AU3425700A - Non-ribosomal peptide synthetases, method for producing same and the use thereof - Google Patents

Non-ribosomal peptide synthetases, method for producing same and the use thereof

Info

Publication number
AU3425700A
AU3425700A AU34257/00A AU3425700A AU3425700A AU 3425700 A AU3425700 A AU 3425700A AU 34257/00 A AU34257/00 A AU 34257/00A AU 3425700 A AU3425700 A AU 3425700A AU 3425700 A AU3425700 A AU 3425700A
Authority
AU
Australia
Prior art keywords
producing same
ribosomal peptide
peptide synthetases
synthetases
ribosomal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34257/00A
Inventor
Dirk Konz
Mohamed A. Marahiel
Henning Mootz
Torsten Stachelhaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MOHAMED A MARAHIEL
Original Assignee
MOHAMED A MARAHIEL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MOHAMED A MARAHIEL filed Critical MOHAMED A MARAHIEL
Publication of AU3425700A publication Critical patent/AU3425700A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
AU34257/00A 1999-03-03 2000-02-28 Non-ribosomal peptide synthetases, method for producing same and the use thereof Abandoned AU3425700A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19909146A DE19909146A1 (en) 1999-03-03 1999-03-03 Process for the targeted biological synthesis of peptides
DE19909146 1999-03-03
PCT/EP2000/001652 WO2000052152A1 (en) 1999-03-03 2000-02-28 Non-ribosomal peptide synthetases, method for producing same and the use thereof

Publications (1)

Publication Number Publication Date
AU3425700A true AU3425700A (en) 2000-09-21

Family

ID=7899460

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34257/00A Abandoned AU3425700A (en) 1999-03-03 2000-02-28 Non-ribosomal peptide synthetases, method for producing same and the use thereof

Country Status (8)

Country Link
EP (1) EP1159416A1 (en)
JP (1) JP2002537806A (en)
CN (1) CN1342201A (en)
AU (1) AU3425700A (en)
CA (1) CA2364569A1 (en)
DE (1) DE19909146A1 (en)
IL (1) IL145004A0 (en)
WO (1) WO2000052152A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399789B1 (en) 1996-12-18 2002-06-04 Kosan Biosciences, Inc. Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides
CA2369633A1 (en) * 1999-04-16 2000-10-26 Kosan Biosciences, Inc. A multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides
DE19951196A1 (en) * 1999-10-22 2001-05-10 Mohamed A Marahiel Tailored peptide synthetases and their use
DE10340068A1 (en) * 2003-08-28 2005-03-24 TransMIT Gesellschaft für Technologietransfer mbH New inhibitors of non-ribosomal peptide synthetase adenylation domains useful in therapeutic compositions comprise aminoacyl sulfamoyl adenosine derivatives
EP1765374A4 (en) 2004-01-30 2010-11-03 Texas A & M Univ Sys Compositions, methods and uses for a novel family of peptides
ES2447491T3 (en) * 2006-10-05 2014-03-12 Dsm Sinochem Pharmaceuticals Netherlands B.V. Ss-lactam antibiotic production
US8945898B2 (en) * 2010-07-01 2015-02-03 Dsm Ip Assets B.V. Recombinant host cell with deficiency in non-ribosomal peptide synthase production
BR112015002621A2 (en) * 2012-08-06 2018-05-22 Danisco Us Inc fungal cells that produce reduced amounts of peptaibols
JP7101989B2 (en) 2015-08-05 2022-07-19 ヨハン ヴォルフガング ゲーテ ウニヴェルシテート Artificial nonribosomal peptide synthesizer
US11643643B2 (en) 2016-02-08 2023-05-09 Johann Wolfgang Goethe-Universität Frankfurt am Main Artificial non-ribosomal peptide synthases and their use
JP6908111B2 (en) * 2017-06-30 2021-07-21 日本電気株式会社 Predictor, Prediction Method, Prediction Program, and Gene Estimator
EP3511445A1 (en) 2018-01-15 2019-07-17 Johann Wolfgang Goethe-Universität Frankfurt System for the assembly and modification of non-ribosomal peptide synthases
CN111575251B (en) * 2020-05-29 2022-03-11 上海交通大学 Construction of dptC1 mutant for daptomycin biosynthesis
CN113278601B (en) * 2021-05-17 2022-07-08 浙江工业大学 Adenylylation protein A6 mutant and coding gene and application thereof
WO2024038117A1 (en) 2022-08-16 2024-02-22 Johann Wolfgang Goethe-Universität Frankfurt Method and means for engineering non-ribosomal peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264712B1 (en) * 1993-07-13 1996-10-04 Eniricerche Spa BIOLOGICAL SYNTHESIS METHOD OF PEPTIDES
IT1277466B1 (en) * 1995-08-09 1997-11-10 Eniricerche Spa ENGINEERED PEPTIDE SYNTHETASES AND THEIR USE FOR THE NON-RIBOSOMAL PRODUCTION OF PEPTIDES

Also Published As

Publication number Publication date
CA2364569A1 (en) 2000-09-08
WO2000052152A1 (en) 2000-09-08
CN1342201A (en) 2002-03-27
JP2002537806A (en) 2002-11-12
DE19909146A1 (en) 2000-09-28
IL145004A0 (en) 2002-06-30
EP1159416A1 (en) 2001-12-05

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase