JP4796259B2 - 複数のアナライトの検出において使用するための組成物 - Google Patents

複数のアナライトの検出において使用するための組成物 Download PDF

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JP4796259B2
JP4796259B2 JP2001581129A JP2001581129A JP4796259B2 JP 4796259 B2 JP4796259 B2 JP 4796259B2 JP 2001581129 A JP2001581129 A JP 2001581129A JP 2001581129 A JP2001581129 A JP 2001581129A JP 4796259 B2 JP4796259 B2 JP 4796259B2
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sensitizer
reagent
different
reactive
singlet oxygen
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JP2003532119A (ja
JP2003532119A5 (https=
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ジョン・エス・ピーズ
レミー・クローマー
ラージェシュ・パテール
ヌーリス・クーン
スティーヴ・デケツァー
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シーメンス・ヘルスケア・ダイアグノスティックス・プロダクツ・ゲーエムベーハー
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/025—Silicon compounds without C-silicon linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2001581129A 2000-05-04 2001-05-03 複数のアナライトの検出において使用するための組成物 Expired - Lifetime JP4796259B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56423000A 2000-05-04 2000-05-04
US09/564,230 2000-05-04
PCT/US2001/014528 WO2001084157A2 (en) 2000-05-04 2001-05-03 Compositions for detection of multiple analytes

Publications (3)

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JP2003532119A JP2003532119A (ja) 2003-10-28
JP2003532119A5 JP2003532119A5 (https=) 2008-04-24
JP4796259B2 true JP4796259B2 (ja) 2011-10-19

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JP2001581129A Expired - Lifetime JP4796259B2 (ja) 2000-05-04 2001-05-03 複数のアナライトの検出において使用するための組成物

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US (2) US20110124001A1 (https=)
EP (2) EP2341349A1 (https=)
JP (1) JP4796259B2 (https=)
ES (1) ES2370232T3 (https=)
WO (1) WO2001084157A2 (https=)

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RU2007114042A (ru) * 2004-09-17 2008-10-27 Чирон Корпорейшн (Us) Гомогенный люминесцентный способ анализа при сближении, опосредованного трехвалентным металлом
US7939267B2 (en) 2004-11-04 2011-05-10 Laboratory Corporation Of America Holdings Detection of activation of endothelial cells as surrogate marker for angiogenesis
CA2669398C (en) 2006-11-13 2016-01-05 Perkinelmer Las, Inc. Detecting molecular interactions comprising a target-selective binding agent and a target molecule with fluorescence resonance energy transfer (fret)
JP2010523751A (ja) * 2007-04-05 2010-07-15 ビーエーエスエフ ソシエタス・ヨーロピア シリコンおよびゲルマニウムフタロシアニンならびに関連物質の製造
CA2711843C (en) 2007-12-20 2018-11-13 Laboratory Corporation Of America Holdings Her-2 diagnostic methods
US8084215B2 (en) 2008-04-29 2011-12-27 Psychemedics Corporation Non-proteolytic method for the determination of analytes in keratinized structures
CN102077094B (zh) 2008-04-29 2016-03-09 赛凯米迪克斯股份有限公司 固相多分析物测试
US8470542B2 (en) 2008-12-01 2013-06-25 Laboratory Corporation Of America Holdings Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95
US20120295259A1 (en) 2011-05-19 2012-11-22 Laboratory Corporation Of America Holdings Methods for Determining the Likelihood of Survival and for Predicting Likelihood of Metastasis in Cancer Patients
SG172983A1 (en) 2009-01-15 2011-08-29 Lab Corp America Holdings Methods of determining patient response by measurement of her-3
EP2398868B1 (en) 2009-02-20 2016-06-15 Perkinelmer Biosignal, Inc. Multiplex assay methods and compositions
WO2014005065A1 (en) 2012-06-28 2014-01-03 Psychemedics Corporation Detection of analytes in hair wash samples
WO2014165855A1 (en) 2013-04-05 2014-10-09 Laboratory Corporation Of America Holdings Systems and methods for facilitating diagnosis, prognosis and treatment of cancer based on detection of her3 activation
AU2019217331B2 (en) * 2018-01-30 2024-11-07 Sri International Computational generation of chemical synthesis routes and methods
CN113376146A (zh) * 2020-02-25 2021-09-10 上海交通大学 适于生物分子多重检测的检测颗粒及其制备方法与应用
CN112326618B (zh) * 2020-11-06 2022-11-01 安徽师范大学 一种对苯二酚的检测方法
CN112964654A (zh) * 2021-01-28 2021-06-15 上海中西三维药业有限公司 一种含氯废水中氨氮含量的测定方法及其应用
CN120137650B (zh) * 2025-03-14 2026-04-14 上海交通大学 单重态裂分敏化型光化学长余辉体系与应用

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JPH05180773A (ja) * 1991-05-22 1993-07-23 Syntex Usa Inc ルミネセンスを利用する分析方法
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US5397819A (en) * 1991-11-08 1995-03-14 Eastman Chemical Company Thermoplastic materials containing near infrared fluorophores
JPH0783927A (ja) * 1993-09-13 1995-03-31 Toshiba Corp 超微粒子無機蛍光体標識特異的結合物質およびこれを用いた検出方法
US5525516A (en) * 1994-09-30 1996-06-11 Eastman Chemical Company Method for tagging petroleum products
WO1997023647A1 (en) * 1995-12-22 1997-07-03 Behringwerke Aktiengesellschaft Homogeneous amplification and detection of nucleic acids
JPH1151935A (ja) * 1997-08-06 1999-02-26 Aisin Seiki Co Ltd 複数種類のターゲット分子の同時検出方法
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JP2003507025A (ja) * 1999-08-17 2003-02-25 デイド・ベーリング・インコーポレイテッド 偶発的ｄｎａ分枝移動の抑制による核酸の相違の検出

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JPH03279860A (ja) * 1990-03-29 1991-12-11 Mitsui Petrochem Ind Ltd 検査方法及び検査試薬
JPH05180773A (ja) * 1991-05-22 1993-07-23 Syntex Usa Inc ルミネセンスを利用する分析方法
US5397819A (en) * 1991-11-08 1995-03-14 Eastman Chemical Company Thermoplastic materials containing near infrared fluorophores
JPH06157536A (ja) * 1992-11-26 1994-06-03 Toyo Ink Mfg Co Ltd シリコンフタロシアニン化合物およびシリコンナフタロシアニン化合物の製造法
JPH0783927A (ja) * 1993-09-13 1995-03-31 Toshiba Corp 超微粒子無機蛍光体標識特異的結合物質およびこれを用いた検出方法
US5525516A (en) * 1994-09-30 1996-06-11 Eastman Chemical Company Method for tagging petroleum products
US5525516B1 (en) * 1994-09-30 1999-11-09 Eastman Chem Co Method for tagging petroleum products
WO1997023647A1 (en) * 1995-12-22 1997-07-03 Behringwerke Aktiengesellschaft Homogeneous amplification and detection of nucleic acids
JPH1151935A (ja) * 1997-08-06 1999-02-26 Aisin Seiki Co Ltd 複数種類のターゲット分子の同時検出方法
WO1999042618A1 (en) * 1998-02-18 1999-08-26 Dade Behring Inc. Quantitative determination of nucleic acid amplification products
JP2003507025A (ja) * 1999-08-17 2003-02-25 デイド・ベーリング・インコーポレイテッド 偶発的ｄｎａ分枝移動の抑制による核酸の相違の検出

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Publication number Publication date
EP2341349A1 (en) 2011-07-06
JP2003532119A (ja) 2003-10-28
EP1305632A2 (en) 2003-05-02
US20130210003A1 (en) 2013-08-15
WO2001084157A3 (en) 2003-02-06
ES2370232T3 (es) 2011-12-13
EP1305632B1 (en) 2011-07-27
WO2001084157A2 (en) 2001-11-08
US20110124001A1 (en) 2011-05-26

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