CA2624917C - Non-fluorescent energy transfer - Google Patents

Non-fluorescent energy transfer Download PDF

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Publication number
CA2624917C
CA2624917C CA2624917A CA2624917A CA2624917C CA 2624917 C CA2624917 C CA 2624917C CA 2624917 A CA2624917 A CA 2624917A CA 2624917 A CA2624917 A CA 2624917A CA 2624917 C CA2624917 C CA 2624917C
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CA
Canada
Prior art keywords
moiety
nucleic acid
fluorescent
probe
acceptor
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2624917A
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English (en)
French (fr)
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CA2624917A1 (en
Inventor
Stephen Gordon Will
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
CA2624917A 2005-10-05 2006-10-05 Non-fluorescent energy transfer Expired - Fee Related CA2624917C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72420205P 2005-10-05 2005-10-05
US60/724,202 2005-10-05
PCT/EP2006/009646 WO2007039301A2 (en) 2005-10-05 2006-10-05 Non-fluorescent energy transfer

Publications (2)

Publication Number Publication Date
CA2624917A1 CA2624917A1 (en) 2007-04-12
CA2624917C true CA2624917C (en) 2013-07-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2624917A Expired - Fee Related CA2624917C (en) 2005-10-05 2006-10-05 Non-fluorescent energy transfer

Country Status (8)

Country Link
US (1) US7741467B2 (enExample)
EP (1) EP1934374B1 (enExample)
JP (1) JP4843044B2 (enExample)
CN (1) CN101321878B (enExample)
AT (1) ATE519863T1 (enExample)
CA (1) CA2624917C (enExample)
ES (1) ES2371088T3 (enExample)
WO (1) WO2007039301A2 (enExample)

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CN114286866A (zh) 2019-08-27 2022-04-05 豪夫迈·罗氏有限公司 用于扩增和检测包括从cccDNA转录的HBV RNA在内的乙型肝炎病毒RNA的组合物和方法
US11441167B2 (en) 2019-11-20 2022-09-13 Roche Molecular Systems, Inc. Compositions and methods for rapid identification and phenotypic antimicrobial susceptibility testing of bacteria and fungi
JP7716408B2 (ja) 2019-12-27 2025-07-31 エフ. ホフマン-ラ ロシュ アーゲー メチシリン耐性黄色ブドウ球菌を検出するための組成物および方法
US20220356537A1 (en) 2019-12-31 2022-11-10 Roche Molecular Systems, Inc. Quantitative pcr screening of inducible prophage from bacterial isolates
CN116171333A (zh) 2020-03-09 2023-05-26 豪夫迈·罗氏有限公司 用于检测严重急性呼吸综合征冠状病毒2(sars-cov-2)、甲型流感和乙型流感的组合物和方法
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CN112630198A (zh) * 2020-09-15 2021-04-09 北京工业大学 一种基于回音壁模式光学微腔的传感检测方法
CN116615563A (zh) 2020-12-04 2023-08-18 豪夫迈·罗氏有限公司 用于检测疟疾的组合物和方法
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JP2024505686A (ja) 2021-02-05 2024-02-07 エフ. ホフマン-ラ ロシュ アーゲー ヒトパラインフルエンザウイルス1-4(hpiv1-4)の検出のための組成物及び方法
US20220290221A1 (en) 2021-03-15 2022-09-15 Roche Molecular Systems, Inc. Compositions and methods for detecting severe acute respiratory syndrome coronavirus 2 (sars-cov-2) variants having spike protein mutations
US20240240273A1 (en) 2021-05-06 2024-07-18 Roche Molecular Systems, Inc. Compositions and Methods for Detecting Hepatitis Delta Virus by a Dual-Target Assay
CN118202069A (zh) 2021-11-05 2024-06-14 豪夫迈·罗氏有限公司 用于检测疟疾的组合物和方法
WO2023089186A1 (en) 2021-11-22 2023-05-25 F. Hoffmann-La Roche Ag Compositions and methods for detecting vana and/or vanb genes associated with multidrug resistance
CN118434883A (zh) 2021-12-24 2024-08-02 豪夫迈·罗氏有限公司 Lamp扩增产物的改进检测
CN119452104A (zh) 2022-06-30 2025-02-14 豪夫迈·罗氏有限公司 用于检测性病淋巴肉芽肿(lgv)沙眼衣原体血清变型的组合物和方法
WO2024042042A1 (en) 2022-08-24 2024-02-29 F. Hoffmann-La Roche Ag Compositions and methods for detecting monkeypox virus
CN120418449A (zh) 2022-12-25 2025-08-01 豪夫迈·罗氏有限公司 用于检测耐碳青霉烯的醋酸钙不动杆菌-鲍氏不动杆菌(crab)的组合物和方法
CN120457216A (zh) 2022-12-28 2025-08-08 豪夫迈·罗氏有限公司 针对多个乙型肝炎病毒基因靶标的数字pcr测定设计及用于其的不可延伸的阻断剂寡核苷酸
WO2024175749A1 (en) 2023-02-25 2024-08-29 F. Hoffmann-La Roche Ag Compositions and methods for candida species detection
CN120917150A (zh) 2023-03-03 2025-11-07 豪夫迈·罗氏有限公司 用于检测b族链球菌(无乳链球菌)和克林霉素抗性基因决定子的组合物和方法
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Also Published As

Publication number Publication date
EP1934374A2 (en) 2008-06-25
US7741467B2 (en) 2010-06-22
HK1125678A1 (en) 2009-08-14
EP1934374B1 (en) 2011-08-10
US20070077588A1 (en) 2007-04-05
CA2624917A1 (en) 2007-04-12
CN101321878B (zh) 2013-03-27
JP4843044B2 (ja) 2011-12-21
WO2007039301A3 (en) 2007-05-24
CN101321878A (zh) 2008-12-10
JP2009512837A (ja) 2009-03-26
ATE519863T1 (de) 2011-08-15
ES2371088T3 (es) 2011-12-27
WO2007039301A2 (en) 2007-04-12

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