ATE514786T1 - Biokatalytische synthese von shikiminsäure - Google Patents

Biokatalytische synthese von shikiminsäure

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Publication number
ATE514786T1
ATE514786T1 AT99956926T AT99956926T ATE514786T1 AT E514786 T1 ATE514786 T1 AT E514786T1 AT 99956926 T AT99956926 T AT 99956926T AT 99956926 T AT99956926 T AT 99956926T AT E514786 T1 ATE514786 T1 AT E514786T1
Authority
AT
Austria
Prior art keywords
acid
shikiminic
biocatalytic synthesis
synthesis
carbon source
Prior art date
Application number
AT99956926T
Other languages
English (en)
Inventor
John Frost
Karen Frost
David Knop
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan State filed Critical Univ Michigan State
Application granted granted Critical
Publication of ATE514786T1 publication Critical patent/ATE514786T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/030043-Dehydroquinate synthase (4.2.3.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/94Saccharomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99956926T 1999-01-29 1999-11-04 Biokatalytische synthese von shikiminsäure ATE514786T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/240,440 US6613552B1 (en) 1999-01-29 1999-01-29 Biocatalytic synthesis of shikimic acid
PCT/US1999/026112 WO2000044923A1 (en) 1999-01-29 1999-11-04 Biocatalytic synthesis of shikimic acid

Publications (1)

Publication Number Publication Date
ATE514786T1 true ATE514786T1 (de) 2011-07-15

Family

ID=22906534

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99956926T ATE514786T1 (de) 1999-01-29 1999-11-04 Biokatalytische synthese von shikiminsäure

Country Status (7)

Country Link
US (2) US6613552B1 (de)
EP (1) EP1151126B1 (de)
JP (1) JP4669613B2 (de)
AT (1) ATE514786T1 (de)
AU (1) AU1342700A (de)
ES (1) ES2365205T3 (de)
WO (1) WO2000044923A1 (de)

Families Citing this family (36)

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US6600077B1 (en) * 1999-01-29 2003-07-29 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of quinic acid and conversion to hydroquinone
WO2002029078A2 (en) * 1999-01-29 2002-04-11 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of shikimic acid
CA2415382A1 (en) * 2000-07-07 2002-01-17 Basf Aktiengesellschaft Dehydroquinate dehydrase/shikimate dehydrogenase as a herbicide target
DE10107002A1 (de) 2001-02-15 2002-08-29 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von O-Acetyl-L-Serin
US6794164B2 (en) * 2002-01-07 2004-09-21 Novozymes Biopharma Ab Process for the isolation of polyhydroxy cyclic carboxylic acids
JP4592418B2 (ja) * 2002-10-04 2010-12-01 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高収率での1,3−プロパンジオールの生物生産のための方法
AU2003277276A1 (en) * 2002-10-04 2004-05-04 Genencor International, Inc. Improved production of bacterial strains cross reference to related applications
US7790431B2 (en) * 2003-09-24 2010-09-07 Board Of Trustees Operating Michigan State University Methods and materials for the production of shikimic acid
CN104745486B (zh) 2005-06-07 2018-01-16 帝斯曼营养品股份公司 生产脂质和抗氧化剂的真核微生物
US20070134282A1 (en) * 2005-12-09 2007-06-14 Stephen F. Austin State University Methods for inhibiting fungal pathogen infestation and propogation
US20070149805A1 (en) * 2005-12-23 2007-06-28 Stephen F. Austin State University Method for the extraction and purification of shikimic acid
US20070161818A1 (en) * 2006-01-06 2007-07-12 Shiyou Li Processes for the extraction and purification of shikimic acid and the products of such processes
US7977077B2 (en) 2006-01-30 2011-07-12 Board Of Trustees Of Michigan State University Synthesis of intermediates of oseltamivir carboxylates
WO2008129358A2 (en) 2006-08-01 2008-10-30 Ocean Nutrition Canada Ltd. Oil producing microbes and methods of modification thereof
WO2008027570A2 (en) * 2006-08-30 2008-03-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method of isolating shikimic acid from a plant
EP2145010A1 (de) * 2007-04-13 2010-01-20 Monsanto Technology, LLC Verwendung von glyphosat zur produktion von shikimsäure in mikroorganismen
WO2009052303A2 (en) * 2007-10-16 2009-04-23 Monsanto Technology Llc Processes for producing and recovering shikimic acid
EP2376619A4 (de) * 2008-12-15 2012-07-04 Greenlight Biosciences Inc Verfahren zur flusssteuerung bei stoffwechselwegen
WO2010074760A1 (en) * 2008-12-22 2010-07-01 Greenlight Biosciences Compositions and methods for the production of a compound
US8956833B2 (en) 2010-05-07 2015-02-17 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
EP2611922A1 (de) 2010-08-31 2013-07-10 Greenlight Biosciences, Inc. Verfahren zur flusssteuerung bei stoffwechselwegen durch proteasemanipulation
SG2014014377A (en) 2011-09-09 2014-05-29 Greenlight Biosciences Inc Cell-free preparation of carbapenems
ES2663445T3 (es) 2012-01-30 2018-04-12 Myriant Corporation Producción de ácido mucónico a partir de microorganismos modificados genéticamente
EP2851421B1 (de) 2012-07-03 2018-11-28 Kao Corporation Nützlicher mikroorganismus und verfahren zur herstellung einer gewünschten substanz
WO2014100722A1 (en) 2012-12-21 2014-06-26 Greenlight Biosciences, Inc. Cell-free system for converting methane into fuel, pyruvate or isobutanol
JP2016503650A (ja) * 2012-12-28 2016-02-08 アンホエ ファホン バイオエンジニアリング カンパニー リミテッド Dl−アラニンを生産する遺伝子操作細菌、及び前記遺伝子操作細菌を用いることによってdl−アラニンを生産する方法
DK2970926T3 (en) 2013-03-13 2018-04-16 Dsm Nutritional Products Ag GENMANIPULATION OF MICROorganisms
CA2919383A1 (en) 2013-08-05 2015-02-12 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
KR102105532B1 (ko) * 2013-10-17 2020-04-29 (주)아모레퍼시픽 만능 줄기세포의 유도 방법 및 상기 방법에 의해 제조된 만능줄기세포
US10208313B2 (en) 2014-08-21 2019-02-19 Research Institute Of Innovative Technology For The Earth Coryneform bacterium transformant and process for producing organic compound using the same
CR20170485A (es) 2015-03-30 2018-02-05 Greenlight Biosciences Inc Producción de ácido ribonucleico libre de células
WO2017151811A1 (en) 2016-03-02 2017-09-08 Myriant Corporation Improved muconic acid production from genetically engineered microorganisms
US10954541B2 (en) 2016-04-06 2021-03-23 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
SG11202003192UA (en) 2017-10-11 2020-05-28 Greenlight Biosciences Inc Methods and compositions for nucleoside triphosphate and ribonucleic acid production
JPWO2020040017A1 (ja) * 2018-08-23 2021-08-10 住友ベークライト株式会社 医薬品、抗がん剤、医薬中間体および環式カルボン酸化合物またはその誘導体の製造方法
KR102676309B1 (ko) * 2019-11-22 2024-06-19 (주)에스티알바이오텍 시킴산 생산용 미생물 및 이를 이용한 시킴산 생산 방법

Family Cites Families (6)

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US5168056A (en) 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
US5798236A (en) * 1992-09-30 1998-08-25 Genencor International, Inc. Synthesis of quinic acid from glucose
DK0675954T3 (da) 1992-12-21 2002-05-27 Genencor Int Afblokering af den fælles syntesevej for aromatiske aminosyrer
WO1996008567A1 (en) 1994-09-16 1996-03-21 Texas A & M University System Microorganisms and methods for overproduction of dahp by cloned pps gene
DK1947186T3 (da) 1995-05-05 2012-02-06 Danisco Us Inc Anvendelse af glucose-transport-mutanter til fremstilling af forbindelser fra den aromatiske pathway
EP1038968A3 (de) * 1999-03-25 2002-10-02 Ajinomoto Co., Inc. Verfahren zur Herstellung von Shikimisäure

Also Published As

Publication number Publication date
AU1342700A (en) 2000-08-18
WO2000044923A1 (en) 2000-08-03
US6472169B1 (en) 2002-10-29
EP1151126A1 (de) 2001-11-07
EP1151126B1 (de) 2011-06-29
JP2002535008A (ja) 2002-10-22
JP4669613B2 (ja) 2011-04-13
ES2365205T3 (es) 2011-09-26
EP1151126A4 (de) 2002-04-10
US6613552B1 (en) 2003-09-02

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