WO2001034803A3 - Crib protein zmse1 - Google Patents

Crib protein zmse1 Download PDF

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Publication number
WO2001034803A3
WO2001034803A3 PCT/US2000/030945 US0030945W WO0134803A3 WO 2001034803 A3 WO2001034803 A3 WO 2001034803A3 US 0030945 W US0030945 W US 0030945W WO 0134803 A3 WO0134803 A3 WO 0134803A3
Authority
WO
WIPO (PCT)
Prior art keywords
zmse1
crib
protein
polypeptides
present
Prior art date
Application number
PCT/US2000/030945
Other languages
French (fr)
Other versions
WO2001034803A2 (en
Inventor
James L Holloway
Zeren Gao
Theodore E Whitmore
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to CA002390491A priority Critical patent/CA2390491A1/en
Priority to EP00980335A priority patent/EP1228211A2/en
Priority to AU17611/01A priority patent/AU1761101A/en
Publication of WO2001034803A2 publication Critical patent/WO2001034803A2/en
Publication of WO2001034803A3 publication Critical patent/WO2001034803A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to polynucleotide and polypeptide molecules for zmse1, a novel human CRIB protein. The polypeptides, and polynucleotides encoding them, may be used for detecting human chromosomal abnormalities and cancers. The present invention also includes antibodies to the zmse1 polypeptides.
PCT/US2000/030945 1999-11-10 2000-11-09 Crib protein zmse1 WO2001034803A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002390491A CA2390491A1 (en) 1999-11-10 2000-11-09 Crib protein zmse1
EP00980335A EP1228211A2 (en) 1999-11-10 2000-11-09 Crib protein zmse1
AU17611/01A AU1761101A (en) 1999-11-10 2000-11-09 Novel crib protein zmse1

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43856499A 1999-11-10 1999-11-10
US09/438,564 1999-11-10

Publications (2)

Publication Number Publication Date
WO2001034803A2 WO2001034803A2 (en) 2001-05-17
WO2001034803A3 true WO2001034803A3 (en) 2002-01-17

Family

ID=23741118

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/030945 WO2001034803A2 (en) 1999-11-10 2000-11-09 Crib protein zmse1

Country Status (4)

Country Link
EP (1) EP1228211A2 (en)
AU (1) AU1761101A (en)
CA (1) CA2390491A1 (en)
WO (1) WO2001034803A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999051727A2 (en) * 1998-04-03 1999-10-14 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences of normal ovary tissue

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999051727A2 (en) * 1998-04-03 1999-10-14 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences of normal ovary tissue

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BAHOU ET AL: "cDNA cloning and molecular characterization of MSE55, a novel human serum constituent protein that displays bone marrow stromal/endothelial cell-specific expression", JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 267, no. 20, 15 July 1992 (1992-07-15), pages 13986 - 13992, XP002128573, ISSN: 0021-9258 *
BURBELO PETER D ET AL: "A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 49, 1995, pages 29071 - 29074, XP002137877, ISSN: 0021-9258 *
BURBELO PETER D ET AL: "MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 96, no. 16, 3 August 1999 (1999-08-03), Aug. 3, 1999, pages 9083 - 9088, XP002168526, ISSN: 0027-8424 *
DATABASE EMBL 11 March 1999 (1999-03-11), HIRSCH D.S. ET AL.: "Homo sapiens Cdc42 effector protein 4 mRNA", XP002168527 *
HIRSCH DIANNE SNOW ET AL: "A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 2, 12 January 2001 (2001-01-12), pages 875 - 883, XP002168524, ISSN: 0021-9258 *
JOBERTY GERARD ET AL: "The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.", MOLECULAR AND CELLULAR BIOLOGY, vol. 19, no. 10, October 1999 (1999-10-01), pages 6585 - 6597, XP002168525, ISSN: 0270-7306 *
OSADA NAOKI ET AL: "Sequence analysis, gene expression, and chromosomal assignment of mouse Borg4 gene and its human orthologue.", JOURNAL OF HUMAN GENETICS, vol. 45, no. 6, November 2000 (2000-11-01), pages 374 - 377, XP001002527, ISSN: 1434-5161 *

Also Published As

Publication number Publication date
AU1761101A (en) 2001-06-06
EP1228211A2 (en) 2002-08-07
WO2001034803A2 (en) 2001-05-17
CA2390491A1 (en) 2001-05-17

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