WO2000073345A3 - Antibodies specific for mycobacterial polypeptides and uses thereof - Google Patents

Antibodies specific for mycobacterial polypeptides and uses thereof Download PDF

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Publication number
WO2000073345A3
WO2000073345A3 PCT/US2000/014546 US0014546W WO0073345A3 WO 2000073345 A3 WO2000073345 A3 WO 2000073345A3 US 0014546 W US0014546 W US 0014546W WO 0073345 A3 WO0073345 A3 WO 0073345A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibodies specific
mycobacterial polypeptides
mycobacterial
polypeptides
antibodies
Prior art date
Application number
PCT/US2000/014546
Other languages
French (fr)
Other versions
WO2000073345A2 (en
Inventor
Mary Haak-Frendscho
Christopher Landowski
Scott Lesley
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Priority to AU52940/00A priority Critical patent/AU5294000A/en
Publication of WO2000073345A2 publication Critical patent/WO2000073345A2/en
Publication of WO2000073345A3 publication Critical patent/WO2000073345A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides antibodies specific for mycobacterial polypeptides, and methods which employ the antibodies.
PCT/US2000/014546 1999-05-28 2000-05-26 Antibodies specific for mycobacterial polypeptides and uses thereof WO2000073345A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU52940/00A AU5294000A (en) 1999-05-28 2000-05-26 Antibodies specific for mycobacterial polypeptides and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32220299A 1999-05-28 1999-05-28
US09/322,202 1999-05-28

Publications (2)

Publication Number Publication Date
WO2000073345A2 WO2000073345A2 (en) 2000-12-07
WO2000073345A3 true WO2000073345A3 (en) 2001-05-25

Family

ID=23253864

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/014546 WO2000073345A2 (en) 1999-05-28 2000-05-26 Antibodies specific for mycobacterial polypeptides and uses thereof

Country Status (2)

Country Link
AU (1) AU5294000A (en)
WO (1) WO2000073345A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129679A1 (en) * 2002-01-10 2003-07-10 Siddiqi Salman H. Methods and devices for collecting and preparing specimens for detection of mycobacteria and antigens
EP1674868A1 (en) * 2004-12-21 2006-06-28 Chang Gung University (a university of Taiwan) Method and device for detection of mycobacterium tuberculosis antigens in biological fluids
GB2433740A (en) * 2005-12-23 2007-07-04 Rapid Biosensor Systems Ltd Detection of tuberculosis infection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0499003A1 (en) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
WO1998004918A1 (en) * 1996-07-26 1998-02-05 Case Western Reserve University Detection of microbacteria
WO1998029132A1 (en) * 1996-12-31 1998-07-09 New York University Early detection of mycobacterial disease
WO1998031388A1 (en) * 1997-01-21 1998-07-23 Regents Of The University Of California Abundant extracellular products and methods for their production and use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0499003A1 (en) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
WO1998004918A1 (en) * 1996-07-26 1998-02-05 Case Western Reserve University Detection of microbacteria
WO1998029132A1 (en) * 1996-12-31 1998-07-09 New York University Early detection of mycobacterial disease
WO1998031388A1 (en) * 1997-01-21 1998-07-23 Regents Of The University Of California Abundant extracellular products and methods for their production and use

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ABOU-ZEID C ET AL: "GENETIC AND IMMUNOLOGICAL ANALYSIS OF MYCOBACTERIUM-TUBERCULOSIS FIBRONECTIN-BINDING PROTEINS", INFECTION AND IMMUNITY, vol. 59, no. 8, 1991, pages 2712 - 2718, XP000943330, ISSN: 0019-9567 *
BENTLEY-HIBBERT STUART I ET AL: "Pathophysiology of antigen 85 in patients with active tuberculosis: Antigen 85 circulates as complexes with fibronectin and immunoglobulin G.", INFECTION AND IMMUNITY, vol. 67, no. 2, February 1999 (1999-02-01), pages 581 - 588, XP000943336, ISSN: 0019-9567 *
DROWART A ET AL: "IgG humoral response against the antigen 85 complex homologues in leprosy.", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, vol. 40, no. 6, 1994, pages 643 - 647, XP000943363, ISSN: 0300-9475 *
WIKER HARALD G ET AL: "The antigen 85 complex: A major secretion product of Mycobacterium tuberculosis.", MICROBIOLOGICAL REVIEWS, vol. 56, no. 4, 1992, pages 648 - 661, XP000572193, ISSN: 0146-0749 *

Also Published As

Publication number Publication date
WO2000073345A2 (en) 2000-12-07
AU5294000A (en) 2000-12-18

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