MXPA03010523A - Antibodies specific for cd44v6. - Google Patents
Antibodies specific for cd44v6.Info
- Publication number
- MXPA03010523A MXPA03010523A MXPA03010523A MXPA03010523A MXPA03010523A MX PA03010523 A MXPA03010523 A MX PA03010523A MX PA03010523 A MXPA03010523 A MX PA03010523A MX PA03010523 A MXPA03010523 A MX PA03010523A MX PA03010523 A MXPA03010523 A MX PA03010523A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- antibody proteins
- cd44v6
- antibodies specific
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
Abstract
The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44 gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01112237 | 2001-05-18 | ||
US23514701P | 2001-09-26 | 2001-09-26 | |
PCT/EP2002/005467 WO2002094879A1 (en) | 2001-05-18 | 2002-05-17 | Antibodies specific for cd44v6 |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03010523A true MXPA03010523A (en) | 2004-07-01 |
Family
ID=33442672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03010523A MXPA03010523A (en) | 2001-05-18 | 2002-05-17 | Antibodies specific for cd44v6. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1397387A1 (en) |
JP (1) | JP2005504517A (en) |
CN (1) | CN1541226A (en) |
AR (1) | AR036154A1 (en) |
BR (1) | BR0210905A (en) |
CA (1) | CA2443437A1 (en) |
CZ (1) | CZ20033476A3 (en) |
EA (1) | EA200301169A1 (en) |
EC (1) | ECSP034838A (en) |
EE (1) | EE200300569A (en) |
HU (1) | HUP0400030A3 (en) |
MX (1) | MXPA03010523A (en) |
PE (1) | PE20021098A1 (en) |
PL (1) | PL365735A1 (en) |
SK (1) | SK15592003A3 (en) |
WO (1) | WO2002094879A1 (en) |
YU (1) | YU91403A (en) |
ZA (1) | ZA200307365B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7189397B2 (en) * | 1999-10-08 | 2007-03-13 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US8048416B2 (en) | 1999-10-08 | 2011-11-01 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US20050100542A1 (en) | 1999-10-08 | 2005-05-12 | Young David S. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US8071072B2 (en) | 1999-10-08 | 2011-12-06 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US7947496B2 (en) | 1999-10-08 | 2011-05-24 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US7084257B2 (en) | 2001-10-05 | 2006-08-01 | Amgen Inc. | Fully human antibody Fab fragments with human interferon-gamma neutralizing activity |
EP3101034A1 (en) | 2004-02-12 | 2016-12-07 | Morphotek, Inc. | Monoclonal antibodies that specifically bind to folate receptor alpha |
JP4949373B2 (en) | 2005-03-10 | 2012-06-06 | モルフォテック、インク. | Anti-mesothelin antibody |
WO2006116592A2 (en) | 2005-04-22 | 2006-11-02 | Morphotek, Inc. | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells |
AU2008265974B2 (en) * | 2007-06-13 | 2013-08-29 | Ares Trading S.A. | Use of TACI-Ig fusion protein such as atacicept for the manufacture of a medicament for treating Lupus Erythematosus |
EP2009028A1 (en) * | 2007-06-27 | 2008-12-31 | Monoclonal Antibodies Therapeutics | Combination of a conventional anti-cancer treatment with anti-CD44 antibody administration for treating solid tumors |
CA2786337A1 (en) | 2010-02-04 | 2011-08-11 | F. Hoffmann-La Roche Ag | A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma |
CN102337298B (en) * | 2011-08-19 | 2013-11-06 | 黄开红 | Immune nano-carrier for conveying siRNA (small interfering Ribonucleic Acid) and preparation method and application thereof |
US20140335084A1 (en) | 2011-12-06 | 2014-11-13 | Hoffmann-La Roche Inc. | Antibody formulation |
WO2017215637A1 (en) * | 2016-06-15 | 2017-12-21 | 李翀 | Human endometrial cancer marker, antibody, and application of antibody |
CN107556388A (en) * | 2016-06-30 | 2018-01-09 | 中国科学院深圳先进技术研究院 | The double targeting antibodies of anti-CD44v6 and CD3 specificity, the minicircle dna containing this pair of targeting antibodies expression cassette and application |
EP4301782A1 (en) * | 2021-03-05 | 2024-01-10 | Go Therapeutics, Inc. | Anti-glyco-cd44 antibodies and their uses |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
IL162181A (en) * | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
EP0438310A1 (en) * | 1990-01-19 | 1991-07-24 | Merck & Co. Inc. | Method for producing recombinant immunoglobuline |
GB9020282D0 (en) * | 1990-09-17 | 1990-10-31 | Gorman Scott D | Altered antibodies and their preparation |
WO1994012631A1 (en) * | 1992-11-20 | 1994-06-09 | Isis Innovation Limited | Peptide corresponding to cd44 exon 6, antibodies specific for said peptide and use of these antibodies for diagnosis of tumors |
UA58482C2 (en) * | 1994-06-08 | 2003-08-15 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | MONOCLONAL ANTIBODY VFF-18 AGAINST CD44v6 AND ITS FRAGMENTS |
UY24389A1 (en) * | 1995-12-06 | 2001-10-25 | Karlsruhe Forschzent | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF FLAT EPITHELIUM CARCINOMA |
-
2002
- 2002-05-17 MX MXPA03010523A patent/MXPA03010523A/en unknown
- 2002-05-17 PL PL02365735A patent/PL365735A1/en not_active Application Discontinuation
- 2002-05-17 AR ARP020101830A patent/AR036154A1/en not_active Suspension/Interruption
- 2002-05-17 CZ CZ20033476A patent/CZ20033476A3/en unknown
- 2002-05-17 CN CNA028101561A patent/CN1541226A/en active Pending
- 2002-05-17 WO PCT/EP2002/005467 patent/WO2002094879A1/en not_active Application Discontinuation
- 2002-05-17 EE EEP200300569A patent/EE200300569A/en unknown
- 2002-05-17 EP EP02735364A patent/EP1397387A1/en not_active Ceased
- 2002-05-17 HU HU0400030A patent/HUP0400030A3/en unknown
- 2002-05-17 JP JP2002592353A patent/JP2005504517A/en active Pending
- 2002-05-17 SK SK1559-2003A patent/SK15592003A3/en not_active Application Discontinuation
- 2002-05-17 CA CA002443437A patent/CA2443437A1/en not_active Abandoned
- 2002-05-17 BR BR0210905-0A patent/BR0210905A/en not_active Expired - Fee Related
- 2002-05-17 PE PE2002000422A patent/PE20021098A1/en not_active Application Discontinuation
- 2002-05-17 EA EA200301169A patent/EA200301169A1/en unknown
- 2002-05-17 YU YU91403A patent/YU91403A/en unknown
-
2003
- 2003-09-22 ZA ZA200307365A patent/ZA200307365B/en unknown
- 2003-11-10 EC EC2003004838A patent/ECSP034838A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2005504517A (en) | 2005-02-17 |
WO2002094879A1 (en) | 2002-11-28 |
SK15592003A3 (en) | 2004-06-08 |
CZ20033476A3 (en) | 2004-05-12 |
PE20021098A1 (en) | 2003-02-11 |
ZA200307365B (en) | 2004-05-10 |
BR0210905A (en) | 2004-06-08 |
CA2443437A1 (en) | 2002-11-28 |
HUP0400030A3 (en) | 2006-02-28 |
EE200300569A (en) | 2004-04-15 |
CN1541226A (en) | 2004-10-27 |
EP1397387A1 (en) | 2004-03-17 |
EA200301169A1 (en) | 2004-06-24 |
HUP0400030A2 (en) | 2004-04-28 |
PL365735A1 (en) | 2005-01-10 |
YU91403A (en) | 2006-05-25 |
AR036154A1 (en) | 2004-08-18 |
ECSP034838A (en) | 2003-12-24 |
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