JP4896718B2 - 微生物によるｌ−アスコルビン酸の製造 - Google Patents

微生物によるｌ−アスコルビン酸の製造 Download PDF

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Publication number
JP4896718B2
JP4896718B2 JP2006522868A JP2006522868A JP4896718B2 JP 4896718 B2 JP4896718 B2 JP 4896718B2 JP 2006522868 A JP2006522868 A JP 2006522868A JP 2006522868 A JP2006522868 A JP 2006522868A JP 4896718 B2 JP4896718 B2 JP 4896718B2
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JP
Japan
Prior art keywords
cells
ascorbic acid
seq
sorbosone
polynucleotide
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Japanese (ja)
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JP2007502102A5 (enExample
JP2007502102A (ja
Inventor
ベリー，アラン
リー，コニー
マイヤー，アン・フランソワ
雅子 新城
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DSM IP Assets BV
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DSM IP Assets BV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2006522868A 2003-08-14 2004-08-16 微生物によるｌ−アスコルビン酸の製造 Expired - Fee Related JP4896718B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03017677 2003-08-14
EP03017677.0 2003-08-14
PCT/CH2004/000511 WO2005017159A2 (en) 2003-08-14 2004-08-16 Microbial production of l-ascorbic acid

Publications (3)

Publication Number Publication Date
JP2007502102A JP2007502102A (ja) 2007-02-08
JP2007502102A5 JP2007502102A5 (enExample) 2007-10-04
JP4896718B2 true JP4896718B2 (ja) 2012-03-14

Family

ID=34178381

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006522868A Expired - Fee Related JP4896718B2 (ja) 2003-08-14 2004-08-16 微生物によるｌ−アスコルビン酸の製造

Country Status (9)

Country Link
US (3) US7700723B2 (enExample)
EP (2) EP2348113B1 (enExample)
JP (1) JP4896718B2 (enExample)
KR (1) KR101311562B1 (enExample)
CN (2) CN1882691B (enExample)
BR (1) BRPI0413542A (enExample)
EA (1) EA009287B1 (enExample)
ES (2) ES2593811T3 (enExample)
WO (2) WO2005017159A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101151365B (zh) * 2005-02-11 2012-05-23 帝斯曼知识产权资产管理有限公司 基因sms02
WO2006084645A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene rcs 10
US20090023191A1 (en) * 2005-02-11 2009-01-22 Bastien Chevreux Gene RCS 23
WO2006084724A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene rcs 28
EP1846440A1 (en) * 2005-02-11 2007-10-24 DSMIP Assets B.V. Gene for coenzyme pqq synthesis protein b from gluconobacter oxydans
EP2308965A1 (en) 2005-02-11 2011-04-13 DSM IP Assets B.V. Fermentative vitamin C production
WO2006084643A2 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene vcs 07
EP1846565A1 (en) * 2005-02-11 2007-10-24 DSMIP Assets B.V. Gene rcs 21
EP1846551A1 (en) * 2005-02-11 2007-10-24 DSMIP Assets B.V. Gene rcs 25
CN101316929A (zh) 2005-09-08 2008-12-03 帝斯曼知识产权资产管理有限公司 新颖的基因sms 37
CN101292025A (zh) 2005-09-09 2008-10-22 帝斯曼知识产权资产管理有限公司 来自Gluconobacter oxydans的NADP依赖性葡糖脱氢酶
WO2007028611A2 (en) * 2005-09-09 2007-03-15 Dsm Ip Assets B.V. Process for biomass production using a microorganism with a disrupted glucose-dehydrogenase gene (gms 01)
FR2906817B1 (fr) * 2006-10-04 2012-04-06 Gervais Danone Sa Procede de culture pour favoriser la production de vitamine k2 par les bacteries lactiques et ses applications a la preparation de produits alimentaires
EP1918382A1 (en) * 2006-11-02 2008-05-07 DSMIP Assets B.V. Semi-continuous cascade fermentation process for pantothenate production
EP1918383A1 (en) * 2006-11-02 2008-05-07 DSMIP Assets B.V. Semi-continuous fermentation process for pantothenate production
WO2009087223A1 (en) * 2008-01-10 2009-07-16 Dsm Ip Assets B.V. Novel gene sms 44
CN103073601B (zh) * 2013-02-01 2015-08-19 东北制药集团股份有限公司 一种2-酮基-l-古龙酸溶液加晶种的可控浓缩结晶方法
NZ743055A (en) 2013-03-08 2020-03-27 Xyleco Inc Equipment protecting enclosures
WO2014160818A2 (en) 2013-03-27 2014-10-02 Sample Technologies, Inc. Recombinant phage and bacterial detection methods
EP3011062A4 (en) * 2013-06-19 2017-06-14 Sample6 Technologies Inc. Phage-based bacterial detection assay
EP3036250A1 (en) * 2013-08-23 2016-06-29 Boehringer Ingelheim RCV GmbH & Co KG Microparticles for cell disruption and/or biomolecule recovery
AU2015236045B2 (en) * 2014-03-25 2021-09-23 Ginkgo Bioworks, Inc. Methods and genetic systems for cell engineering
CN116053017B (zh) * 2022-11-04 2023-08-22 医波(厦门)科技有限公司 一种复合磁性微球及其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082785A (en) 1987-01-30 1992-01-21 Hoffmann-La Roche Inc. Biosynthesis of 2 keto-l-gulonic acid
EP0373181B1 (en) 1988-01-14 1995-11-08 F. Hoffmann-La Roche Ag Novel coenzyme independent l-sorbosone dehydrogenase
EP0476442B1 (en) * 1990-09-17 1999-06-02 F. Hoffmann-La Roche Ag L-gulono-gamma-lactone dehydrogenase
US5376544A (en) 1992-09-08 1994-12-27 Rutgers The State University Of New Jersey Enzymes for the production of 2-keto-L-gulonic acid
WO1997004101A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Enzym geeignet zur oxidation von cyclitolen und ihren derivaten
EP0922759B1 (en) * 1997-12-01 2004-01-28 F. Hoffmann-La Roche Ag Aldehyde dehydrogenase
US20020012979A1 (en) * 1998-06-08 2002-01-31 Alan Berry Vitamin c production in microorganisms and plants
GB0119864D0 (en) * 2001-08-15 2001-10-10 Cerestar Holding Bv Process for the manufacture of 2-keto-L-gulonic acid
WO2003089634A1 (en) * 2002-04-22 2003-10-30 Dsm Ip Assets B.V. Aldehyde dehydrogenase ii
AU2003274096A1 (en) * 2002-06-06 2003-12-22 Dsm Ip Assets B.V. Aldehyde dehydrogenase
AU2003299104A1 (en) 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Aldehyde dehydrogenase gene
CN100347309C (zh) * 2002-09-27 2007-11-07 帝斯曼知识产权资产管理有限公司 生产维生素c的方法
JP4471841B2 (ja) 2002-09-27 2010-06-02 ディーエスエム アイピー アセッツ ビー．ブイ． 微生物によるビタミンｃの製造
ATE469976T1 (de) 2004-01-30 2010-06-15 Dsm Ip Assets Bv Mikrobielle vitamin-c-produktion
US20080226126A1 (en) * 2005-01-31 2008-09-18 Yoshinori Ohno Object-Tracking Apparatus, Microscope System, and Object-Tracking Program
EP2308965A1 (en) 2005-02-11 2011-04-13 DSM IP Assets B.V. Fermentative vitamin C production

Also Published As

Publication number Publication date
EA009287B1 (ru) 2007-12-28
EA200600408A1 (ru) 2006-08-25
WO2005017172A1 (en) 2005-02-24
US8338144B2 (en) 2012-12-25
KR101311562B1 (ko) 2013-09-26
US20130217080A1 (en) 2013-08-22
BRPI0413542A (pt) 2006-10-17
EP2348113B1 (en) 2016-06-29
JP2007502102A (ja) 2007-02-08
ES2593811T3 (es) 2016-12-13
CN1882691B (zh) 2014-05-28
EP2348113A2 (en) 2011-07-27
EP1664303A2 (en) 2006-06-07
CN104004776A (zh) 2014-08-27
CN1882691A (zh) 2006-12-20
EP2348113A3 (en) 2012-11-14
WO2005017159A3 (en) 2005-11-03
US7700723B2 (en) 2010-04-20
EP1664303B1 (en) 2013-04-24
KR20060064629A (ko) 2006-06-13
US20100203598A1 (en) 2010-08-12
US20070184534A1 (en) 2007-08-09
ES2421294T3 (es) 2013-08-30
WO2005017159A2 (en) 2005-02-24

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