JP4691257B2 - シャペロニン10及びβ−インターフェロンによる多発性硬化症の治療方法 - Google Patents
シャペロニン10及びβ−インターフェロンによる多発性硬化症の治療方法 Download PDFInfo
- Publication number
- JP4691257B2 JP4691257B2 JP2000594486A JP2000594486A JP4691257B2 JP 4691257 B2 JP4691257 B2 JP 4691257B2 JP 2000594486 A JP2000594486 A JP 2000594486A JP 2000594486 A JP2000594486 A JP 2000594486A JP 4691257 B2 JP4691257 B2 JP 4691257B2
- Authority
- JP
- Japan
- Prior art keywords
- cpn10
- ifn
- day
- mice
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Developing Agents For Electrophotography (AREA)
- Surgical Instruments (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU8239 | 1999-01-20 | ||
| AUPP8239 | 1999-01-20 | ||
| AUPP8239A AUPP823999A0 (en) | 1999-01-20 | 1999-01-20 | A treatment |
| PCT/AU2000/000032 WO2000043033A1 (en) | 1999-01-20 | 2000-01-20 | CHAPERONIN 10 AND β-INTERFERON THERAPY OF MULTIPLE SCLEROSIS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002535286A JP2002535286A (ja) | 2002-10-22 |
| JP2002535286A5 JP2002535286A5 (https=) | 2007-02-15 |
| JP4691257B2 true JP4691257B2 (ja) | 2011-06-01 |
Family
ID=3812443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000594486A Expired - Fee Related JP4691257B2 (ja) | 1999-01-20 | 2000-01-20 | シャペロニン10及びβ−インターフェロンによる多発性硬化症の治療方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090214473A1 (https=) |
| EP (1) | EP1150703B1 (https=) |
| JP (1) | JP4691257B2 (https=) |
| KR (1) | KR100694011B1 (https=) |
| AT (1) | ATE313332T1 (https=) |
| AU (2) | AUPP823999A0 (https=) |
| CA (1) | CA2361081C (https=) |
| DE (1) | DE60024967T2 (https=) |
| DK (1) | DK1150703T3 (https=) |
| ES (1) | ES2255484T3 (https=) |
| PT (1) | PT1150703E (https=) |
| WO (1) | WO2000043033A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ548985A (en) * | 2004-01-16 | 2010-02-26 | Cbio Ltd | Chaperonin 10 modulation of toll-like receptor-inducible cytokine and chemokine secretion |
| BG66458B1 (bg) | 2005-03-21 | 2014-10-31 | Иван Иванов | Средство за конкурентно инхибиране на ендогенен гама интерферон |
| EP2457930A1 (en) | 2005-08-31 | 2012-05-30 | CBIO Limited | Modified chaperonin 10 |
| CN101330922A (zh) * | 2005-10-20 | 2008-12-24 | 悉生物有限公司 | 超敏的治疗 |
| CA2644058C (en) * | 2006-03-02 | 2016-08-09 | Cbio Limited | Regulation of immune responses by modulation of the function of antigen presenting cells |
| US9359421B2 (en) | 2008-04-08 | 2016-06-07 | Tigo Gmbh | Suppressor of the endogenous interferon-gamma |
| BG66517B1 (bg) | 2008-04-08 | 2016-02-29 | Tigo Gmbh | Супресор на ендогенния човешки гама - интерферон |
| BG1430U1 (bg) * | 2010-06-25 | 2011-04-29 | Иван ИВАНОВ | Фармацевтично средство |
| BG67190B1 (bg) | 2017-03-29 | 2020-11-16 | Tigo Gmbh | Анти-гама мутантен протеин срещу ендогенния човешки гама интерферон |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995015339A1 (en) * | 1993-11-30 | 1995-06-08 | The University Of Queensland | Antagonists to chaperonin 10 |
| JPH10500109A (ja) * | 1994-05-10 | 1998-01-06 | イミユロジク・フアーマシユーチカル・コーポレーシヨン | 多発性硬化症のための組成物および治療方法 |
| DE19544768C1 (de) * | 1995-11-30 | 1997-07-10 | Rentschler Arzneimittel | Verwendung einer Kombination aus Pentoxifyllin mit Typ-I-Interferonen zur Behandlung der Multiplen Sklerose |
-
1999
- 1999-01-20 AU AUPP8239A patent/AUPP823999A0/en not_active Abandoned
-
2000
- 2000-01-20 CA CA2361081A patent/CA2361081C/en not_active Expired - Fee Related
- 2000-01-20 DE DE60024967T patent/DE60024967T2/de not_active Expired - Lifetime
- 2000-01-20 EP EP00903434A patent/EP1150703B1/en not_active Expired - Lifetime
- 2000-01-20 JP JP2000594486A patent/JP4691257B2/ja not_active Expired - Fee Related
- 2000-01-20 ES ES00903434T patent/ES2255484T3/es not_active Expired - Lifetime
- 2000-01-20 WO PCT/AU2000/000032 patent/WO2000043033A1/en not_active Ceased
- 2000-01-20 AU AU25271/00A patent/AU771867B2/en not_active Ceased
- 2000-01-20 PT PT00903434T patent/PT1150703E/pt unknown
- 2000-01-20 AT AT00903434T patent/ATE313332T1/de not_active IP Right Cessation
- 2000-01-20 DK DK00903434T patent/DK1150703T3/da active
- 2000-01-20 KR KR1020017009163A patent/KR100694011B1/ko not_active Expired - Fee Related
-
2009
- 2009-01-29 US US12/362,456 patent/US20090214473A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020002376A (ko) | 2002-01-09 |
| ATE313332T1 (de) | 2006-01-15 |
| AU2527100A (en) | 2000-08-07 |
| ES2255484T3 (es) | 2006-07-01 |
| CA2361081C (en) | 2010-09-21 |
| EP1150703B1 (en) | 2005-12-21 |
| EP1150703A1 (en) | 2001-11-07 |
| JP2002535286A (ja) | 2002-10-22 |
| KR100694011B1 (ko) | 2007-03-12 |
| CA2361081A1 (en) | 2000-07-27 |
| DE60024967D1 (en) | 2006-01-26 |
| PT1150703E (pt) | 2006-05-31 |
| WO2000043033A1 (en) | 2000-07-27 |
| DK1150703T3 (da) | 2006-05-29 |
| EP1150703A4 (en) | 2004-11-10 |
| DE60024967T2 (de) | 2006-08-17 |
| US20090214473A1 (en) | 2009-08-27 |
| AU771867B2 (en) | 2004-04-01 |
| AUPP823999A0 (en) | 1999-02-11 |
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