JP4843044B2 - 非蛍光性エネルギー移動 - Google Patents
非蛍光性エネルギー移動 Download PDFInfo
- Publication number
- JP4843044B2 JP4843044B2 JP2008533937A JP2008533937A JP4843044B2 JP 4843044 B2 JP4843044 B2 JP 4843044B2 JP 2008533937 A JP2008533937 A JP 2008533937A JP 2008533937 A JP2008533937 A JP 2008533937A JP 4843044 B2 JP4843044 B2 JP 4843044B2
- Authority
- JP
- Japan
- Prior art keywords
- carboxy
- moiety
- hexachlorofluorescein
- acceptor
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72420205P | 2005-10-05 | 2005-10-05 | |
| US60/724,202 | 2005-10-05 | ||
| PCT/EP2006/009646 WO2007039301A2 (en) | 2005-10-05 | 2006-10-05 | Non-fluorescent energy transfer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009512837A JP2009512837A (ja) | 2009-03-26 |
| JP2009512837A5 JP2009512837A5 (enExample) | 2009-09-03 |
| JP4843044B2 true JP4843044B2 (ja) | 2011-12-21 |
Family
ID=37574999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008533937A Expired - Fee Related JP4843044B2 (ja) | 2005-10-05 | 2006-10-05 | 非蛍光性エネルギー移動 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7741467B2 (enExample) |
| EP (1) | EP1934374B1 (enExample) |
| JP (1) | JP4843044B2 (enExample) |
| CN (1) | CN101321878B (enExample) |
| AT (1) | ATE519863T1 (enExample) |
| CA (1) | CA2624917C (enExample) |
| ES (1) | ES2371088T3 (enExample) |
| WO (1) | WO2007039301A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7745125B2 (en) | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| FI20070163A0 (fi) * | 2007-02-27 | 2007-02-27 | Hidex Oy | Parannettu homogeeninen luminesenssibiotesti |
| JP2010525333A (ja) * | 2007-04-18 | 2010-07-22 | ベクトン・ディキンソン・アンド・カンパニー | Sersナノタグを用いる分析法 |
| US8206929B2 (en) * | 2009-01-07 | 2012-06-26 | Roche Molecular Systems, Inc. | Nucleic acid amplification with allele-specific suppression of sequence variants |
| WO2010095033A1 (en) * | 2009-02-20 | 2010-08-26 | Perkinelmer Biosignal, Inc. | Multiplex assay methods and compositions |
| WO2010101947A2 (en) * | 2009-03-02 | 2010-09-10 | Cooperative Diagnostics, Llc | Rapid oligo probes |
| US8674080B2 (en) | 2009-04-09 | 2014-03-18 | Roche Molecular Systems, Inc. | Dye composition for liquid transfer control |
| EP4098753A1 (en) * | 2014-10-23 | 2022-12-07 | Ricardo Mancebo | Reagents and methods for isothermal chain reaction |
| US9745618B2 (en) | 2014-11-19 | 2017-08-29 | Roche Molecular Systems, Inc. | Photoblocked probes and methods for sequential detection of nucleic acids |
| US9920381B2 (en) | 2014-12-02 | 2018-03-20 | Roche Molecular Systems, Inc. | Compositions and methods for detecting MECC-containing methicillin-resistant Staphylococcus aureus |
| WO2017153566A1 (en) | 2016-03-11 | 2017-09-14 | Roche Diagnostics Gmbh | Compositions and methods for detection of zika virus |
| WO2017202894A1 (en) | 2016-05-27 | 2017-11-30 | Roche Diagnostics Gmbh | Compositions and methods for detection of trichomonas vaginalis |
| US10612101B2 (en) | 2016-05-27 | 2020-04-07 | Roche Molecular Systems, Inc. | Compositions and methods for detection of Mycoplasma genitalium |
| EP3465847B1 (en) * | 2016-06-03 | 2025-08-06 | The General Hospital Corporation | System and method for micro laser particles |
| IL291323B2 (en) | 2016-07-15 | 2023-09-01 | Am Chemicals Llc | Solid non-nucleoside supports and phosphoramidite building blocks for oligonucleotide synthesis |
| WO2018023094A1 (en) | 2016-07-29 | 2018-02-01 | Juno Therapeutics, Inc. | Methods for assessing the presence or absence of replication competent virus |
| US10443095B2 (en) | 2016-08-02 | 2019-10-15 | Roche Molecular Systems, Inc. | Helper oligonucleotide for improved efficiency of amplification and detection/quantitation of nucleic acids |
| US10793923B2 (en) | 2016-11-09 | 2020-10-06 | Roche Molecular Systems, Inc. | Compositions and methods for detection of BK virus |
| US10760137B2 (en) | 2017-07-18 | 2020-09-01 | Roche Molecular Systems, Inc. | Compositions and methods for detection of Babesia |
| WO2019063661A1 (en) | 2017-09-29 | 2019-04-04 | Roche Diagnostics Gmbh | COMPOSITIONS AND METHODS FOR THE DETECTION OF TRICHOMONAS VAGINALIS |
| JP2021511802A (ja) | 2018-01-31 | 2021-05-13 | ジュノー セラピューティクス インコーポレイテッド | 複製可能ウイルスの存在または非存在を評価するための方法および試薬 |
| US11604186B2 (en) * | 2018-10-17 | 2023-03-14 | Molecular Devices (Austria) GmbH | Real time western blot assays utilizing fluorescence resonance energy transfer (FRET) |
| CN113166802A (zh) | 2018-12-03 | 2021-07-23 | 豪夫迈·罗氏有限公司 | 用于检测耳道假丝酵母菌的组合物和方法 |
| WO2020221915A1 (en) | 2019-05-02 | 2020-11-05 | F. Hoffmann-La Roche Ag | UTILIZATION OF dITP FOR PREFERENTIAL/SELECTIVE AMPLIFICATION OF RNA VERSUS DNA TARGETS BASED ON STRAND-SEPARATION TEMPERATURE |
| JP7592027B2 (ja) | 2019-05-07 | 2024-11-29 | エフ. ホフマン-ラ ロシュ アーゲー | ナイセリア・ゴノレア(Neisseria Gonorroheae)を検出するための組成物および方法 |
| JP7649285B2 (ja) | 2019-07-25 | 2025-03-19 | エフ. ホフマン-ラ ロシュ アーゲー | エプスタイン・バーウイルス(ebv)を検出するための組成物および方法 |
| ES3039650T3 (en) | 2019-08-27 | 2025-10-23 | Hoffmann La Roche | Compositions and methods for amplification and detection of hepatitis b virus rna, including hbv rna transcribed from cccdna |
| US11441167B2 (en) | 2019-11-20 | 2022-09-13 | Roche Molecular Systems, Inc. | Compositions and methods for rapid identification and phenotypic antimicrobial susceptibility testing of bacteria and fungi |
| ES2991814T3 (es) | 2019-12-27 | 2024-12-05 | Hoffmann La Roche | Composiciones y procedimientos para detectar Staphylococcus aureus resistente a la meticilina |
| US20220356537A1 (en) | 2019-12-31 | 2022-11-10 | Roche Molecular Systems, Inc. | Quantitative pcr screening of inducible prophage from bacterial isolates |
| CA3166337A1 (en) | 2020-03-09 | 2021-09-16 | F. Hoffmann-La Roche Ag | Compositions and methods for detecting severe acute respiratory syndrome coronavirus 2 (sars-cov-2), influenza a and influenza b |
| WO2022029157A2 (en) | 2020-08-06 | 2022-02-10 | F. Hoffmann-La Roche Ag | Compositions and methods for the detection of severe acute respiratory syndrome coronavirus 2 (sars-2), influenza a, and influenza b |
| CN112630198A (zh) * | 2020-09-15 | 2021-04-09 | 北京工业大学 | 一种基于回音壁模式光学微腔的传感检测方法 |
| US20240102110A1 (en) | 2020-12-04 | 2024-03-28 | Roche Molecular Systems, Inc. | Compositions and methods for detection of malaria |
| US20220205020A1 (en) | 2020-12-30 | 2022-06-30 | Roche Molecular Systems, Inc. | Compositions and methods for detection of bacteria and fungi associated with bacterial and candida vaginosis |
| EP4288567A1 (en) | 2021-02-05 | 2023-12-13 | F. Hoffmann-La Roche AG | Compositions and methods for detection of human parainfluenza viruses 1-4 (hpiv 1-4) |
| US20220290221A1 (en) | 2021-03-15 | 2022-09-15 | Roche Molecular Systems, Inc. | Compositions and methods for detecting severe acute respiratory syndrome coronavirus 2 (sars-cov-2) variants having spike protein mutations |
| JP2024517835A (ja) | 2021-05-06 | 2024-04-23 | エフ. ホフマン-ラ ロシュ アーゲー | 二重標的アッセイによりデルタ型肝炎ウイルスを検出するための組成物及び方法 |
| WO2023079032A1 (en) | 2021-11-05 | 2023-05-11 | F. Hoffmann-La Roche Ag | Compositions and methods for detection of malaria |
| EP4437142A1 (en) | 2021-11-22 | 2024-10-02 | F. Hoffmann-La Roche AG | Compositions and methods for detecting vana and/or vanb genes associated with multidrug resistance |
| CN118434883A (zh) | 2021-12-24 | 2024-08-02 | 豪夫迈·罗氏有限公司 | Lamp扩增产物的改进检测 |
| EP4547873A1 (en) | 2022-06-30 | 2025-05-07 | F. Hoffmann-La Roche AG | Compositions and methods for detecting lymphogranuloma venereum (lgv) serovars of chlamydia trachomatis |
| EP4577674A1 (en) | 2022-08-24 | 2025-07-02 | F. Hoffmann-La Roche AG | Compositions and methods for detecting monkeypox virus |
| CN120418449A (zh) | 2022-12-25 | 2025-08-01 | 豪夫迈·罗氏有限公司 | 用于检测耐碳青霉烯的醋酸钙不动杆菌-鲍氏不动杆菌(crab)的组合物和方法 |
| EP4642924A1 (en) | 2022-12-28 | 2025-11-05 | F. Hoffmann-La Roche AG | Digital pcr assay designs for multiple hepatitis b virus gene targets and non-extendable blocker oligonucleotides therefor |
| CN120731278A (zh) | 2023-02-25 | 2025-09-30 | 豪夫迈·罗氏有限公司 | 用于念珠菌属物种检测的组合物和方法 |
| WO2024184165A1 (en) | 2023-03-03 | 2024-09-12 | F. Hoffmann-La Roche Ag | Compositions and methods for the detection of group b streptococcus ( streptococcus agalactiae) and clindamycin resistance gene determinants |
| WO2025027080A1 (en) | 2023-08-03 | 2025-02-06 | F. Hoffmann-La Roche Ag | Use of 5'-tailed long primers to improve amplification performance when targeting short primer-binding sites |
| WO2025202488A1 (en) | 2024-03-28 | 2025-10-02 | Roche Diagnostics Gmbh | Enhancer of nucleic acid amplification |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| DE3071373D1 (en) | 1980-10-27 | 1986-03-06 | Syva Co | Novel ether substituted fluorescein compounds as fluorescers and quenchers |
| EP0144914A3 (en) | 1983-12-12 | 1986-08-13 | Miles Inc. | Hybridization assay employing labeled pairs of hybrid binding reagents |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| EP0476545B1 (en) * | 1990-09-14 | 1997-05-07 | Tosoh Corporation | Method of and kit for immunoassay |
| DE69231853T2 (de) | 1991-11-07 | 2001-09-13 | Nanotronics, Inc. | Hybridisierung von mit chromophoren und fluorophoren konjugierten polynukleotiden zur erzeugung eines donor-zu-donor energietransfersystems |
| US6821727B1 (en) | 1993-11-15 | 2004-11-23 | Applera Corporation | Hybridization assay using self-quenching fluorescence probe |
| US6028190A (en) | 1994-02-01 | 2000-02-22 | The Regents Of The University Of California | Probes labeled with energy transfer coupled dyes |
| US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| ATE198511T1 (de) | 1994-04-29 | 2001-01-15 | Perkin Elmer Corp | Verfahren und vorrichtung zur echtzeiterfassung der produkte von nukleinsäureamplifikation |
| US5945526A (en) | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5800996A (en) | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US5863727A (en) | 1996-05-03 | 1999-01-26 | The Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US6117635A (en) | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US5853992A (en) * | 1996-10-04 | 1998-12-29 | The Regents Of The University Of California | Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels |
| US6365346B1 (en) | 1998-02-18 | 2002-04-02 | Dade Behring Inc. | Quantitative determination of nucleic acid amplification products |
| US6768000B1 (en) | 1998-06-12 | 2004-07-27 | Intergen Company | Multi-fluorescent hairpin energy transfer oligonucleotides |
| US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
| US6610842B1 (en) | 1999-05-06 | 2003-08-26 | Isis Pharmaceuticals, Inc. | Processes for the synthesis of oligomers using phosphoramidite compositions |
| US6524644B1 (en) | 1999-08-26 | 2003-02-25 | Enthone Inc. | Process for selective deposition of OSP coating on copper, excluding deposition on gold |
| US6114518A (en) | 1999-09-30 | 2000-09-05 | Becton, Dickinson And Company | Synthesis and use of labelled phosphoramidite compositions |
| US7019129B1 (en) | 2000-05-09 | 2006-03-28 | Biosearch Technologies, Inc. | Dark quenchers for donor-acceptor energy transfer |
| US6534646B2 (en) | 2001-06-04 | 2003-03-18 | Barrskogen, Inc. | Oligonucleotide labeling reagents |
| US7297494B2 (en) * | 2001-06-25 | 2007-11-20 | Georgia Tech Research Corporation | Activatable probes and methods for in vivo gene detection |
| US20050164316A1 (en) | 2001-06-27 | 2005-07-28 | Bray Terry L. | Biophotonic sensors and methods of use thereof |
| AU2002366046A1 (en) * | 2001-10-19 | 2003-06-10 | Proligo Llc | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes |
| US20040197793A1 (en) | 2002-08-30 | 2004-10-07 | Arjang Hassibi | Methods and apparatus for biomolecule detection, identification, quantification and/or sequencing |
| US20050118619A1 (en) * | 2003-09-22 | 2005-06-02 | Wensheng Xia | Dark quenchers for fluorescence resonance energy transfer (FRET) in bioassays |
| KR101244759B1 (ko) | 2004-06-18 | 2013-03-19 | 엑손모빌 업스트림 리서치 캄파니 | 확장형 용량의 액화 천연 가스 플랜트 |
-
2006
- 2006-10-05 AT AT06806056T patent/ATE519863T1/de active
- 2006-10-05 CN CN200680045298.1A patent/CN101321878B/zh not_active Expired - Fee Related
- 2006-10-05 US US11/544,460 patent/US7741467B2/en not_active Expired - Fee Related
- 2006-10-05 ES ES06806056T patent/ES2371088T3/es active Active
- 2006-10-05 EP EP06806056A patent/EP1934374B1/en not_active Not-in-force
- 2006-10-05 JP JP2008533937A patent/JP4843044B2/ja not_active Expired - Fee Related
- 2006-10-05 WO PCT/EP2006/009646 patent/WO2007039301A2/en not_active Ceased
- 2006-10-05 CA CA2624917A patent/CA2624917C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007039301A3 (en) | 2007-05-24 |
| US7741467B2 (en) | 2010-06-22 |
| CA2624917A1 (en) | 2007-04-12 |
| EP1934374A2 (en) | 2008-06-25 |
| WO2007039301A2 (en) | 2007-04-12 |
| CN101321878B (zh) | 2013-03-27 |
| ES2371088T3 (es) | 2011-12-27 |
| ATE519863T1 (de) | 2011-08-15 |
| CN101321878A (zh) | 2008-12-10 |
| HK1125678A1 (en) | 2009-08-14 |
| JP2009512837A (ja) | 2009-03-26 |
| EP1934374B1 (en) | 2011-08-10 |
| CA2624917C (en) | 2013-07-09 |
| US20070077588A1 (en) | 2007-04-05 |
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