ATE433992T1 - An menschlichen faktor-viii bindende moleküle und faktor-viii-ähnliche proteine - Google Patents

An menschlichen faktor-viii bindende moleküle und faktor-viii-ähnliche proteine

Info

Publication number
ATE433992T1
ATE433992T1 AT06009040T AT06009040T ATE433992T1 AT E433992 T1 ATE433992 T1 AT E433992T1 AT 06009040 T AT06009040 T AT 06009040T AT 06009040 T AT06009040 T AT 06009040T AT E433992 T1 ATE433992 T1 AT E433992T1
Authority
AT
Austria
Prior art keywords
factor viii
proteins
binding molecules
human factor
human
Prior art date
Application number
AT06009040T
Other languages
English (en)
Inventor
Jinan Yu
Daniel M Potter
Brian D Kelley
Jeffrey S Deetz
James E Booth
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Application granted granted Critical
Publication of ATE433992T1 publication Critical patent/ATE433992T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Reciprocating Pumps (AREA)
AT06009040T 1999-01-04 2000-01-03 An menschlichen faktor-viii bindende moleküle und faktor-viii-ähnliche proteine ATE433992T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/224,785 US6197526B1 (en) 1999-01-04 1999-01-04 Polypeptides for binding human factor VIII and fragments of human factor VIII

Publications (1)

Publication Number Publication Date
ATE433992T1 true ATE433992T1 (de) 2009-07-15

Family

ID=22842198

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06009040T ATE433992T1 (de) 1999-01-04 2000-01-03 An menschlichen faktor-viii bindende moleküle und faktor-viii-ähnliche proteine

Country Status (12)

Country Link
US (2) US6197526B1 (de)
EP (5) EP2298791B8 (de)
JP (3) JP4733272B2 (de)
AT (1) ATE433992T1 (de)
AU (3) AU769745B2 (de)
CA (1) CA2354599C (de)
DE (1) DE60042430D1 (de)
DK (4) DK2298791T3 (de)
ES (4) ES2328722T3 (de)
HK (1) HK1038756A1 (de)
PT (3) PT2301953E (de)
WO (1) WO2000040602A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820796B2 (en) * 1998-03-12 2010-10-26 Genetics Institute, Llc. Methods for producing Factor VIII proteins
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
CA2483408A1 (en) * 2002-04-29 2003-11-13 Affibody Ab Sandwich assay and kit
US20090215025A1 (en) * 2005-12-07 2009-08-27 Technische Universitat Munchen Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
TW200745163A (en) * 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
CN101680873B (zh) 2007-04-04 2015-11-25 加利福尼亚大学董事会 使用纳米孔的组合物、设备、系统和方法
MX2010001363A (es) 2007-08-09 2010-03-09 Syntonix Pharmaceuticals Inc Peptidos inmunomoduladores.
TWI573806B (zh) 2008-04-17 2017-03-11 巴克斯歐塔公司 生物活性胜肽
US20100048488A1 (en) * 2008-08-01 2010-02-25 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
AU2011343813B2 (en) 2010-12-15 2015-05-21 Takeda Pharmaceutical Company Limited Eluate collection using conductivity gradient
WO2012170969A2 (en) * 2011-06-10 2012-12-13 Biogen Idec Ma Inc. Pro-coagulant compounds and methods of use thereof
WO2015073587A2 (en) 2013-11-18 2015-05-21 Rubius Therapeutics, Inc. Synthetic membrane-receiver complexes
CN116731197A (zh) * 2016-09-19 2023-09-12 豪夫迈·罗氏有限公司 基于补体因子的亲和层析
KR20230143193A (ko) 2017-08-04 2023-10-11 다케다 야쿠힌 고교 가부시키가이샤 항체-수지 커플링 장치 및 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
WO1986006101A1 (en) 1985-04-12 1986-10-23 Genetics Institute, Inc. Novel procoagulant proteins
EP1892296A1 (de) * 1988-09-02 2008-02-27 Dyax Corporation Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
SE468050C (sv) * 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
EP0648268A1 (de) * 1991-03-27 1995-04-19 The Scripps Research Institute Therapeutische fragmente des von willebrand faktors
EP0907887A4 (de) * 1996-03-20 2002-10-30 Dyax Corp Durch genmanipulation erhaltene affinitätsliganden für makromoleküle
KR20000016414A (ko) 1996-06-06 2000-03-25 와이즈먼 앤드루 Apl 면역반응성 펩티드, 그것의 콘주게이트 및 apl항체-매개병변의 치료방법
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
ATE405649T1 (de) * 1998-05-08 2008-09-15 Sanquin Bloedvoorziening Hemmstoff zur diagnose und behandlung von haemophilia a patienten
US5994310A (en) 1998-09-03 1999-11-30 Bayer Corporation Peptide ligands for affinity purification of human Factor VIII
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII

Also Published As

Publication number Publication date
HK1038756A1 (zh) 2002-03-28
EP2301953B1 (de) 2014-07-30
WO2000040602A1 (en) 2000-07-13
PT2301953E (pt) 2014-09-15
US20010014456A1 (en) 2001-08-16
AU2004201830A1 (en) 2004-05-27
JP5368371B2 (ja) 2013-12-18
ES2390360T3 (es) 2012-11-12
US6492105B2 (en) 2002-12-10
HK1131398A1 (en) 2010-01-22
JP4733272B2 (ja) 2011-07-27
EP1705183A1 (de) 2006-09-27
EP2298791B8 (de) 2014-12-24
AU769745B2 (en) 2004-02-05
ES2328722T3 (es) 2009-11-17
EP2090582A3 (de) 2009-11-11
HK1155182A1 (en) 2012-05-11
DK2301953T3 (da) 2014-09-22
JP2002536297A (ja) 2002-10-29
DK2090582T3 (da) 2012-10-15
EP2090582A2 (de) 2009-08-19
PT2298791E (pt) 2014-12-16
EP2298791B1 (de) 2014-11-12
AU2004201830B2 (en) 2007-04-05
EP2298791A1 (de) 2011-03-23
AU2598200A (en) 2000-07-24
CA2354599A1 (en) 2000-07-13
ES2524965T3 (es) 2014-12-16
EP2090582B1 (de) 2012-09-19
HK1155756A1 (en) 2012-05-25
ES2499040T3 (es) 2014-09-26
DK2298791T3 (en) 2014-12-08
DK1705183T3 (da) 2009-10-19
PT1705183E (pt) 2009-07-31
JP2010254694A (ja) 2010-11-11
AU2004201810A1 (en) 2004-05-27
EP1147128A4 (de) 2004-10-13
EP1147128A1 (de) 2001-10-24
EP1705183B1 (de) 2009-06-17
JP5572207B2 (ja) 2014-08-13
DE60042430D1 (de) 2009-07-30
US6197526B1 (en) 2001-03-06
EP2301953A1 (de) 2011-03-30
CA2354599C (en) 2013-03-12
JP2013079272A (ja) 2013-05-02

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