CN101321878B - 非荧光能量转移 - Google Patents

非荧光能量转移 Download PDF

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Publication number
CN101321878B
CN101321878B CN200680045298.1A CN200680045298A CN101321878B CN 101321878 B CN101321878 B CN 101321878B CN 200680045298 A CN200680045298 A CN 200680045298A CN 101321878 B CN101321878 B CN 101321878B
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moiety
nucleic acid
fluorescent
acceptor
probe
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Chinese (zh)
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CN101321878A (zh
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S·G·威尔
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
CN200680045298.1A 2005-10-05 2006-10-05 非荧光能量转移 Expired - Fee Related CN101321878B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72420205P 2005-10-05 2005-10-05
US60/724,202 2005-10-05
PCT/EP2006/009646 WO2007039301A2 (en) 2005-10-05 2006-10-05 Non-fluorescent energy transfer

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CN101321878A CN101321878A (zh) 2008-12-10
CN101321878B true CN101321878B (zh) 2013-03-27

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US (1) US7741467B2 (enExample)
EP (1) EP1934374B1 (enExample)
JP (1) JP4843044B2 (enExample)
CN (1) CN101321878B (enExample)
AT (1) ATE519863T1 (enExample)
CA (1) CA2624917C (enExample)
ES (1) ES2371088T3 (enExample)
WO (1) WO2007039301A2 (enExample)

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CN111786260B (zh) * 2016-06-03 2025-01-24 通用医疗公司 用于微激光器粒子的系统和方法
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US10760137B2 (en) 2017-07-18 2020-09-01 Roche Molecular Systems, Inc. Compositions and methods for detection of Babesia
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US12344905B2 (en) 2018-12-03 2025-07-01 Roche Molecular Systems, Inc. Compositions and methods for detection of Candida auris
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JP7649285B2 (ja) 2019-07-25 2025-03-19 エフ． ホフマン－ラ ロシュ アーゲー エプスタイン・バーウイルス（ｅｂｖ）を検出するための組成物および方法
CN114286866A (zh) 2019-08-27 2022-04-05 豪夫迈·罗氏有限公司 用于扩增和检测包括从cccDNA转录的HBV RNA在内的乙型肝炎病毒RNA的组合物和方法
US11441167B2 (en) 2019-11-20 2022-09-13 Roche Molecular Systems, Inc. Compositions and methods for rapid identification and phenotypic antimicrobial susceptibility testing of bacteria and fungi
JP7716408B2 (ja) 2019-12-27 2025-07-31 エフ． ホフマン－ラ ロシュ アーゲー メチシリン耐性黄色ブドウ球菌を検出するための組成物および方法
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CN116171333A (zh) 2020-03-09 2023-05-26 豪夫迈·罗氏有限公司 用于检测严重急性呼吸综合征冠状病毒2(sars-cov-2)、甲型流感和乙型流感的组合物和方法
AU2021322710A1 (en) 2020-08-06 2023-02-02 F. Hoffmann-La Roche Ag Compositions and methods for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-2), influenza A, and influenza B
CN112630198A (zh) * 2020-09-15 2021-04-09 北京工业大学 一种基于回音壁模式光学微腔的传感检测方法
CN116615563A (zh) 2020-12-04 2023-08-18 豪夫迈·罗氏有限公司 用于检测疟疾的组合物和方法
US20220205020A1 (en) 2020-12-30 2022-06-30 Roche Molecular Systems, Inc. Compositions and methods for detection of bacteria and fungi associated with bacterial and candida vaginosis
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CN118434883A (zh) 2021-12-24 2024-08-02 豪夫迈·罗氏有限公司 Lamp扩增产物的改进检测
CN119452104A (zh) 2022-06-30 2025-02-14 豪夫迈·罗氏有限公司 用于检测性病淋巴肉芽肿(lgv)沙眼衣原体血清变型的组合物和方法
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CN120418449A (zh) 2022-12-25 2025-08-01 豪夫迈·罗氏有限公司 用于检测耐碳青霉烯的醋酸钙不动杆菌-鲍氏不动杆菌(crab)的组合物和方法
CN120457216A (zh) 2022-12-28 2025-08-08 豪夫迈·罗氏有限公司 针对多个乙型肝炎病毒基因靶标的数字pcr测定设计及用于其的不可延伸的阻断剂寡核苷酸
WO2024175749A1 (en) 2023-02-25 2024-08-29 F. Hoffmann-La Roche Ag Compositions and methods for candida species detection
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Publication number Publication date
EP1934374A2 (en) 2008-06-25
US7741467B2 (en) 2010-06-22
HK1125678A1 (en) 2009-08-14
EP1934374B1 (en) 2011-08-10
US20070077588A1 (en) 2007-04-05
CA2624917A1 (en) 2007-04-12
JP4843044B2 (ja) 2011-12-21
WO2007039301A3 (en) 2007-05-24
CN101321878A (zh) 2008-12-10
CA2624917C (en) 2013-07-09
JP2009512837A (ja) 2009-03-26
ATE519863T1 (de) 2011-08-15
ES2371088T3 (es) 2011-12-27
WO2007039301A2 (en) 2007-04-12

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