DK2090582T3 - Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner - Google Patents

Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner

Info

Publication number
DK2090582T3
DK2090582T3 DK09155033.5T DK09155033T DK2090582T3 DK 2090582 T3 DK2090582 T3 DK 2090582T3 DK 09155033 T DK09155033 T DK 09155033T DK 2090582 T3 DK2090582 T3 DK 2090582T3
Authority
DK
Denmark
Prior art keywords
factor viii
proteins
binding molecules
human factor
human
Prior art date
Application number
DK09155033.5T
Other languages
English (en)
Inventor
Jinan Yu
Daniel M Potter
Brian D Kelley
Jeffrey S Deetz
James E Booth
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Application granted granted Critical
Publication of DK2090582T3 publication Critical patent/DK2090582T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Reciprocating Pumps (AREA)
DK09155033.5T 1999-01-04 2000-01-03 Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner DK2090582T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/224,785 US6197526B1 (en) 1999-01-04 1999-01-04 Polypeptides for binding human factor VIII and fragments of human factor VIII
EP06009040A EP1705183B1 (en) 1999-01-04 2000-01-03 Binding molecules for human factor VIII and factor VIII-like proteins

Publications (1)

Publication Number Publication Date
DK2090582T3 true DK2090582T3 (da) 2012-10-15

Family

ID=22842198

Family Applications (4)

Application Number Title Priority Date Filing Date
DK10182747.5T DK2301953T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler til human faktor VIII og faktor VIII-lignende proteiner
DK06009040T DK1705183T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler for human faktor VIII og faktor VIII-lignende proteiner
DK09155033.5T DK2090582T3 (da) 1999-01-04 2000-01-03 Bindende molekyler til human faktor VIII- og faktor VIII-lignende proteiner
DK10182741.8T DK2298791T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler for human faktor VIII og faktor VIII-lignende proteiner

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK10182747.5T DK2301953T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler til human faktor VIII og faktor VIII-lignende proteiner
DK06009040T DK1705183T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler for human faktor VIII og faktor VIII-lignende proteiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10182741.8T DK2298791T3 (da) 1999-01-04 2000-01-03 Bindingsmolekyler for human faktor VIII og faktor VIII-lignende proteiner

Country Status (12)

Country Link
US (2) US6197526B1 (da)
EP (5) EP2298791B8 (da)
JP (3) JP4733272B2 (da)
AT (1) ATE433992T1 (da)
AU (3) AU769745B2 (da)
CA (1) CA2354599C (da)
DE (1) DE60042430D1 (da)
DK (4) DK2301953T3 (da)
ES (4) ES2499040T3 (da)
HK (4) HK1038756A1 (da)
PT (3) PT1705183E (da)
WO (1) WO2000040602A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820796B2 (en) * 1998-03-12 2010-10-26 Genetics Institute, Llc. Methods for producing Factor VIII proteins
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) * 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
EP1504265B1 (en) * 2002-04-29 2011-11-30 Affibody AB Sandwich assay
US20090215025A1 (en) * 2005-12-07 2009-08-27 Technische Universitat Munchen Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
CA2684801C (en) 2007-04-04 2017-10-10 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
MX2010001363A (es) 2007-08-09 2010-03-09 Syntonix Pharmaceuticals Inc Peptidos inmunomoduladores.
AR071478A1 (es) * 2008-04-17 2010-06-23 Baxter Healthcare Sa Peptidos de bajo peso molecular con actividad procoagulante para el tratamiento de pacientes con deficiencia de factor v (fv), fvii, fviii, fx y/o fxi
US20100048488A1 (en) * 2008-08-01 2010-02-25 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
EP2717898B1 (en) * 2011-06-10 2018-12-19 Bioverativ Therapeutics Inc. Pro-coagulant compounds and methods of use thereof
EP3071515A2 (en) 2013-11-18 2016-09-28 Rubius Therapeutics, Inc. Synthetic membrane-receiver complexes
CN116731197A (zh) * 2016-09-19 2023-09-12 豪夫迈·罗氏有限公司 基于补体因子的亲和层析
KR20230143193A (ko) 2017-08-04 2023-10-11 다케다 야쿠힌 고교 가부시키가이샤 항체-수지 커플링 장치 및 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
JPH0788399B2 (ja) 1985-04-12 1995-09-27 ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド 新規プロコアギュラント蛋白質
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DE68927933T2 (de) * 1988-09-02 1997-08-14 Dyax Corp Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
SE468050C (sv) * 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
WO1992017192A1 (en) * 1991-03-27 1992-10-15 The Scripps Research Institute Therapeutic fragments of von willebrand factor
WO1997035196A1 (en) * 1996-03-20 1997-09-25 Dyax Corp. Engineering affinity ligands for macromolecules
JP2000512981A (ja) 1996-06-06 2000-10-03 ラ ホヤ ファーマシューティカル カンパニー ａＰＬ免疫応答性ペプチド、その結合体およびａＰＬ抗体媒介病理のための処置方法
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
WO1999058680A2 (en) * 1998-05-08 1999-11-18 Stichting Sanquin Bloedvoorziening Method for diagnosis and treatment of haemophilia a patients with an inhibitor
US5994310A (en) 1998-09-03 1999-11-30 Bayer Corporation Peptide ligands for affinity purification of human Factor VIII
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII

Also Published As

Publication number Publication date
EP1147128A1 (en) 2001-10-24
DE60042430D1 (de) 2009-07-30
AU2004201830B2 (en) 2007-04-05
AU769745B2 (en) 2004-02-05
ES2524965T3 (es) 2014-12-16
DK2298791T3 (da) 2014-12-08
EP1705183B1 (en) 2009-06-17
EP2298791A1 (en) 2011-03-23
ATE433992T1 (de) 2009-07-15
EP2090582A2 (en) 2009-08-19
US20010014456A1 (en) 2001-08-16
WO2000040602A1 (en) 2000-07-13
JP5368371B2 (ja) 2013-12-18
EP2301953B1 (en) 2014-07-30
EP2090582B1 (en) 2012-09-19
PT2298791E (pt) 2014-12-16
EP2090582A3 (en) 2009-11-11
US6197526B1 (en) 2001-03-06
JP2013079272A (ja) 2013-05-02
JP5572207B2 (ja) 2014-08-13
CA2354599A1 (en) 2000-07-13
HK1155182A1 (en) 2012-05-11
ES2328722T3 (es) 2009-11-17
US6492105B2 (en) 2002-12-10
HK1131398A1 (en) 2010-01-22
PT2301953E (pt) 2014-09-15
HK1038756A1 (zh) 2002-03-28
JP2002536297A (ja) 2002-10-29
HK1155756A1 (en) 2012-05-25
ES2499040T3 (es) 2014-09-26
DK2301953T3 (da) 2014-09-22
AU2598200A (en) 2000-07-24
JP4733272B2 (ja) 2011-07-27
PT1705183E (pt) 2009-07-31
CA2354599C (en) 2013-03-12
EP2301953A1 (en) 2011-03-30
EP1705183A1 (en) 2006-09-27
AU2004201810A1 (en) 2004-05-27
ES2390360T3 (es) 2012-11-12
AU2004201830A1 (en) 2004-05-27
JP2010254694A (ja) 2010-11-11
DK1705183T3 (da) 2009-10-19
EP2298791B8 (en) 2014-12-24
EP2298791B1 (en) 2014-11-12
EP1147128A4 (en) 2004-10-13

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