ZA200307365B - Antibodies specific for CD44V6. - Google Patents

Antibodies specific for CD44V6.

Info

Publication number
ZA200307365B
ZA200307365B ZA200307365A ZA200307365A ZA200307365B ZA 200307365 B ZA200307365 B ZA 200307365B ZA 200307365 A ZA200307365 A ZA 200307365A ZA 200307365 A ZA200307365 A ZA 200307365A ZA 200307365 B ZA200307365 B ZA 200307365B
Authority
ZA
South Africa
Prior art keywords
cd44v6
antibodies specific
antibodies
specific
Prior art date
Application number
ZA200307365A
Inventor
Guenther Adolf
Elinborg Ostermann
Erik Patzelt
Marlies Sproll
Karl-Heinz Heider
John J Miglietta
Augustinus Antonius Mar Dongen
Original Assignee
Boehringer Ingelheim Int
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Int
Publication of ZA200307365B publication Critical patent/ZA200307365B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
ZA200307365A 2001-05-18 2003-09-22 Antibodies specific for CD44V6. ZA200307365B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01112237 2001-05-18

Publications (1)

Publication Number Publication Date
ZA200307365B true ZA200307365B (en) 2004-05-10

Family

ID=33442672

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200307365A ZA200307365B (en) 2001-05-18 2003-09-22 Antibodies specific for CD44V6.

Country Status (18)

Country Link
EP (1) EP1397387A1 (en)
JP (1) JP2005504517A (en)
CN (1) CN1541226A (en)
AR (1) AR036154A1 (en)
BR (1) BR0210905A (en)
CA (1) CA2443437A1 (en)
CZ (1) CZ20033476A3 (en)
EA (1) EA200301169A1 (en)
EC (1) ECSP034838A (en)
EE (1) EE200300569A (en)
HU (1) HUP0400030A3 (en)
MX (1) MXPA03010523A (en)
PE (1) PE20021098A1 (en)
PL (1) PL365735A1 (en)
SK (1) SK15592003A3 (en)
WO (1) WO2002094879A1 (en)
YU (1) YU91403A (en)
ZA (1) ZA200307365B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7947496B2 (en) 1999-10-08 2011-05-24 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20050100542A1 (en) 1999-10-08 2005-05-12 Young David S. Cytotoxicity mediation of cells evidencing surface expression of CD44
US8071072B2 (en) 1999-10-08 2011-12-06 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US8048416B2 (en) 1999-10-08 2011-11-01 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7189397B2 (en) * 1999-10-08 2007-03-13 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7084257B2 (en) 2001-10-05 2006-08-01 Amgen Inc. Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
US20050232919A1 (en) 2004-02-12 2005-10-20 Morphotek, Inc. Monoclonal antibodies that specifically block biological activity of a tumor antigen
JP4949373B2 (en) 2005-03-10 2012-06-06 モルフォテック、インク. Anti-mesothelin antibody
CA2607444C (en) 2005-04-22 2015-03-10 Morphotek, Inc. Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells
AU2008265974B2 (en) * 2007-06-13 2013-08-29 Ares Trading S.A. Use of TACI-Ig fusion protein such as atacicept for the manufacture of a medicament for treating Lupus Erythematosus
EP2009028A1 (en) * 2007-06-27 2008-12-31 Monoclonal Antibodies Therapeutics Combination of a conventional anti-cancer treatment with anti-CD44 antibody administration for treating solid tumors
SG10201505118PA (en) 2010-02-04 2015-07-30 Hoffmann La Roche A Monoclonal Antibody To Cd44 For Use In The Treatment Of Head And Neck Squamous Cell Carcinoma
CN102337298B (en) * 2011-08-19 2013-11-06 黄开红 Immune nano-carrier for conveying siRNA (small interfering Ribonucleic Acid) and preparation method and application thereof
US20140335084A1 (en) 2011-12-06 2014-11-13 Hoffmann-La Roche Inc. Antibody formulation
WO2017215637A1 (en) * 2016-06-15 2017-12-21 李翀 Human endometrial cancer marker, antibody, and application of antibody
CN107556388A (en) * 2016-06-30 2018-01-09 中国科学院深圳先进技术研究院 The double targeting antibodies of anti-CD44v6 and CD3 specificity, the minicircle dna containing this pair of targeting antibodies expression cassette and application
WO2022187591A1 (en) * 2021-03-05 2022-09-09 Go Therapeutics, Inc. Anti-glyco-cd44 antibodies and their uses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
EP0438310A1 (en) * 1990-01-19 1991-07-24 Merck & Co. Inc. Method for producing recombinant immunoglobuline
GB9020282D0 (en) * 1990-09-17 1990-10-31 Gorman Scott D Altered antibodies and their preparation
EP0672130A1 (en) * 1992-11-20 1995-09-20 Isis Innovation Limited Peptide corresponding to cd44 exon 6, antibodies specific for said peptide and use of these antibodies for diagnosis of tumors
UA58482C2 (en) * 1994-06-08 2003-08-15 Бьорінгер Інгельхайм Інтернаціональ Гмбх MONOCLONAL ANTIBODY VFF-18 AGAINST CD44v6 AND ITS FRAGMENTS
UY24389A1 (en) * 1995-12-06 2001-10-25 Karlsruhe Forschzent PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF FLAT EPITHELIUM CARCINOMA

Also Published As

Publication number Publication date
CZ20033476A3 (en) 2004-05-12
YU91403A (en) 2006-05-25
EA200301169A1 (en) 2004-06-24
CA2443437A1 (en) 2002-11-28
BR0210905A (en) 2004-06-08
HUP0400030A3 (en) 2006-02-28
AR036154A1 (en) 2004-08-18
JP2005504517A (en) 2005-02-17
EE200300569A (en) 2004-04-15
PE20021098A1 (en) 2003-02-11
HUP0400030A2 (en) 2004-04-28
WO2002094879A1 (en) 2002-11-28
SK15592003A3 (en) 2004-06-08
PL365735A1 (en) 2005-01-10
CN1541226A (en) 2004-10-27
EP1397387A1 (en) 2004-03-17
ECSP034838A (en) 2003-12-24
MXPA03010523A (en) 2004-07-01

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