JP4843044B2 - 非蛍光性エネルギー移動 - Google Patents

非蛍光性エネルギー移動 Download PDF

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Publication number
JP4843044B2
JP4843044B2 JP2008533937A JP2008533937A JP4843044B2 JP 4843044 B2 JP4843044 B2 JP 4843044B2 JP 2008533937 A JP2008533937 A JP 2008533937A JP 2008533937 A JP2008533937 A JP 2008533937A JP 4843044 B2 JP4843044 B2 JP 4843044B2
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Japan
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carboxy
moiety
hexachlorofluorescein
acceptor
nucleic acid
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JP2008533937A
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Japanese (ja)
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JP2009512837A5 (enExample
JP2009512837A (ja
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ゴードン ウィル，スティーブン
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Luminescent Compositions (AREA)
JP2008533937A 2005-10-05 2006-10-05 非蛍光性エネルギー移動 Expired - Fee Related JP4843044B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72420205P 2005-10-05 2005-10-05
US60/724,202 2005-10-05
PCT/EP2006/009646 WO2007039301A2 (en) 2005-10-05 2006-10-05 Non-fluorescent energy transfer

Publications (3)

Publication Number Publication Date
JP2009512837A JP2009512837A (ja) 2009-03-26
JP2009512837A5 JP2009512837A5 (enExample) 2009-09-03
JP4843044B2 true JP4843044B2 (ja) 2011-12-21

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JP2008533937A Expired - Fee Related JP4843044B2 (ja) 2005-10-05 2006-10-05 非蛍光性エネルギー移動

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US (1) US7741467B2 (enExample)
EP (1) EP1934374B1 (enExample)
JP (1) JP4843044B2 (enExample)
CN (1) CN101321878B (enExample)
AT (1) ATE519863T1 (enExample)
CA (1) CA2624917C (enExample)
ES (1) ES2371088T3 (enExample)
WO (1) WO2007039301A2 (enExample)

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ES3031673T3 (en) 2018-12-03 2025-07-10 Hoffmann La Roche Compositions and methods for detection of candida auris
JP7628085B2 (ja) 2019-05-02 2025-02-07 エフ． ホフマン－ラ ロシュ アーゲー 鎖分離温度に基づくＤＮＡに対してＲＮＡ標的の優先的／選択的増幅のためのｄＩＴＰの利用
JP7592027B2 (ja) 2019-05-07 2024-11-29 エフ． ホフマン－ラ ロシュ アーゲー ナイセリア・ゴノレア（Ｎｅｉｓｓｅｒｉａ Ｇｏｎｏｒｒｏｈｅａｅ）を検出するための組成物および方法
ES2988562T3 (es) 2019-07-25 2024-11-20 Hoffmann La Roche Composiciones y procedimientos para la detección del virus de Epstein-Barr (VEB)
EP4022086B1 (en) 2019-08-27 2025-08-06 F. Hoffmann-La Roche AG Compositions and methods for amplification and detection of hepatitis b virus rna, including hbv rna transcribed from cccdna
US11441167B2 (en) 2019-11-20 2022-09-13 Roche Molecular Systems, Inc. Compositions and methods for rapid identification and phenotypic antimicrobial susceptibility testing of bacteria and fungi
ES2991814T3 (es) 2019-12-27 2024-12-05 Hoffmann La Roche Composiciones y procedimientos para detectar Staphylococcus aureus resistente a la meticilina
US20220356537A1 (en) 2019-12-31 2022-11-10 Roche Molecular Systems, Inc. Quantitative pcr screening of inducible prophage from bacterial isolates
CA3166337A1 (en) 2020-03-09 2021-09-16 F. Hoffmann-La Roche Ag Compositions and methods for detecting severe acute respiratory syndrome coronavirus 2 (sars-cov-2), influenza a and influenza b
JP2023536962A (ja) 2020-08-06 2023-08-30 エフ． ホフマン－ラ ロシュ アーゲー 重症急性呼吸器症候群コロナウイルス２（ｓａｒｓ－２）、インフルエンザａ及びインフルエンザｂの検出のための組成物及び方法
CN112630198A (zh) * 2020-09-15 2021-04-09 北京工业大学 一种基于回音壁模式光学微腔的传感检测方法
CN116615563A (zh) 2020-12-04 2023-08-18 豪夫迈·罗氏有限公司 用于检测疟疾的组合物和方法
US20220205020A1 (en) 2020-12-30 2022-06-30 Roche Molecular Systems, Inc. Compositions and methods for detection of bacteria and fungi associated with bacterial and candida vaginosis
CN116806268A (zh) 2021-02-05 2023-09-26 豪夫迈·罗氏有限公司 用于检测人副流感病毒1-4(hpiv 1-4)的组合物和方法
US20220290221A1 (en) 2021-03-15 2022-09-15 Roche Molecular Systems, Inc. Compositions and methods for detecting severe acute respiratory syndrome coronavirus 2 (sars-cov-2) variants having spike protein mutations
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US20250003013A1 (en) 2021-11-05 2025-01-02 Roche Molecular Systems, Inc. Compositions and Methods for Detection of Malaria
JP2024539474A (ja) 2021-11-22 2024-10-28 エフ． ホフマン－ラ ロシュ アーゲー 多剤耐性に関連付けられるｖａｎＡ及び／又はｖａｎＢ遺伝子を検出するための組成物及び方法
WO2023118399A1 (en) 2021-12-24 2023-06-29 F. Hoffmann-La Roche Ag Improved detection of lamp amplification products
CN119452104A (zh) 2022-06-30 2025-02-14 豪夫迈·罗氏有限公司 用于检测性病淋巴肉芽肿(lgv)沙眼衣原体血清变型的组合物和方法
EP4577674A1 (en) 2022-08-24 2025-07-02 F. Hoffmann-La Roche AG Compositions and methods for detecting monkeypox virus
CN120418449A (zh) 2022-12-25 2025-08-01 豪夫迈·罗氏有限公司 用于检测耐碳青霉烯的醋酸钙不动杆菌-鲍氏不动杆菌(crab)的组合物和方法
WO2024141476A1 (en) 2022-12-28 2024-07-04 F. Hoffmann-La Roche Ag Digital pcr assay designs for multiple hepatitis b virus gene targets and non-extendable blocker oligonucleotides therefor
CN120731278A (zh) 2023-02-25 2025-09-30 豪夫迈·罗氏有限公司 用于念珠菌属物种检测的组合物和方法
CN120917150A (zh) 2023-03-03 2025-11-07 豪夫迈·罗氏有限公司 用于检测b族链球菌（无乳链球菌）和克林霉素抗性基因决定子的组合物和方法
WO2025027080A1 (en) 2023-08-03 2025-02-06 F. Hoffmann-La Roche Ag Use of 5'-tailed long primers to improve amplification performance when targeting short primer-binding sites
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Also Published As

Publication number Publication date
ATE519863T1 (de) 2011-08-15
HK1125678A1 (en) 2009-08-14
EP1934374A2 (en) 2008-06-25
CA2624917C (en) 2013-07-09
ES2371088T3 (es) 2011-12-27
EP1934374B1 (en) 2011-08-10
US20070077588A1 (en) 2007-04-05
CA2624917A1 (en) 2007-04-12
CN101321878B (zh) 2013-03-27
WO2007039301A2 (en) 2007-04-12
CN101321878A (zh) 2008-12-10
US7741467B2 (en) 2010-06-22
JP2009512837A (ja) 2009-03-26
WO2007039301A3 (en) 2007-05-24

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