/MY143274A/en unknown
- 2006-12-19 NZ NZ568809A patent/NZ568809A/en unknown
- 2006-12-19 JP JP2008547733A patent/JP5036727B2/ja active Active
- 2006-12-19 AT AT06850998T patent/ATE497973T1/de active
- 2006-12-21 AR ARP060105732A patent/AR058625A1/es active IP Right Grant
- 2006-12-22 TW TW095148610A patent/TWI369362B/zh active
-
2008
- 2008-06-05 IL IL191968A patent/IL191968A/en active IP Right Grant
- 2008-12-01 HK HK08113097.7A patent/HK1119188A1/xx unknown
-
2010
- 2010-06-17 US US12/817,382 patent/US20100261888A1/en not_active Abandoned
-
2011
- 2011-08-10 JP JP2011174491A patent/JP2011254831A/ja active Pending
-
2013
- 2013-03-26 US US13/850,641 patent/US8906648B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP1973942B1 (de) | 2011-02-09 |
TWI369362B (en) | 2012-08-01 |
EP2336164A1 (de) | 2011-06-22 |
AU2006343279A1 (en) | 2007-11-15 |
US8906648B2 (en) | 2014-12-09 |
WO2007130154A8 (en) | 2008-04-17 |
MY143274A (en) | 2011-04-15 |
CA2633554A1 (en) | 2007-11-15 |
AU2006343279B2 (en) | 2012-03-29 |
JP2011254831A (ja) | 2011-12-22 |
HK1119188A1 (en) | 2009-07-17 |
RU2008130072A (ru) | 2010-01-27 |
JP2009521232A (ja) | 2009-06-04 |
KR20080087128A (ko) | 2008-09-30 |
IL191968A (en) | 2013-06-27 |
CA2633554C (en) | 2012-11-13 |
JP5036727B2 (ja) | 2012-09-26 |
AR058625A1 (es) | 2008-02-13 |
TW200734351A (en) | 2007-09-16 |
US20080032343A1 (en) | 2008-02-07 |
EP1973942A2 (de) | 2008-10-01 |
NZ568809A (en) | 2011-08-26 |
WO2007130154A2 (en) | 2007-11-15 |
WO2007130154A3 (en) | 2008-06-26 |
ATE497973T1 (de) | 2011-02-15 |
RU2385877C1 (ru) | 2010-04-10 |
US20130217867A1 (en) | 2013-08-22 |
BRPI0621124A2 (pt) | 2011-11-29 |
KR101067525B1 (ko) | 2011-09-27 |
US20100261888A1 (en) | 2010-10-14 |
IL191968A0 (en) | 2008-12-29 |
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