JP4917893B2 - 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法 - Google Patents

作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法 Download PDF

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JP4917893B2
JP4917893B2 JP2006543959A JP2006543959A JP4917893B2 JP 4917893 B2 JP4917893 B2 JP 4917893B2 JP 2006543959 A JP2006543959 A JP 2006543959A JP 2006543959 A JP2006543959 A JP 2006543959A JP 4917893 B2 JP4917893 B2 JP 4917893B2
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dosage form
agent
core
sheath
coextrusion
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JP2007513960A (ja
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フラス，ロバート，ピー．
マッセリンク，ジョン，ケイ．
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ユーロ−セルティーク エス．エイ．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2006543959A 2003-12-09 2004-12-08 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法 Expired - Lifetime JP4917893B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52855003P 2003-12-09 2003-12-09
US60/528,550 2003-12-09
PCT/US2004/041154 WO2005055981A2 (en) 2003-12-09 2004-12-08 Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2011020960A Division JP5473958B2 (ja) 2003-12-09 2011-02-02 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法
JP2011272389A Division JP2012082214A (ja) 2003-12-09 2011-12-13 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法

Publications (2)

Publication Number Publication Date
JP2007513960A JP2007513960A (ja) 2007-05-31
JP4917893B2 true JP4917893B2 (ja) 2012-04-18

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JP2006543959A Expired - Lifetime JP4917893B2 (ja) 2003-12-09 2004-12-08 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法
JP2011020960A Expired - Lifetime JP5473958B2 (ja) 2003-12-09 2011-02-02 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法
JP2011272389A Pending JP2012082214A (ja) 2003-12-09 2011-12-13 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法

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JP2011020960A Expired - Lifetime JP5473958B2 (ja) 2003-12-09 2011-02-02 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法
JP2011272389A Pending JP2012082214A (ja) 2003-12-09 2011-12-13 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法

Country Status (13)

Country Link
US (1) US20070269505A1 (enExample)
EP (1) EP1691892B1 (enExample)
JP (3) JP4917893B2 (enExample)
AT (1) ATE355103T1 (enExample)
CA (1) CA2548834C (enExample)
CY (1) CY1106600T1 (enExample)
DE (1) DE602004005076T2 (enExample)
DK (1) DK1691892T3 (enExample)
ES (1) ES2281851T3 (enExample)
PL (1) PL1691892T3 (enExample)
PT (1) PT1691892E (enExample)
SI (1) SI1691892T1 (enExample)
WO (1) WO2005055981A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012082214A (ja) * 2003-12-09 2012-04-26 Euro-Celtique Sa 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法

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Publication number Priority date Publication date Assignee Title
JP2012082214A (ja) * 2003-12-09 2012-04-26 Euro-Celtique Sa 作用薬及び逆作用薬を含有する不正使用防止共押出剤型、及びその製造方法

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Publication number Publication date
PT1691892E (pt) 2007-05-31
JP2007513960A (ja) 2007-05-31
DE602004005076D1 (de) 2007-04-12
DE602004005076T2 (de) 2007-11-15
JP5473958B2 (ja) 2014-04-16
US20070269505A1 (en) 2007-11-22
CA2548834A1 (en) 2005-06-23
PL1691892T3 (pl) 2007-07-31
CA2548834C (en) 2009-08-11
ES2281851T3 (es) 2007-10-01
CY1106600T1 (el) 2012-01-25
WO2005055981A3 (en) 2005-08-11
WO2005055981A2 (en) 2005-06-23
JP2011126895A (ja) 2011-06-30
ATE355103T1 (de) 2006-03-15
SI1691892T1 (sl) 2007-08-31
DK1691892T3 (da) 2007-06-25
EP1691892A2 (en) 2006-08-23
EP1691892B1 (en) 2007-02-28
JP2012082214A (ja) 2012-04-26

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