HK1038756A1 - 人類因子viii及類似因子viii蛋白用的黏合分子 - Google Patents

人類因子viii及類似因子viii蛋白用的黏合分子 Download PDF

Info

Publication number
HK1038756A1
HK1038756A1 HK02100182.6A HK02100182A HK1038756A1 HK 1038756 A1 HK1038756 A1 HK 1038756A1 HK 02100182 A HK02100182 A HK 02100182A HK 1038756 A1 HK1038756 A1 HK 1038756A1
Authority
HK
Hong Kong
Prior art keywords
factor viii
proteins
binding molecules
human factor
human
Prior art date
Application number
HK02100182.6A
Other languages
English (en)
Chinese (zh)
Inventor
Yu Jinan
Daniel Potter M.
D. Kelley Brian
S. Deetz Jeffrey
E. Booth James
Original Assignee
Dyax Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp. filed Critical Dyax Corp.
Priority to HK07100794.1A priority Critical patent/HK1093750B/en
Publication of HK1038756A1 publication Critical patent/HK1038756A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Reciprocating Pumps (AREA)
HK02100182.6A 1999-01-04 2000-01-03 人類因子viii及類似因子viii蛋白用的黏合分子 HK1038756A1 (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HK07100794.1A HK1093750B (en) 1999-01-04 2002-01-10 Binding molecules for human factor viii and factor viii-like proteins

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US224785 1981-01-13
US09/224,785 US6197526B1 (en) 1999-01-04 1999-01-04 Polypeptides for binding human factor VIII and fragments of human factor VIII
PCT/US2000/000043 WO2000040602A1 (en) 1999-01-04 2000-01-03 Binding molecules for human factor viii and factor viii-like proteins

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK07100794.1A Division HK1093750B (en) 1999-01-04 2002-01-10 Binding molecules for human factor viii and factor viii-like proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK07100794.1A Addition HK1093750B (en) 1999-01-04 2002-01-10 Binding molecules for human factor viii and factor viii-like proteins

Publications (1)

Publication Number Publication Date
HK1038756A1 true HK1038756A1 (zh) 2002-03-28

Family

ID=22842198

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100182.6A HK1038756A1 (zh) 1999-01-04 2000-01-03 人類因子viii及類似因子viii蛋白用的黏合分子

Country Status (12)

Country Link
US (2) US6197526B1 (enExample)
EP (5) EP1705183B1 (enExample)
JP (3) JP4733272B2 (enExample)
AT (1) ATE433992T1 (enExample)
AU (3) AU769745B2 (enExample)
CA (1) CA2354599C (enExample)
DE (1) DE60042430D1 (enExample)
DK (4) DK1705183T3 (enExample)
ES (4) ES2390360T3 (enExample)
HK (1) HK1038756A1 (enExample)
PT (3) PT1705183E (enExample)
WO (1) WO2000040602A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820796B2 (en) * 1998-03-12 2010-10-26 Genetics Institute, Llc. Methods for producing Factor VIII proteins
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) * 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FR2830865B1 (fr) 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
WO2003093821A1 (en) * 2002-04-29 2003-11-13 Affibody Ab Sandwich assay and kit
WO2007065691A2 (en) * 2005-12-07 2007-06-14 Technische Universität München Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
WO2008124107A1 (en) 2007-04-04 2008-10-16 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
CA2694824A1 (en) 2007-08-09 2009-02-12 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
AR071478A1 (es) 2008-04-17 2010-06-23 Baxter Healthcare Sa Peptidos de bajo peso molecular con actividad procoagulante para el tratamiento de pacientes con deficiencia de factor v (fv), fvii, fviii, fx y/o fxi
US20100048488A1 (en) * 2008-08-01 2010-02-25 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
CA2838833A1 (en) * 2011-06-10 2012-12-13 Biogen Idec Ma Inc. Pro-coagulant compounds and methods of use thereof
BR112016011195A2 (pt) 2013-11-18 2017-09-19 Rubius Therapeutics Inc Células eritroides enucleadas e seus métodos de fabricação, composição farmacêutica e seu uso, uso de uma população de células eritroides, biorreator, mistura de células e dispositivo médico
CN116731197A (zh) 2016-09-19 2023-09-12 豪夫迈·罗氏有限公司 基于补体因子的亲和层析
CA3301165A1 (en) 2017-08-04 2026-03-02 Takeda Pharmaceutical Company Limited Antibody-resin coupling apparatus and methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
MX9203440A (es) 1985-04-12 1992-07-01 Genetics Inst Proteinas procoagulantes novedosas.
DE68927933T2 (de) * 1988-09-02 1997-08-14 Dyax Corp Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
SE468050C (sv) * 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
WO1992017192A1 (en) * 1991-03-27 1992-10-15 The Scripps Research Institute Therapeutic fragments of von willebrand factor
IL126045A0 (en) * 1996-03-20 1999-05-09 Dyax Corp Purification of tissue plasminogen activator (tpa)
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
EP0954531A1 (en) 1996-06-06 1999-11-10 Lajolla Pharmaceutical Company aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES
AU760678B2 (en) * 1998-05-08 2003-05-22 Stichting Sanquin Bloedvoorziening Method for diagnosis and treatment of haemophilia a patients with an inhibitor
US5994310A (en) 1998-09-03 1999-11-30 Bayer Corporation Peptide ligands for affinity purification of human Factor VIII
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII

Also Published As

Publication number Publication date
DK2301953T3 (da) 2014-09-22
WO2000040602A1 (en) 2000-07-13
ES2499040T3 (es) 2014-09-26
EP1705183A1 (en) 2006-09-27
AU769745B2 (en) 2004-02-05
EP2090582A2 (en) 2009-08-19
AU2004201830B2 (en) 2007-04-05
HK1155756A1 (en) 2012-05-25
PT2301953E (pt) 2014-09-15
DK2298791T3 (en) 2014-12-08
JP5368371B2 (ja) 2013-12-18
ES2524965T3 (es) 2014-12-16
PT1705183E (pt) 2009-07-31
CA2354599A1 (en) 2000-07-13
JP5572207B2 (ja) 2014-08-13
US20010014456A1 (en) 2001-08-16
DK2090582T3 (da) 2012-10-15
EP2301953A1 (en) 2011-03-30
AU2598200A (en) 2000-07-24
HK1131398A1 (en) 2010-01-22
JP2013079272A (ja) 2013-05-02
JP2002536297A (ja) 2002-10-29
US6492105B2 (en) 2002-12-10
HK1155182A1 (en) 2012-05-11
JP4733272B2 (ja) 2011-07-27
US6197526B1 (en) 2001-03-06
EP2298791B1 (en) 2014-11-12
PT2298791E (pt) 2014-12-16
AU2004201810A1 (en) 2004-05-27
EP2301953B1 (en) 2014-07-30
EP2298791A1 (en) 2011-03-23
EP1147128A4 (en) 2004-10-13
EP2298791B8 (en) 2014-12-24
DK1705183T3 (da) 2009-10-19
DE60042430D1 (de) 2009-07-30
ES2390360T3 (es) 2012-11-12
JP2010254694A (ja) 2010-11-11
ATE433992T1 (de) 2009-07-15
EP2090582B1 (en) 2012-09-19
EP2090582A3 (en) 2009-11-11
EP1147128A1 (en) 2001-10-24
ES2328722T3 (es) 2009-11-17
AU2004201830A1 (en) 2004-05-27
EP1705183B1 (en) 2009-06-17
CA2354599C (en) 2013-03-12

Similar Documents

Publication Publication Date Title
EP2298791B8 (en) Binding molecules for human factor VIII and factor VIII-like proteins
HK1044966A1 (zh) C端蛋白标签
EP2267019A3 (en) Binding polypeptides for B lymphocyte stimulator protein (BLyS)
WO2005047459A3 (en) Sars nucleic acids, proteins, antibodies, and uses thereof
WO1997045746A3 (en) Prion protein binding proteins and uses thereof
ZA975588B (en) Isolated nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof.
WO2000068424A3 (en) Means for detecting and treating pathologies linked to fgfr3
ZA9710163B (en) Novel carboxylesterase nucleic acid molecules, proteins and uses thereof.
PL353069A1 (en) Conjugates and methods for the production thereof, and their use for transporting molecules via biological membranes
AU2001240662A1 (en) Method for the esr-spectroscopic detection of changes in the transport properties of albumin in an albumin-containing sample, esr-spectrometer for carrying out said method, and use of the method for diagnostic purposes and for controlling albumin-containing preparations
AU2001253804A1 (en) Isolated human transporter proteins, nucleic acid molecules encoding the same, and uses thereof
WO2000073345A3 (en) Antibodies specific for mycobacterial polypeptides and uses thereof
AU2001229508A1 (en) Nucleic acids, proteins, and antibodies
WO2000057188A3 (fr) Proteines associees a un cancer mammaire et procede de detection de ces proteines
EP1186662A3 (en) Prion binding proteins and uses thereof
WO2001021794A3 (en) Smad associating polypeptides
AU2001293665A1 (en) Method for quantitatively determining the available binding capacity in an aqueous protein solution
WO2002032937A3 (en) Neuromedin u delta
HK1057093A (en) Affinity selected signature peptides for protein identification and quantification
AU2001237953A1 (en) Nucleic acids, proteins, and antibodies
AU2001237955A1 (en) Nucleic acids, proteins, and antibodies
AU2001236460A1 (en) Nucleic acids, proteins, and antibodies
AU2001230958A1 (en) Nucleic acids, proteins, and antibodies
AU2001236459A1 (en) Nucleic acids, proteins, and antibodies
AU2001239726A1 (en) Nucleic acids, proteins, and antibodies