JP4726296B2 - 創傷治癒のためのマトリックスタンパク質組成物 - Google Patents
創傷治癒のためのマトリックスタンパク質組成物 Download PDFInfo
- Publication number
- JP4726296B2 JP4726296B2 JP2000533139A JP2000533139A JP4726296B2 JP 4726296 B2 JP4726296 B2 JP 4726296B2 JP 2000533139 A JP2000533139 A JP 2000533139A JP 2000533139 A JP2000533139 A JP 2000533139A JP 4726296 B2 JP4726296 B2 JP 4726296B2
- Authority
- JP
- Japan
- Prior art keywords
- enamel matrix
- wound
- enamel
- kda
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/108—Specific proteins or polypeptides not covered by groups A61L24/102 - A61L24/106
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Surgery (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK27098 | 1998-02-27 | ||
| DK0270/98 | 1998-02-27 | ||
| US8155198P | 1998-04-13 | 1998-04-13 | |
| US60/081,551 | 1998-04-13 | ||
| DK199800270 | 1998-07-21 | ||
| DK60/081,551 | 1998-10-16 | ||
| DKPA199801328 | 1998-10-16 | ||
| DK199801328 | 1998-10-16 | ||
| DKPA199801328 | 1998-10-16 | ||
| PCT/IB1999/000337 WO1999043344A2 (en) | 1998-02-27 | 1999-02-26 | Matrix protein compositions for wound healing |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007131100A Division JP5024866B2 (ja) | 1998-02-27 | 2007-05-17 | 創傷治癒のためのマトリックスタンパク質組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002504520A JP2002504520A (ja) | 2002-02-12 |
| JP2002504520A5 JP2002504520A5 (https=) | 2005-07-21 |
| JP4726296B2 true JP4726296B2 (ja) | 2011-07-20 |
Family
ID=34395112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000533139A Expired - Lifetime JP4726296B2 (ja) | 1998-02-27 | 1999-02-26 | 創傷治癒のためのマトリックスタンパク質組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6503539B2 (https=) |
| JP (1) | JP4726296B2 (https=) |
| AR (1) | AR020055A1 (https=) |
| BR (1) | BRPI9908182C1 (https=) |
| PL (1) | PL204797B1 (https=) |
| RU (1) | RU2241489C2 (https=) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL137869A0 (en) * | 1998-02-27 | 2001-10-31 | Biora Bioex Ab | Matrix protein compositions for wound healing |
| US6884427B1 (en) * | 1999-02-08 | 2005-04-26 | Aderans Research Institute, Inc. | Filamentary means for introducing agents into tissue of a living host |
| US20030096740A1 (en) * | 1999-03-10 | 2003-05-22 | Lars Hammarstrom | Matrix protein compositions for induction of apoptosis |
| US6979670B1 (en) * | 1999-03-10 | 2005-12-27 | Biora Bioex Ab | Matrix protein compositions for grafting |
| HU230030B1 (hu) | 1999-10-08 | 2015-05-28 | Debiopharm International Sa | Fab I inhibitorok |
| US6821953B1 (en) * | 1999-12-16 | 2004-11-23 | University Of Southern California | Methods for treating and preventing damage to mucosal tissue |
| US7304030B2 (en) * | 2000-06-20 | 2007-12-04 | Biora Ab | Matrix protein composition for dentin regeneration |
| JP5095063B2 (ja) * | 2000-06-20 | 2012-12-12 | ストローマン ホールディング アーゲー | 象牙質再生に用いる基質タンパク質組成物 |
| JP4017977B2 (ja) * | 2000-08-08 | 2007-12-05 | アデランス リサーチ インスティテュート インコーポレイテッド | 組織工学で処置した毛髪用の台 |
| US7144729B2 (en) * | 2000-09-01 | 2006-12-05 | Dfb Pharmaceuticals, Inc. | Methods and compositions for tissue regeneration |
| US20040018228A1 (en) * | 2000-11-06 | 2004-01-29 | Afmedica, Inc. | Compositions and methods for reducing scar tissue formation |
| CA2434254C (en) * | 2001-01-12 | 2013-08-13 | Board Of Regents, The University Of Texas System | Novel antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces |
| US7033611B2 (en) * | 2001-02-23 | 2006-04-25 | Biora Bioex Ab | Matrix protein compositions for guided connective tissue growth |
| EP1560584B1 (en) * | 2001-04-06 | 2009-01-14 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
| CN100346823C (zh) * | 2001-09-14 | 2007-11-07 | 比奥拉比奥埃克斯公司 | 用于调节免疫反应的釉质基质蛋白组合物 |
| CA2473931C (en) * | 2002-01-23 | 2010-10-26 | Dentsply International, Inc. | Irrigation solution and methods for use |
| US20040068284A1 (en) * | 2002-01-29 | 2004-04-08 | Barrows Thomas H. | Method for stimulating hair growth and kit for carrying out said method |
| JP4948744B2 (ja) * | 2002-10-04 | 2012-06-06 | 允 深江 | 歯周組織再生剤、その有効成分抽出法、およびプラスミド |
| EP1575951B1 (en) * | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterocyclic compounds, methods of making them and their use in therapy |
| JP2004307454A (ja) * | 2003-02-21 | 2004-11-04 | Seikagaku Kogyo Co Ltd | 生理活性ペプチド及びこれを含有する薬剤 |
| US7494980B2 (en) * | 2003-03-10 | 2009-02-24 | The United States Of America As Represented By The Secretary Of The Army | Antimicrobial peptide and methods of use thereof |
| US8778889B2 (en) * | 2003-03-10 | 2014-07-15 | The United States Of America As Represented By The Secretary Of The Army | Antimicrobial decapeptide oral hygiene treatment |
| WO2004082586A2 (en) * | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
| HUE045608T2 (hu) * | 2003-06-06 | 2020-01-28 | Univ Texas | Antimikrobiális öblítõoldatok |
| WO2005000837A1 (en) * | 2003-06-19 | 2005-01-06 | Janssen Pharmaceutica N.V. | Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists |
| EP1680148A1 (en) * | 2003-10-21 | 2006-07-19 | Bioartificial Gel Technologies Inc. | Hydrogel-containing medical articles and methods of using and making the same |
| US20050125015A1 (en) * | 2003-12-04 | 2005-06-09 | Mcnally-Heintzelman Karen M. | Tissue-handling apparatus, system and method |
| US20050125033A1 (en) * | 2003-12-04 | 2005-06-09 | Mcnally-Heintzelman Karen M. | Wound closure apparatus |
| JP2007522835A (ja) * | 2004-01-20 | 2007-08-16 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 医療装置に消毒組成物をコーティングする、および含浸させる方法 |
| US7597885B2 (en) * | 2004-03-26 | 2009-10-06 | Aderans Research Institute, Inc. | Tissue engineered biomimetic hair follicle graft |
| US20050220821A1 (en) * | 2004-03-31 | 2005-10-06 | Allergan, Inc. | Pressure sore treatment |
| DK1828167T3 (da) * | 2004-06-04 | 2014-10-20 | Debiopharm Int Sa | Acrylamidderivater som antibiotiske midler |
| AR050212A1 (es) * | 2004-08-13 | 2006-10-04 | Aderans Res Inst Inc | Organogenesis a partir de celulas disociadas |
| RU2277933C2 (ru) * | 2004-09-21 | 2006-06-20 | Государственное образовательное учреждение высшего профессионального образования Курский государственный медицинский университет Министерства здравоохранения Российской Федерации | Иммобилизованная форма цефазолина для профилактики послеоперационных инфекционных осложнений в оториноларингологии |
| US7766658B2 (en) * | 2004-11-30 | 2010-08-03 | Align Technology, Inc. | Systems and methods for intra-oral diagnosis |
| US20060115782A1 (en) * | 2004-11-30 | 2006-06-01 | Chunhua Li | Systems and methods for coating a dental appliance |
| US20060115785A1 (en) * | 2004-11-30 | 2006-06-01 | Chunhua Li | Systems and methods for intra-oral drug delivery |
| US7947508B2 (en) * | 2004-11-30 | 2011-05-24 | Align Technology, Inc. | Systems and methods for intra-oral diagnosis |
| SE0403014D0 (sv) * | 2004-12-10 | 2004-12-10 | Straumann Holding Ag | New protein formulation |
| EP1830863A2 (en) * | 2004-12-10 | 2007-09-12 | Straumann Holding AG | Protein formulation |
| US7722900B2 (en) * | 2005-04-09 | 2010-05-25 | Yukiko Tanabe, legal representative | Effect of porcine sheath proteins on the regeneration activity of periodontal ligament |
| US20070048356A1 (en) * | 2005-08-31 | 2007-03-01 | Schorr Phillip A | Antimicrobial treatment of nonwoven materials for infection control |
| US20070048344A1 (en) * | 2005-08-31 | 2007-03-01 | Ali Yahiaoui | Antimicrobial composition |
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| US20070048358A1 (en) * | 2005-08-31 | 2007-03-01 | Schorr Phillip A | Antimicrobial substrates |
| US20070154621A1 (en) | 2005-11-18 | 2007-07-05 | Issam Raad | Methods for coating surfaces with antimicrobial agents |
| TW200803877A (en) * | 2005-11-22 | 2008-01-16 | Aderans Res Inst Inc | Hair grafts derived from plucked hair |
| WO2007062386A2 (en) * | 2005-11-22 | 2007-05-31 | Aderans Research Institute, Inc. | Hair follicle graft from tissue engineered skin |
| KR20080075027A (ko) * | 2005-12-05 | 2008-08-13 | 아피늄 파마슈티컬스, 인크. | Fabi 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물 |
| US20070135706A1 (en) * | 2005-12-13 | 2007-06-14 | Shimko Daniel A | Debridement method, device and kit |
| US20070148187A1 (en) * | 2005-12-27 | 2007-06-28 | Intact Enterprises, Inc. | Mastic gum composition for use as a dietary supplement in humans and animals |
| WO2008006083A2 (en) | 2006-07-07 | 2008-01-10 | Surmodics, Inc. | Beaded wound spacer device |
| JP5468899B2 (ja) | 2006-07-20 | 2014-04-09 | アフィニウム ファーマシューティカルズ, インク. | Fabiインヒビターとしてのアクリルアミド誘導体 |
| US7772213B2 (en) * | 2006-07-27 | 2010-08-10 | Nathan Strick | Composition for the treatment of inflammatory conditions |
| US8623842B2 (en) * | 2006-09-27 | 2014-01-07 | Hemostasis, Llc | Hemostatic agent and method |
| EP2125802A4 (en) | 2007-02-16 | 2014-08-20 | Debiopharm Int Sa | SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS |
| EP2120561A4 (en) | 2007-02-19 | 2012-11-21 | Plurogen Therapeutics Inc | COMPOSITIONS FOR TREATING BIOFILMS, AND METHODS FOR THEIR USE |
| US7985537B2 (en) * | 2007-06-12 | 2011-07-26 | Aderans Research Institute, Inc. | Methods for determining the hair follicle inductive properties of a composition |
| US20090202609A1 (en) * | 2008-01-06 | 2009-08-13 | Keough Steven J | Medical device with coating composition |
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| US8980243B2 (en) | 2009-05-19 | 2015-03-17 | Neal Koller | Surface active agent compositions and methods for enhancing oxygenation, reducing bacteria and improving wound healing at a site of treatment |
| US9192626B2 (en) * | 2009-06-10 | 2015-11-24 | American Silver, Llc | Dental uses of silver hydrosol |
| CN101991688A (zh) * | 2009-08-20 | 2011-03-30 | 徐荣祥 | 药物组合物在制备治疗糖尿病溃疡药物中的用途 |
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| JP5671618B2 (ja) | 2010-10-15 | 2015-02-18 | ストラウマン ホールディング アーゲー | Pgaを含んでなる新しいemd製剤 |
| BR112013030381B1 (pt) | 2011-05-27 | 2021-10-26 | University Of Washington Through Its Center For Commercialization | Produto de cuidado oral |
| AU2013279021C1 (en) | 2012-06-19 | 2017-03-16 | Debiopharm International Sa | Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide |
| US20140023979A1 (en) * | 2012-07-18 | 2014-01-23 | Maha Mohamed Fouad Mounir | Regeneration of ameloblast cells and dental enamel in vivo |
| JP6298468B2 (ja) | 2012-10-16 | 2018-03-20 | サーモディクス,インコーポレイテッド | 創傷充填デバイスおよび方法 |
| US20140186273A1 (en) * | 2012-12-27 | 2014-07-03 | University Of Southern California | Chitosan -Amelogenin Hydrogel for In Situ Enamel Growth |
| US20140272803A1 (en) * | 2013-03-14 | 2014-09-18 | Alan Nevins | Root canal for tissue in-growth |
| WO2014177602A1 (en) * | 2013-04-30 | 2014-11-06 | Straumann Holding Ag | Trap 63 |
| JP6483139B2 (ja) * | 2014-01-17 | 2019-03-13 | ストラウマン ホールディング アーゲー | 増強した安定性のemdの製造方法 |
| US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| AU2016209327A1 (en) | 2015-01-20 | 2017-08-10 | Plurogen Therapeutics, Llc | Compositions and methods of treating microbes |
| US9962465B2 (en) | 2015-07-07 | 2018-05-08 | University Of Southern California | Amelogenin-chitosan hydrogel for dentin hypersensitivity |
| US10952940B2 (en) | 2016-01-15 | 2021-03-23 | University Of Washington | Reagents and methods for mineralization of tooth enamel |
| RU2732224C9 (ru) | 2016-01-31 | 2021-06-18 | Медивунд Лтд. | Раноочищающая композиция для лечения ран |
| RS61312B1 (sr) | 2016-02-26 | 2021-02-26 | Debiopharm Int Sa | Lek za lečenje infekcija dijabetskog stopala |
| WO2017183018A1 (en) * | 2016-04-18 | 2017-10-26 | Mediwound Ltd | Methods of debridement of chronic wounds |
| TN2021000159A1 (en) | 2019-02-14 | 2023-04-04 | Debiopharm Int Sa | Afabicin formulation, method for making the same and uses thereof |
| SG11202113174SA (en) | 2019-06-14 | 2021-12-30 | Debiopharm Int Sa | Medicament and use thereof for treating bacterial infections involving biofilm |
| US11457996B2 (en) * | 2019-09-12 | 2022-10-04 | King Abdulaziz University | Dental pulp capping composition and method of preserving and regenerating capped pulp and dentin bridge |
| CZ308980B6 (cs) | 2020-01-24 | 2021-11-03 | Contipro A.S. | Dentální přípravek z vláken na bázi kyseliny hyaluronové s regulovatelnou biodegradabilitou |
| US20240269167A1 (en) * | 2020-12-21 | 2024-08-15 | Biointelligent Technology Systems Slu | A mucosal re-epithelialization composition |
| KR102802100B1 (ko) * | 2023-07-14 | 2025-05-02 | 주식회사 티앤알바이오팹 | 흡수성 체내 지혈 키트 및 흡수성 체내 지혈제 |
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|---|---|---|---|---|
| SU98529A1 (ru) * | 1952-04-04 | 1953-11-30 | Конструкторское Бюро Особое | Рабочее колесо центробежного погружного насоса |
| SU1398869A1 (ru) * | 1985-10-31 | 1988-05-30 | Московский медицинский стоматологический институт им.Н.А.Семашко | Способ лечени зв желудка и двенадцатиперстной кишки |
| SE454480B (sv) | 1986-09-25 | 1988-05-09 | Lars Hammarstrom | Bindningsinducerande komposition |
| SE461313B (sv) | 1988-03-17 | 1990-02-05 | Biora Ab | Bindningsinducerande komposition |
| SE503096C2 (sv) | 1994-09-22 | 1996-03-25 | Biora Ab | Komposition innehållande EDTA för användning vid konditionering av tandrötter |
| WO1997002730A2 (en) | 1995-07-13 | 1997-01-30 | Biora Ab | Enamel matrix related polypeptide |
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- 1999-02-26 RU RU2000124523/15A patent/RU2241489C2/ru active
- 1999-02-26 PL PL382480A patent/PL204797B1/pl unknown
- 1999-02-26 US US09/258,613 patent/US6503539B2/en not_active Expired - Lifetime
- 1999-02-26 JP JP2000533139A patent/JP4726296B2/ja not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2002504520A (ja) | 2002-02-12 |
| US20030064927A1 (en) | 2003-04-03 |
| US20050271604A1 (en) | 2005-12-08 |
| US6503539B2 (en) | 2003-01-07 |
| US6720009B2 (en) | 2004-04-13 |
| US20020169105A1 (en) | 2002-11-14 |
| BRPI9908182C1 (pt) | 2021-05-25 |
| BRPI9908182B8 (pt) | 2018-08-14 |
| US7294352B2 (en) | 2007-11-13 |
| RU2241489C2 (ru) | 2004-12-10 |
| AR020055A1 (es) | 2002-04-10 |
| BRPI9908182B1 (pt) | 2017-09-26 |
| PL204797B1 (pl) | 2010-02-26 |
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