JP4855626B2 - 製薬分野における新規なアミノチオールエステル誘導体 - Google Patents

製薬分野における新規なアミノチオールエステル誘導体 Download PDF

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JP4855626B2
JP4855626B2 JP2002500835A JP2002500835A JP4855626B2 JP 4855626 B2 JP4855626 B2 JP 4855626B2 JP 2002500835 A JP2002500835 A JP 2002500835A JP 2002500835 A JP2002500835 A JP 2002500835A JP 4855626 B2 JP4855626 B2 JP 4855626B2
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cells
methyl
compound
diseases
carbon atoms
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JP2003535076A (ja
JP2003535076A5 (enExample
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ギー・フルネ
アントニー・ジェラール・クアシュ
ジャック・ゴール
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Centre National de la Recherche Scientifique CNRS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/04—Antipruritics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/22—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2002500835A 2000-05-31 2001-05-31 製薬分野における新規なアミノチオールエステル誘導体 Expired - Lifetime JP4855626B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR00/07029 2000-05-31
FR0007029A FR2809727B1 (fr) 2000-05-31 2000-05-31 Nouveaux composes aminothiolesters, compositions pharmaceutiques et cosmetiques les contenant et utilisations
PCT/FR2001/001694 WO2001092220A1 (fr) 2000-05-31 2001-05-31 Composes aminothiolesters, compositions pharmaceutiques et cosmetiques les contenant et utilisations

Publications (3)

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JP2003535076A JP2003535076A (ja) 2003-11-25
JP2003535076A5 JP2003535076A5 (enExample) 2011-10-27
JP4855626B2 true JP4855626B2 (ja) 2012-01-18

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JP2002500835A Expired - Lifetime JP4855626B2 (ja) 2000-05-31 2001-05-31 製薬分野における新規なアミノチオールエステル誘導体

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Country Link
US (1) US8026231B2 (enExample)
EP (1) EP1296946B1 (enExample)
JP (1) JP4855626B2 (enExample)
AR (1) AR028122A1 (enExample)
AT (1) ATE264839T1 (enExample)
AU (1) AU2001274171A1 (enExample)
DE (1) DE60102925T2 (enExample)
ES (1) ES2219530T3 (enExample)
FR (1) FR2809727B1 (enExample)
WO (1) WO2001092220A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2983492B1 (fr) * 2011-12-06 2015-10-30 Advanced Biodesign Procede ex vivo de purge tumorale d'un echantillon biologique
PL3362094T3 (pl) * 2015-10-15 2021-10-11 Advanced Biodesign Kombinacja zawierająca związek tioaminoestrowy lub jego farmaceutycznie dopuszczalną sól oraz związek mogący zwiększyć poziom h2o2 w komórkach nowotworowych osobnika
LT3362056T (lt) 2015-10-15 2021-05-10 Advanced Biodesign Aminotiolesterio junginiai arba jų farmaciniu požiūriu priimtinos druskos, skirti naudoti vėžio gydyme
FR3047734B1 (fr) * 2016-02-17 2019-09-06 Advanced Biodesign Procede de preparation de composes aminothiolester et leurs sels
US20220265845A1 (en) * 2019-07-31 2022-08-25 Advanced Biodesign Aminothiolester compounds and uses thereof
EP4035666A1 (en) 2021-01-29 2022-08-03 Advanced Biodesign Aminothiolester compound or derivative thereof for use as an immunomodulatory agent
FR3119314B1 (fr) 2021-01-29 2025-01-10 Advanced Biodesign Nanocapsule lipidique comprenant au moins un composé aminothiolester ou un de ses dérivés pharmaceutiquement acceptable
WO2025229179A1 (en) 2024-05-03 2025-11-06 Advanced Biodesign Use of aminothiolester compounds in combination with hypomethylating agents (hma) for the prevention and treatment of cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0797350A (ja) * 1993-08-02 1995-04-11 Mitsubishi Chem Corp ベンゾイルアセチレン誘導体
JP2000001471A (ja) * 1998-04-01 2000-01-07 Galderma Res & Dev Snc ６，８―ジメルカプトオクタン酸誘導体及びそれを含有する医薬組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051528A (en) * 1990-04-24 1991-09-24 Eastman Kodak Company Recovery process for ethylene glycol and dimethylterephthalate
FR2761606B1 (fr) * 1997-04-08 1999-05-14 Cird Galderma Utilisation de derives aminothiolesters dans le domaine pharmaceutique
KR100488985B1 (ko) 1997-12-02 2005-05-11 하인리히 스무다 폴리에틸렌테레프탈레이트 폐기물로부터 테레프탈산 및 에틸렌글리콜을 회수하는 방법
EP1227075B1 (en) 1999-10-22 2009-07-29 Teijin Limited Method for separating and recovering dimethyl terephthalate and ethylene glycol from polyester waste
JP3808672B2 (ja) * 1999-11-26 2006-08-16 東洋製罐株式会社 回収ポリエチレンテレフタレート粉砕品からのテレフタル酸の工業的回収方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0797350A (ja) * 1993-08-02 1995-04-11 Mitsubishi Chem Corp ベンゾイルアセチレン誘導体
JP2000001471A (ja) * 1998-04-01 2000-01-07 Galderma Res & Dev Snc ６，８―ジメルカプトオクタン酸誘導体及びそれを含有する医薬組成物

Also Published As

Publication number Publication date
DE60102925T2 (de) 2005-04-07
FR2809727A1 (fr) 2001-12-07
DE60102925D1 (de) 2004-05-27
WO2001092220A1 (fr) 2001-12-06
JP2003535076A (ja) 2003-11-25
EP1296946B1 (fr) 2004-04-21
AU2001274171A1 (en) 2001-12-11
AR028122A1 (es) 2003-04-23
US20070032476A1 (en) 2007-02-08
ATE264839T1 (de) 2004-05-15
ES2219530T3 (es) 2004-12-01
EP1296946A1 (fr) 2003-04-02
FR2809727B1 (fr) 2002-07-26
US8026231B2 (en) 2011-09-27

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