ATE514786T1 - Biokatalytische synthese von shikiminsäure - Google Patents

Biokatalytische synthese von shikiminsäure

Info

Publication number
ATE514786T1
ATE514786T1 AT99956926T AT99956926T ATE514786T1 AT E514786 T1 ATE514786 T1 AT E514786T1 AT 99956926 T AT99956926 T AT 99956926T AT 99956926 T AT99956926 T AT 99956926T AT E514786 T1 ATE514786 T1 AT E514786T1
Authority
AT
Austria
Prior art keywords
acid
shikiminic
biocatalytic synthesis
synthesis
carbon source
Prior art date
Application number
AT99956926T
Other languages
English (en)
Inventor
John Frost
Karen Frost
David Knop
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan State filed Critical Univ Michigan State
Application granted granted Critical
Publication of ATE514786T1 publication Critical patent/ATE514786T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03004—3-Dehydroquinate synthase (4.2.3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99956926T 1999-01-29 1999-11-04 Biokatalytische synthese von shikiminsäure ATE514786T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/240,440 US6613552B1 (en) 1999-01-29 1999-01-29 Biocatalytic synthesis of shikimic acid
PCT/US1999/026112 WO2000044923A1 (en) 1999-01-29 1999-11-04 Biocatalytic synthesis of shikimic acid

Publications (1)

Publication Number Publication Date
ATE514786T1 true ATE514786T1 (de) 2011-07-15

Family

ID=22906534

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99956926T ATE514786T1 (de) 1999-01-29 1999-11-04 Biokatalytische synthese von shikiminsäure

Country Status (7)

Country Link
US (2) US6613552B1 (de)
EP (1) EP1151126B1 (de)
JP (1) JP4669613B2 (de)
AT (1) ATE514786T1 (de)
AU (1) AU1342700A (de)
ES (1) ES2365205T3 (de)
WO (1) WO2000044923A1 (de)

Families Citing this family (36)

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US6600077B1 (en) * 1999-01-29 2003-07-29 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of quinic acid and conversion to hydroquinone
WO2002029078A2 (en) * 1999-01-29 2002-04-11 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of shikimic acid
WO2002004619A2 (de) * 2000-07-07 2002-01-17 Basf Aktiengesellschaft Dehydroquinat dehydratase/shikimat dehydrogenase als herbizides target
DE10107002A1 (de) 2001-02-15 2002-08-29 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von O-Acetyl-L-Serin
US6794164B2 (en) * 2002-01-07 2004-09-21 Novozymes Biopharma Ab Process for the isolation of polyhydroxy cyclic carboxylic acids
US7371558B2 (en) * 2002-10-04 2008-05-13 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
EP2428573A3 (de) * 2002-10-04 2012-06-27 Genecor International, Inc. Verbesserte Herstellung von Bakterienstämmen sowie Querverweis auf verwandte Anmeldungen
WO2005030949A1 (en) * 2003-09-24 2005-04-07 Board Of Trustees Operating Michigan State University Methods and materials for the production of shikimic acid
DK2447356T3 (en) 2005-06-07 2016-06-06 Dsm Nutritional Products Ag Eukaryotic MICROORGANISMS FOR PRODUCTION OF LIPIDS AND ANTIOXIDANTS
US20070134282A1 (en) * 2005-12-09 2007-06-14 Stephen F. Austin State University Methods for inhibiting fungal pathogen infestation and propogation
US20070149805A1 (en) * 2005-12-23 2007-06-28 Stephen F. Austin State University Method for the extraction and purification of shikimic acid
US20070161818A1 (en) * 2006-01-06 2007-07-12 Shiyou Li Processes for the extraction and purification of shikimic acid and the products of such processes
US7977077B2 (en) 2006-01-30 2011-07-12 Board Of Trustees Of Michigan State University Synthesis of intermediates of oseltamivir carboxylates
WO2008129358A2 (en) 2006-08-01 2008-10-30 Ocean Nutrition Canada Ltd. Oil producing microbes and methods of modification thereof
WO2008027570A2 (en) * 2006-08-30 2008-03-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method of isolating shikimic acid from a plant
WO2008128076A1 (en) * 2007-04-13 2008-10-23 Monsanto Technology Llc Use of glyphosate to produce shikimic acid in microorganisms
ATE541942T1 (de) * 2007-10-16 2012-02-15 Monsanto Technology Llc Verfahren zur rückgewinnung von shikimisäure
WO2010077806A1 (en) * 2008-12-15 2010-07-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
CN105132387A (zh) * 2008-12-22 2015-12-09 绿光生物科学公司 用于制造化合物的组合物和方法
US8956833B2 (en) 2010-05-07 2015-02-17 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
US8916358B2 (en) 2010-08-31 2014-12-23 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
KR20150010932A (ko) 2011-09-09 2015-01-29 그린라이트 바이오사이언시스, 아이엔씨. 카바페넴의 무세포 제조법
BR112014017686A2 (pt) * 2012-01-30 2017-06-27 Myriant Corp produção de ácido mucônico a partir de micro-organismos geneticamente engenheirados
US10047382B2 (en) 2012-07-03 2018-08-14 Kao Corporation Useful microorganism and method for producing substance of interest
SG11201504930PA (en) 2012-12-21 2015-07-30 Greenlight Biosciences Inc Cell-free system for converting methane into fuel, pyruvate or isobutanol
JP2016503650A (ja) * 2012-12-28 2016-02-08 アンホエ ファホン バイオエンジニアリング カンパニー リミテッド Ｄｌ−アラニンを生産する遺伝子操作細菌、及び前記遺伝子操作細菌を用いることによってｄｌ−アラニンを生産する方法
EP2970926B1 (de) 2013-03-13 2018-01-31 DSM Nutritional Products AG Manipulation von mikroorganismen
WO2015021058A2 (en) 2013-08-05 2015-02-12 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
KR102105532B1 (ko) * 2013-10-17 2020-04-29 (주)아모레퍼시픽 만능 줄기세포의 유도 방법 및 상기 방법에 의해 제조된 만능줄기세포
US10208313B2 (en) 2014-08-21 2019-02-19 Research Institute Of Innovative Technology For The Earth Coryneform bacterium transformant and process for producing organic compound using the same
BR112017020690A2 (pt) 2015-03-30 2018-06-26 Greenlight Biosciences Inc produção livre de células de ácido ribonucleico
JP7437116B2 (ja) 2016-03-02 2024-02-22 ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド 遺伝子操作された微生物からのムコン酸生成の改善
SG11201808721YA (en) 2016-04-06 2018-11-29 Greenlight Biosciences Inc Cell-free production of ribonucleic acid
JP7792196B2 (ja) 2017-10-11 2025-12-25 グリーンライト バイオサイエンシーズ インコーポレーテッド ヌクレオシド三リン酸およびリボ核酸の生成のための方法および組成物
EP3842045A4 (de) * 2018-08-23 2021-10-20 Sumitomo Bakelite Co.Ltd. Arzneimittel, antikrebsmittel, medizinisches zwischenprodukt und verfahren zur herstellung einer zyklischen carbonsäureverbindung oder eines derivats davon
KR102676309B1 (ko) * 2019-11-22 2024-06-19 (주)에스티알바이오텍 시킴산 생산용 미생물 및 이를 이용한 시킴산 생산 방법

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US5168056A (en) 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
US5798236A (en) * 1992-09-30 1998-08-25 Genencor International, Inc. Synthesis of quinic acid from glucose
EP0675954B1 (de) 1992-12-21 2002-03-13 Purdue Research Foundation Entsperrung des gemeinsamen syntheseweges von aromatischen aminosäuren
EP0782621B1 (de) 1994-09-16 2006-03-08 THE TEXAS A&M UNIVERSITY SYSTEM Mikroorganismen und Verfahren zur Überproduktion von DAHP mittels klonierten PPSGens
WO1996034961A1 (en) 1995-05-05 1996-11-07 Genencor International, Inc. Application of glucose transport mutants for production of aromatic pathway compounds
EP1038968A3 (de) * 1999-03-25 2002-10-02 Ajinomoto Co., Inc. Verfahren zur Herstellung von Shikimisäure

Also Published As

Publication number Publication date
EP1151126A4 (de) 2002-04-10
US6472169B1 (en) 2002-10-29
JP2002535008A (ja) 2002-10-22
AU1342700A (en) 2000-08-18
US6613552B1 (en) 2003-09-02
WO2000044923A1 (en) 2000-08-03
EP1151126B1 (de) 2011-06-29
JP4669613B2 (ja) 2011-04-13
ES2365205T3 (es) 2011-09-26
EP1151126A1 (de) 2001-11-07

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