JP4733272B2 - ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子 - Google Patents

ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子 Download PDF

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Publication number
JP4733272B2
JP4733272B2 JP2000592310A JP2000592310A JP4733272B2 JP 4733272 B2 JP4733272 B2 JP 4733272B2 JP 2000592310 A JP2000592310 A JP 2000592310A JP 2000592310 A JP2000592310 A JP 2000592310A JP 4733272 B2 JP4733272 B2 JP 4733272B2
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Japan
Prior art keywords
cys
pro
ala
factor viii
gly
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JP2000592310A
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English (en)
Japanese (ja)
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JP2002536297A (ja
Inventor
ユ，ジナン
ポッター，エム．，ダニエル
ケリー，ブライアン，ディー．
ディーツ，ジェフェリー，エス．
ブース，ジェームズ，イー．
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Dyax Corp
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Dyax Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Reciprocating Pumps (AREA)
JP2000592310A 1999-01-04 2000-01-03 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子 Expired - Lifetime JP4733272B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/224,785 1999-01-04
US09/224,785 US6197526B1 (en) 1999-01-04 1999-01-04 Polypeptides for binding human factor VIII and fragments of human factor VIII
PCT/US2000/000043 WO2000040602A1 (en) 1999-01-04 2000-01-03 Binding molecules for human factor viii and factor viii-like proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010108017A Division JP5368371B2 (ja) 1999-01-04 2010-05-10 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子

Publications (2)

Publication Number Publication Date
JP2002536297A JP2002536297A (ja) 2002-10-29
JP4733272B2 true JP4733272B2 (ja) 2011-07-27

Family

ID=22842198

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000592310A Expired - Lifetime JP4733272B2 (ja) 1999-01-04 2000-01-03 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子
JP2010108017A Expired - Lifetime JP5368371B2 (ja) 1999-01-04 2010-05-10 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子
JP2012284538A Expired - Lifetime JP5572207B2 (ja) 1999-01-04 2012-12-27 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010108017A Expired - Lifetime JP5368371B2 (ja) 1999-01-04 2010-05-10 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子
JP2012284538A Expired - Lifetime JP5572207B2 (ja) 1999-01-04 2012-12-27 ヒト第ｖｉｉｉ因子および第ｖｉｉｉ因子様タンパク質に対する結合分子

Country Status (12)

Country Link
US (2) US6197526B1 (enExample)
EP (5) EP1705183B1 (enExample)
JP (3) JP4733272B2 (enExample)
AT (1) ATE433992T1 (enExample)
AU (3) AU769745B2 (enExample)
CA (1) CA2354599C (enExample)
DE (1) DE60042430D1 (enExample)
DK (4) DK2298791T3 (enExample)
ES (4) ES2390360T3 (enExample)
HK (1) HK1038756A1 (enExample)
PT (3) PT2301953E (enExample)
WO (1) WO2000040602A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820796B2 (en) * 1998-03-12 2010-10-26 Genetics Institute, Llc. Methods for producing Factor VIII proteins
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) * 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
WO2003093821A1 (en) * 2002-04-29 2003-11-13 Affibody Ab Sandwich assay and kit
EP1968999A2 (en) * 2005-12-07 2008-09-17 Technische Universität München Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
AU2008236694B2 (en) 2007-04-04 2014-01-23 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
CA2694824A1 (en) 2007-08-09 2009-02-12 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
TWI573806B (zh) 2008-04-17 2017-03-11 巴克斯歐塔公司 生物活性胜肽
WO2010014909A1 (en) * 2008-08-01 2010-02-04 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
DK2717898T3 (en) * 2011-06-10 2019-03-25 Bioverativ Therapeutics Inc COAGULATING COMPOUNDS AND PROCEDURES FOR USE THEREOF
JP6702866B2 (ja) 2013-11-18 2020-06-03 ルビウス セラピューティクス， インコーポレイテッド 合成膜−レシーバー複合体
EP3515932B1 (en) 2016-09-19 2023-11-22 F. Hoffmann-La Roche AG Complement factor based affinity chromatography
US11123704B2 (en) 2017-08-04 2021-09-21 Takeda Pharmaceutical Company Limited Antibody-resin coupling apparatus and methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
JPH0788399B2 (ja) 1985-04-12 1995-09-27 ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド 新規プロコアギュラント蛋白質
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP1997891A1 (en) * 1988-09-02 2008-12-03 Dyax Corporation Generation and selection of recombinant varied binding proteins
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
SE468050C (sv) * 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
EP0648268A1 (en) * 1991-03-27 1995-04-19 The Scripps Research Institute Therapeutic fragments of von willebrand factor
ES2229347T3 (es) * 1996-03-20 2005-04-16 Dyax Corp. Purificacion del activador del plasminogeno tisular tpa.
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
JP2000512981A (ja) 1996-06-06 2000-10-03 ラ ホヤ ファーマシューティカル カンパニー ａＰＬ免疫応答性ペプチド、その結合体およびａＰＬ抗体媒介病理のための処置方法
PT1095143E (pt) * 1998-05-08 2008-11-28 Sanquin Bloedvoorziening Inibidor para o diagnóstico e tratamento de doentes com hemofilia a
US5994310A (en) 1998-09-03 1999-11-30 Bayer Corporation Peptide ligands for affinity purification of human Factor VIII
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII

Also Published As

Publication number Publication date
EP1147128A4 (en) 2004-10-13
EP1705183A1 (en) 2006-09-27
EP2090582A2 (en) 2009-08-19
DK1705183T3 (da) 2009-10-19
EP2298791A1 (en) 2011-03-23
US20010014456A1 (en) 2001-08-16
HK1038756A1 (zh) 2002-03-28
ES2328722T3 (es) 2009-11-17
AU2004201810A1 (en) 2004-05-27
DK2090582T3 (da) 2012-10-15
JP2010254694A (ja) 2010-11-11
EP2298791B8 (en) 2014-12-24
EP2090582B1 (en) 2012-09-19
PT2301953E (pt) 2014-09-15
JP2002536297A (ja) 2002-10-29
JP5368371B2 (ja) 2013-12-18
ES2390360T3 (es) 2012-11-12
EP2301953A1 (en) 2011-03-30
CA2354599C (en) 2013-03-12
HK1155182A1 (en) 2012-05-11
JP2013079272A (ja) 2013-05-02
CA2354599A1 (en) 2000-07-13
EP1705183B1 (en) 2009-06-17
AU2004201830A1 (en) 2004-05-27
AU2598200A (en) 2000-07-24
ES2524965T3 (es) 2014-12-16
WO2000040602A1 (en) 2000-07-13
JP5572207B2 (ja) 2014-08-13
US6197526B1 (en) 2001-03-06
HK1131398A1 (en) 2010-01-22
EP1147128A1 (en) 2001-10-24
AU769745B2 (en) 2004-02-05
ATE433992T1 (de) 2009-07-15
US6492105B2 (en) 2002-12-10
EP2090582A3 (en) 2009-11-11
EP2301953B1 (en) 2014-07-30
AU2004201830B2 (en) 2007-04-05
EP2298791B1 (en) 2014-11-12
ES2499040T3 (es) 2014-09-26
PT2298791E (pt) 2014-12-16
DK2298791T3 (en) 2014-12-08
PT1705183E (pt) 2009-07-31
HK1155756A1 (en) 2012-05-25
DK2301953T3 (da) 2014-09-22
DE60042430D1 (de) 2009-07-30

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