PT2298791E - Moléculas de ligação para fator viii humano e proteinas de tipo fator viii - Google Patents

Moléculas de ligação para fator viii humano e proteinas de tipo fator viii Download PDF

Info

Publication number
PT2298791E
PT2298791E PT101827418T PT10182741T PT2298791E PT 2298791 E PT2298791 E PT 2298791E PT 101827418 T PT101827418 T PT 101827418T PT 10182741 T PT10182741 T PT 10182741T PT 2298791 E PT2298791 E PT 2298791E
Authority
PT
Portugal
Prior art keywords
factor viii
proteins
binding molecules
human factor
human
Prior art date
Application number
PT101827418T
Other languages
English (en)
Inventor
Brian D Kelley
Jinan Yu
Daniel M Potter
Jeffrey S Deetz
James E Booth
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Publication of PT2298791E publication Critical patent/PT2298791E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Reciprocating Pumps (AREA)
PT101827418T 1999-01-04 2000-01-03 Moléculas de ligação para fator viii humano e proteinas de tipo fator viii PT2298791E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/224,785 US6197526B1 (en) 1999-01-04 1999-01-04 Polypeptides for binding human factor VIII and fragments of human factor VIII

Publications (1)

Publication Number Publication Date
PT2298791E true PT2298791E (pt) 2014-12-16

Family

ID=22842198

Family Applications (3)

Application Number Title Priority Date Filing Date
PT06009040T PT1705183E (pt) 1999-01-04 2000-01-03 Moléculas de ligação para o factor viii humano e proteínas de tipo factor viii
PT101827475T PT2301953E (pt) 1999-01-04 2000-01-03 Moléculas de ligação ao factor viii humano e a proteínas semelhantes ao factor viii
PT101827418T PT2298791E (pt) 1999-01-04 2000-01-03 Moléculas de ligação para fator viii humano e proteinas de tipo fator viii

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PT06009040T PT1705183E (pt) 1999-01-04 2000-01-03 Moléculas de ligação para o factor viii humano e proteínas de tipo factor viii
PT101827475T PT2301953E (pt) 1999-01-04 2000-01-03 Moléculas de ligação ao factor viii humano e a proteínas semelhantes ao factor viii

Country Status (12)

Country Link
US (2) US6197526B1 (pt)
EP (5) EP2301953B1 (pt)
JP (3) JP4733272B2 (pt)
AT (1) ATE433992T1 (pt)
AU (3) AU769745B2 (pt)
CA (1) CA2354599C (pt)
DE (1) DE60042430D1 (pt)
DK (4) DK2301953T3 (pt)
ES (4) ES2524965T3 (pt)
HK (4) HK1038756A1 (pt)
PT (3) PT1705183E (pt)
WO (1) WO2000040602A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820796B2 (en) * 1998-03-12 2010-10-26 Genetics Institute, Llc. Methods for producing Factor VIII proteins
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FR2830865B1 (fr) 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
JP4554356B2 (ja) * 2002-04-29 2010-09-29 アフィボディ・アーベー サンドイッチアッセイおよびキット
CA2632714A1 (en) * 2005-12-07 2007-06-14 Technische Universitaet Muenchen Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
CA2684801C (en) 2007-04-04 2017-10-10 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
EA201070231A1 (ru) 2007-08-09 2010-10-29 Синтоникс Фармасьютикалз, Инк. Иммуномодулирующие пептиды
TWI541020B (zh) 2008-04-17 2016-07-11 巴克斯歐塔公司 生物活性胜肽
US20100048488A1 (en) * 2008-08-01 2010-02-25 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
SI2717898T1 (sl) * 2011-06-10 2019-07-31 Bioverativ Therapeutics Inc. Spojine prokoagulantov in metode za njihovo uporabo
CA2930665A1 (en) 2013-11-18 2015-05-21 Rubius Therapeutics, Inc. Synthetic membrane-receiver complexes
EP3515932B1 (en) 2016-09-19 2023-11-22 F. Hoffmann-La Roche AG Complement factor based affinity chromatography
EP3661636B1 (en) 2017-08-04 2023-11-15 Takeda Pharmaceutical Company Limited Antibody-resin coupling apparatus and methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
US4868112A (en) 1985-04-12 1989-09-19 Genetics Institute, Inc. Novel procoagulant proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP1892296A1 (en) * 1988-09-02 2008-02-27 Dyax Corporation Generation and selection of recombinant varied binding proteins
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
SE468050C (sv) * 1991-03-15 1998-02-11 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
CA2107100A1 (en) * 1991-03-27 1992-09-28 Zaverio M. Ruggeri Therapeutic fragments of von willebrand factor
PT904541E (pt) * 1996-03-20 2005-01-31 Dyax Corp Purificacao de activador de plasminogenio tecidual (tpa)
CA2256449A1 (en) 1996-06-06 1997-12-11 Lajolla Pharmaceutical Company Apl immunoreactive peptides, conjugates thereof and methods of treatment for apl antibody-mediated pathologies
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
WO1999058680A2 (en) * 1998-05-08 1999-11-18 Stichting Sanquin Bloedvoorziening Method for diagnosis and treatment of haemophilia a patients with an inhibitor
US5994310A (en) 1998-09-03 1999-11-30 Bayer Corporation Peptide ligands for affinity purification of human Factor VIII
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII

Also Published As

Publication number Publication date
EP2301953A1 (en) 2011-03-30
EP2298791B1 (en) 2014-11-12
EP1147128A1 (en) 2001-10-24
JP2010254694A (ja) 2010-11-11
EP2090582B1 (en) 2012-09-19
JP2002536297A (ja) 2002-10-29
DE60042430D1 (de) 2009-07-30
EP2298791B8 (en) 2014-12-24
EP2298791A1 (en) 2011-03-23
ATE433992T1 (de) 2009-07-15
JP5572207B2 (ja) 2014-08-13
AU769745B2 (en) 2004-02-05
ES2524965T3 (es) 2014-12-16
US20010014456A1 (en) 2001-08-16
DK2298791T3 (en) 2014-12-08
DK2090582T3 (da) 2012-10-15
EP2090582A3 (en) 2009-11-11
JP4733272B2 (ja) 2011-07-27
HK1131398A1 (en) 2010-01-22
AU2004201830B2 (en) 2007-04-05
DK1705183T3 (da) 2009-10-19
HK1155756A1 (en) 2012-05-25
CA2354599A1 (en) 2000-07-13
PT2301953E (pt) 2014-09-15
AU2004201830A1 (en) 2004-05-27
PT1705183E (pt) 2009-07-31
EP1705183A1 (en) 2006-09-27
JP5368371B2 (ja) 2013-12-18
EP1705183B1 (en) 2009-06-17
US6492105B2 (en) 2002-12-10
AU2598200A (en) 2000-07-24
EP1147128A4 (en) 2004-10-13
EP2090582A2 (en) 2009-08-19
ES2328722T3 (es) 2009-11-17
HK1038756A1 (zh) 2002-03-28
DK2301953T3 (da) 2014-09-22
WO2000040602A1 (en) 2000-07-13
EP2301953B1 (en) 2014-07-30
CA2354599C (en) 2013-03-12
US6197526B1 (en) 2001-03-06
ES2390360T3 (es) 2012-11-12
ES2499040T3 (es) 2014-09-26
HK1155182A1 (en) 2012-05-11
AU2004201810A1 (en) 2004-05-27
JP2013079272A (ja) 2013-05-02

Similar Documents

Publication Publication Date Title
HK1131398A1 (en) Binding molecules for human factor viii and factor viii-like proteins
EP2267018A3 (en) Binding polypeptides for B lymphocyte stimulator protein (BLyS)
WO2001004265A3 (en) C-terminal protein tagging
AU3186397A (en) Prion protein binding proteins and uses thereof
EP1243923A4 (en) METHOD FOR SELECTING A CANCER REMEDY USING P53 AND MORTALIN INTERACTION AREAS
ZA975588B (en) Isolated nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof.
IL147527A0 (en) Conjugates and methods for the production thereof, and their use for transporting molecules via biological membranes
ZA9710163B (en) Novel carboxylesterase nucleic acid molecules, proteins and uses thereof.
WO2000068424A3 (en) Means for detecting and treating pathologies linked to fgfr3
AU3746000A (en) Polynucleotide encoding autoantigens associated with endometriosis
AU1174402A (en) Nucleic acid molecules and polypeptides for immune modulation
EP1016717A4 (en) NEW PROTEIN EXPRESSES IN LIVER CANCER, GENE-ENCODING IT, ANTIBODIES AGAINST IT AND A METHOD FOR DETECTING THE EXPRESSION OF THIS PROTEIN
WO2000057188A3 (fr) Proteines associees a un cancer mammaire et procede de detection de ces proteines
EP1186662A3 (en) Prion binding proteins and uses thereof
WO2001021794A3 (en) Smad associating polypeptides
WO2001034803A3 (en) Crib protein zmse1
AU2001293665A1 (en) Method for quantitatively determining the available binding capacity in an aqueous protein solution