JP4960602B2 - 蛍光観察時の明視野光源及びそれを搭載した手術顕微鏡 - Google Patents
蛍光観察時の明視野光源及びそれを搭載した手術顕微鏡 Download PDFInfo
- Publication number
- JP4960602B2 JP4960602B2 JP2005119082A JP2005119082A JP4960602B2 JP 4960602 B2 JP4960602 B2 JP 4960602B2 JP 2005119082 A JP2005119082 A JP 2005119082A JP 2005119082 A JP2005119082 A JP 2005119082A JP 4960602 B2 JP4960602 B2 JP 4960602B2
- Authority
- JP
- Japan
- Prior art keywords
- light source
- surgical microscope
- bright field
- affected area
- field light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000002093 peripheral effect Effects 0.000 claims description 24
- 230000005284 excitation Effects 0.000 claims description 19
- 239000004065 semiconductor Substances 0.000 claims description 12
- 230000001678 irradiating effect Effects 0.000 claims description 4
- 239000003504 photosensitizing agent Substances 0.000 claims 1
- 238000005286 illumination Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 6
- 230000000007 visual effect Effects 0.000 description 4
- 238000012423 maintenance Methods 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 2
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- VSEIDZLLWQQJGK-CHOZPQDDSA-N CCC1=C(C)C2=N\C\1=C/C1=C(C)C(C(O)=O)=C(N1)\C(CC(=O)N[C@@H](CC(O)=O)C(O)=O)=C1/N=C(/C=C3\N/C(=C\2)C(C=C)=C3C)[C@@H](C)[C@@H]1CCC(O)=O Chemical compound CCC1=C(C)C2=N\C\1=C/C1=C(C)C(C(O)=O)=C(N1)\C(CC(=O)N[C@@H](CC(O)=O)C(O)=O)=C1/N=C(/C=C3\N/C(=C\2)C(C=C)=C3C)[C@@H](C)[C@@H]1CCC(O)=O VSEIDZLLWQQJGK-CHOZPQDDSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
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- 239000000835 fiber Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 229950010924 talaporfin Drugs 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
- A61B2090/309—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure using white LEDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/20—Surgical microscopes characterised by non-optical aspects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/062—LED's
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Optics & Photonics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microscoopes, Condenser (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005119082A JP4960602B2 (ja) | 2005-04-15 | 2005-04-15 | 蛍光観察時の明視野光源及びそれを搭載した手術顕微鏡 |
| US11/401,843 US20060232855A1 (en) | 2005-04-15 | 2006-04-12 | Bright-field light source for fluorescence observation and surgical microscope with bright-field light source |
| DE102006017799A DE102006017799A1 (de) | 2005-04-15 | 2006-04-18 | Hellfeld-Lichtquelle zur Beobachtung der Fluoreszenz und Chirurgiemikroskop mit Hellfeld-Lichtquelle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005119082A JP4960602B2 (ja) | 2005-04-15 | 2005-04-15 | 蛍光観察時の明視野光源及びそれを搭載した手術顕微鏡 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008082038A Division JP4960915B2 (ja) | 2008-03-26 | 2008-03-26 | 手術顕微鏡用アタッチメント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006296516A JP2006296516A (ja) | 2006-11-02 |
| JP2006296516A5 JP2006296516A5 (enExample) | 2008-05-08 |
| JP4960602B2 true JP4960602B2 (ja) | 2012-06-27 |
Family
ID=37055675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005119082A Expired - Fee Related JP4960602B2 (ja) | 2005-04-15 | 2005-04-15 | 蛍光観察時の明視野光源及びそれを搭載した手術顕微鏡 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20060232855A1 (enExample) |
| JP (1) | JP4960602B2 (enExample) |
| DE (1) | DE102006017799A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4800248B2 (ja) * | 2007-03-23 | 2011-10-26 | 三鷹光器株式会社 | 手術顕微鏡システム |
| DE102007041003A1 (de) * | 2007-05-31 | 2008-12-04 | Carl Zeiss Surgical Gmbh | Operationsmikroskop mit Beleuchtungseinrichtung |
| DE102008045671A1 (de) * | 2008-09-03 | 2010-03-04 | Bundesrepublik Deutschland, vertreten durch den Präsidenten der Bundesanstalt für Geowissenschaften und Rohstoffe | Fluoreszenz-Mikroskop, insbesondere für Gesteinsuntersuchungen |
| DE102009025127A1 (de) | 2009-06-17 | 2010-12-23 | Carl Zeiss Surgical Gmbh | Beleuchtungseinrichtung für ein optisches Beobachtungsgerät |
| WO2016103643A1 (en) | 2014-12-25 | 2016-06-30 | Sony Corporation | Medical imaging system, illumination device, and method |
| CN104570311A (zh) * | 2014-12-26 | 2015-04-29 | 中国科学院苏州生物医学工程技术研究所 | 基于多谱段led光源的荧光显微镜 |
| DE102015119590B4 (de) | 2015-11-12 | 2023-02-09 | Carsten Jung | Beleuchtungsanordnung und Mikroskop |
| JP6619996B2 (ja) * | 2015-11-24 | 2019-12-11 | 三鷹光器株式会社 | 手術用立体観察装置 |
| WO2020133110A1 (zh) * | 2018-12-27 | 2020-07-02 | 深圳市奥沃医学新技术发展有限公司 | 光野灯组件、光野指示器及放疗设备 |
| WO2021211668A1 (en) | 2020-04-14 | 2021-10-21 | The Regents Of The University Of California | Method and system for selective spectral illumination for optical image guided surgery |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3015082B2 (ja) * | 1990-08-28 | 2000-02-28 | オリンパス光学工業株式会社 | 透過及び落射同時観察可能な顕微鏡及びその自動調光方法 |
| US5325231A (en) * | 1991-03-22 | 1994-06-28 | Olympus Optical Co., Ltd. | Microscope illuminating apparatus |
| DE4320579C2 (de) * | 1992-06-15 | 2000-06-15 | Topcon Corp | Operationsmikroskop |
| JP3539436B2 (ja) * | 1993-12-27 | 2004-07-07 | オリンパス株式会社 | 走査型レーザ顕微鏡装置 |
| JP3872856B2 (ja) * | 1997-01-23 | 2007-01-24 | オリンパス株式会社 | 蛍光顕微鏡 |
| EP1097935B1 (en) * | 1998-07-10 | 2003-12-03 | Meiji Seika Kaisha Ltd. | X-ray intercepting metal complexes of chlorin derivatives |
| JP2000089124A (ja) * | 1998-09-14 | 2000-03-31 | Nikon Corp | 複合顕微鏡 |
| DE19845603C2 (de) * | 1998-10-05 | 2000-08-17 | Leica Microsystems | Beleuchtungseinrichtung für ein Mikroskop |
| DE10108254A1 (de) * | 2001-02-21 | 2002-08-22 | Leica Microsystems | Optische Betrachtungseinrichtung mit Vorrichtung zur partiellen Reduktion der Intensität der Beleuchtung |
| PL373724A1 (en) * | 2001-08-23 | 2005-09-05 | Yukiyasu Okumura | Color temperature-regulable led light |
| JP2003315678A (ja) * | 2002-04-22 | 2003-11-06 | Mitsutoyo Corp | リング照明装置 |
| US7580185B2 (en) * | 2002-08-28 | 2009-08-25 | Carl Zeiss Surgical Gmbh | Microscopy system, microscopy method and a method of treating an aneurysm |
| DE10242983B4 (de) * | 2002-09-17 | 2016-01-28 | Leica Microsystems Gmbh | Ophthalmo-Operationsmikroskop mit Objektbeleuchtung |
| JP4354207B2 (ja) * | 2003-04-15 | 2009-10-28 | オリンパス株式会社 | 顕微鏡装置 |
| DE10339619A1 (de) * | 2003-08-28 | 2005-03-24 | Leica Microsystems (Schweiz) Ag | Stereomikroskop mit integrierter Auflicht-Beleuchtungseinrichtung |
| JP2007528500A (ja) * | 2004-03-11 | 2007-10-11 | ザ・ゼネラル・ホスピタル・コーポレーション | 蛍光タンパク質を使用する断層撮影イメージングのための方法およびシステム |
-
2005
- 2005-04-15 JP JP2005119082A patent/JP4960602B2/ja not_active Expired - Fee Related
-
2006
- 2006-04-12 US US11/401,843 patent/US20060232855A1/en not_active Abandoned
- 2006-04-18 DE DE102006017799A patent/DE102006017799A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20060232855A1 (en) | 2006-10-19 |
| JP2006296516A (ja) | 2006-11-02 |
| DE102006017799A1 (de) | 2006-10-19 |
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