JP4669613B2 - 生物学的触媒によるシキミ酸の合成 - Google Patents

生物学的触媒によるシキミ酸の合成 Download PDF

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JP4669613B2
JP4669613B2 JP2000596163A JP2000596163A JP4669613B2 JP 4669613 B2 JP4669613 B2 JP 4669613B2 JP 2000596163 A JP2000596163 A JP 2000596163A JP 2000596163 A JP2000596163 A JP 2000596163A JP 4669613 B2 JP4669613 B2 JP 4669613B2
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acid
shikimic acid
host cell
carbon source
coli
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JP2002535008A (ja
JP2002535008A5 (https=
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フロスト，ジョン，ダブリュー．
フロスト，カレン，エム．
ノップ，デヴィッド，アール．
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ボード オブ トラスティーズ，オブ ミシガン ステイト ユニバーシティ
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03004—3-Dehydroquinate synthase (4.2.3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces

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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2000596163A 1999-01-29 1999-11-04 生物学的触媒によるシキミ酸の合成 Expired - Lifetime JP4669613B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/240,440 US6613552B1 (en) 1999-01-29 1999-01-29 Biocatalytic synthesis of shikimic acid
US09/240,440 1999-01-29
PCT/US1999/026112 WO2000044923A1 (en) 1999-01-29 1999-11-04 Biocatalytic synthesis of shikimic acid

Publications (3)

Publication Number Publication Date
JP2002535008A JP2002535008A (ja) 2002-10-22
JP2002535008A5 JP2002535008A5 (https=) 2010-06-03
JP4669613B2 true JP4669613B2 (ja) 2011-04-13

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JP2000596163A Expired - Lifetime JP4669613B2 (ja) 1999-01-29 1999-11-04 生物学的触媒によるシキミ酸の合成

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US (2) US6613552B1 (https=)
EP (1) EP1151126B1 (https=)
JP (1) JP4669613B2 (https=)
AT (1) ATE514786T1 (https=)
AU (1) AU1342700A (https=)
ES (1) ES2365205T3 (https=)
WO (1) WO2000044923A1 (https=)

Families Citing this family (36)

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US6600077B1 (en) * 1999-01-29 2003-07-29 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of quinic acid and conversion to hydroquinone
WO2002029078A2 (en) * 1999-01-29 2002-04-11 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of shikimic acid
JP2004502457A (ja) * 2000-07-07 2004-01-29 ビーエーエスエフ　アクチェンゲゼルシャフト 除草剤標的としてのデヒドロキナ酸デヒドラターゼ／シキミ酸デヒドロゲナーゼ
DE10107002A1 (de) 2001-02-15 2002-08-29 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von O-Acetyl-L-Serin
US6794164B2 (en) * 2002-01-07 2004-09-21 Novozymes Biopharma Ab Process for the isolation of polyhydroxy cyclic carboxylic acids
US20060121581A1 (en) * 2002-10-04 2006-06-08 Cervin Marguerite A Production of bacterial strains cross reference to related applications
WO2004033646A2 (en) * 2002-10-04 2004-04-22 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
WO2005030949A1 (en) * 2003-09-24 2005-04-07 Board Of Trustees Operating Michigan State University Methods and materials for the production of shikimic acid
ES2626018T3 (es) 2005-06-07 2017-07-21 Dsm Nutritional Products Ag Microorganismos eucariotas para la producción de lípidos y antioxidantes
US20070134282A1 (en) * 2005-12-09 2007-06-14 Stephen F. Austin State University Methods for inhibiting fungal pathogen infestation and propogation
US20070149805A1 (en) * 2005-12-23 2007-06-28 Stephen F. Austin State University Method for the extraction and purification of shikimic acid
US20070161818A1 (en) * 2006-01-06 2007-07-12 Shiyou Li Processes for the extraction and purification of shikimic acid and the products of such processes
US7977077B2 (en) 2006-01-30 2011-07-12 Board Of Trustees Of Michigan State University Synthesis of intermediates of oseltamivir carboxylates
CN101981201A (zh) 2006-08-01 2011-02-23 加拿大海洋营养食品有限公司 产油微生物及改良这些微生物的方法
WO2008027570A2 (en) * 2006-08-30 2008-03-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method of isolating shikimic acid from a plant
US8435769B2 (en) * 2007-04-13 2013-05-07 Monsanto Technology Llc Use of glyphosate to produce shikimic acid in microorganisms
BRPI0818236B1 (pt) * 2007-10-16 2020-07-21 Monsanto Technology Llc processo para recuperação do ácido chiquímico de um fluxo de processo aquoso compreendendo ainda glifosato
US9637746B2 (en) * 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
CN105132387A (zh) * 2008-12-22 2015-12-09 绿光生物科学公司 用于制造化合物的组合物和方法
EP2566953B1 (en) 2010-05-07 2019-01-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
EP2611922A1 (en) 2010-08-31 2013-07-10 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
CN104093848A (zh) 2011-09-09 2014-10-08 绿光生物科学公司 碳青霉烯(carbapenem)的无细胞制备
EP3312267B1 (en) 2012-01-30 2020-03-11 PTT Global Chemical Public Company Limited Production of muconic acid from genetically engineered microorganisms
US10047382B2 (en) 2012-07-03 2018-08-14 Kao Corporation Useful microorganism and method for producing substance of interest
HK1216547A1 (zh) 2012-12-21 2016-11-18 Greenlight Biosciences Inc. 用於將甲烷轉化成燃料、丙酮酸或異丁醇的無細胞系統
US20150247174A1 (en) * 2012-12-28 2015-09-03 Anhui Huaheng Bioengineering Co., Ltd, Engineering bacteria for producing dl-alanine and method for producing dl-alanine by using engineering bacteria
DK2970926T3 (en) 2013-03-13 2018-04-16 Dsm Nutritional Products Ag GENMANIPULATION OF MICROorganisms
AU2014306074B2 (en) 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
KR102105532B1 (ko) * 2013-10-17 2020-04-29 (주)아모레퍼시픽 만능 줄기세포의 유도 방법 및 상기 방법에 의해 제조된 만능줄기세포
US10208313B2 (en) 2014-08-21 2019-02-19 Research Institute Of Innovative Technology For The Earth Coryneform bacterium transformant and process for producing organic compound using the same
BR112017020690A2 (pt) 2015-03-30 2018-06-26 Greenlight Biosciences Inc produção livre de células de ácido ribonucleico
JP7437116B2 (ja) 2016-03-02 2024-02-22 ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド 遺伝子操作された微生物からのムコン酸生成の改善
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KR102894284B1 (ko) 2017-10-11 2025-12-03 그린라이트 바이오사이언시스, 아이엔씨. 뉴클레오시드 트리포스페이트 및 리보핵산 생산을 위한 방법 및 조성물
US20210236444A1 (en) * 2018-08-23 2021-08-05 Sumitomo Bakelite Co., Ltd. Medicinal product, anticancer agent, medicinal intermediate product, and method for producing cyclic carboxylic acid compound or derivative thereof
KR102676309B1 (ko) * 2019-11-22 2024-06-19 (주)에스티알바이오텍 시킴산 생산용 미생물 및 이를 이용한 시킴산 생산 방법

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US5798236A (en) * 1992-09-30 1998-08-25 Genencor International, Inc. Synthesis of quinic acid from glucose
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CA2199853C (en) 1994-09-16 2009-03-24 James C. Liao Microorganisms and methods for overproduction of dahp by cloned pps gene
DE69637492T2 (de) 1995-05-05 2009-06-04 Genencor International, Inc., Palo Alto Anwendung von Glukosetransportmutanten zur Herstellung von Verbindungen des aromatischen Syntheseweges
EP1038968A3 (en) * 1999-03-25 2002-10-02 Ajinomoto Co., Inc. Method for producing shikimic acid

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Publication number Publication date
EP1151126A4 (en) 2002-04-10
WO2000044923A1 (en) 2000-08-03
JP2002535008A (ja) 2002-10-22
AU1342700A (en) 2000-08-18
EP1151126B1 (en) 2011-06-29
US6613552B1 (en) 2003-09-02
ATE514786T1 (de) 2011-07-15
US6472169B1 (en) 2002-10-29
ES2365205T3 (es) 2011-09-26
EP1151126A1 (en) 2001-11-07

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