JP4633897B2 - 神経突起伸長剤 - Google Patents

神経突起伸長剤 Download PDF

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Publication number
JP4633897B2
JP4633897B2 JP2000248021A JP2000248021A JP4633897B2 JP 4633897 B2 JP4633897 B2 JP 4633897B2 JP 2000248021 A JP2000248021 A JP 2000248021A JP 2000248021 A JP2000248021 A JP 2000248021A JP 4633897 B2 JP4633897 B2 JP 4633897B2
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JP
Japan
Prior art keywords
cells
test substance
citrus
neurite outgrowth
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2000248021A
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English (en)
Japanese (ja)
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JP2002060340A5 (enExample
JP2002060340A (ja
Inventor
久富 伊藤
真也 田村
寿次 宮崎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagase and Co Ltd
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Nagase and Co Ltd
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Publication date
Application filed by Nagase and Co Ltd filed Critical Nagase and Co Ltd
Priority to JP2000248021A priority Critical patent/JP4633897B2/ja
Priority to US09/927,038 priority patent/US20020040052A1/en
Publication of JP2002060340A publication Critical patent/JP2002060340A/ja
Publication of JP2002060340A5 publication Critical patent/JP2002060340A5/ja
Application granted granted Critical
Publication of JP4633897B2 publication Critical patent/JP4633897B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
JP2000248021A 2000-08-17 2000-08-17 神経突起伸長剤 Expired - Lifetime JP4633897B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2000248021A JP4633897B2 (ja) 2000-08-17 2000-08-17 神経突起伸長剤
US09/927,038 US20020040052A1 (en) 2000-08-17 2001-08-09 Method for neurite outgrowth

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000248021A JP4633897B2 (ja) 2000-08-17 2000-08-17 神経突起伸長剤

Publications (3)

Publication Number Publication Date
JP2002060340A JP2002060340A (ja) 2002-02-26
JP2002060340A5 JP2002060340A5 (enExample) 2007-07-26
JP4633897B2 true JP4633897B2 (ja) 2011-02-16

Family

ID=18738008

Family Applications (1)

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JP2000248021A Expired - Lifetime JP4633897B2 (ja) 2000-08-17 2000-08-17 神経突起伸長剤

Country Status (2)

Country Link
US (1) US20020040052A1 (enExample)
JP (1) JP4633897B2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013099982A1 (ja) 2011-12-26 2013-07-04 森永乳業株式会社 筋萎縮抑制剤

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7146209B2 (en) * 2000-05-08 2006-12-05 Brainsgate, Ltd. Stimulation for treating eye pathologies
JP2006500318A (ja) * 2002-04-25 2006-01-05 ブレインスゲート リミテッド 着臭剤の頭内神経への神経興奮性および／または神経抑制性作用を用いてｂｂｂおよび脳循環の特性を加減する方法および装置
US7684859B2 (en) * 2002-04-25 2010-03-23 Brainsgate Ltd. Stimulation of the OTIC ganglion for treating medical conditions
EP1585430B1 (en) * 2002-11-14 2017-01-11 Brainsgate Ltd. Surgical tools and techniques for stimulation
JP2004284961A (ja) * 2003-03-19 2004-10-14 Okinawa Pref Gov 抗腫瘍成分をサルカケミカンから抽出した製剤、食品または食品添加物
US20070105948A1 (en) * 2003-12-05 2007-05-10 Kazuhito Ikeda Therapeutic or preventive agents for ischemic neuropathy
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US8010189B2 (en) * 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
JP4505555B2 (ja) * 2004-03-02 2010-07-21 康 大泉 神経変性疾患治療剤
US7887851B2 (en) * 2004-06-07 2011-02-15 Kao Corporation Aromatase activator
US20090299418A1 (en) * 2004-08-23 2009-12-03 Brainsgate Ltd. Concurrent bilateral spg modulation
JP5473191B2 (ja) * 2004-11-08 2014-04-16 アークレイ株式会社 ペルオキシソーム増殖剤応答性受容体（ｐｐａｒ）活性化剤、ならびにそれを用いた医薬、サプリメント、機能性食品および食品添加物
JP5563181B2 (ja) * 2005-09-01 2014-07-30 ポッカサッポロフード＆ビバレッジ株式会社 インスリン抵抗性改善剤及び血糖値低下剤
JP2007061028A (ja) * 2005-09-01 2007-03-15 Yasushi Oizumi 学習記憶障害を改善する機能性食品
JP2007302572A (ja) * 2006-05-09 2007-11-22 Pokka Corp 脳機能改善剤及びそれを含有する脳機能改善組成物
JP2007332118A (ja) * 2006-06-19 2007-12-27 Minamide Shoji Kk 神経保護剤
US20090210026A1 (en) * 2006-08-17 2009-08-20 Brainsgate Ltd. Spg stimulation for enhancing neurogenesis and brain metabolism
JP2010518164A (ja) * 2007-02-14 2010-05-27 マース インコーポレーテッド 神経性化合物
JP4921297B2 (ja) * 2007-09-18 2012-04-25 株式会社サウスプロダクト ポリメトキシフラボノイドの抽出方法
US7860569B2 (en) 2007-10-18 2010-12-28 Brainsgate, Ltd. Long-term SPG stimulation therapy for prevention of vascular dementia
EP2112145A1 (en) * 2008-04-24 2009-10-28 AxoGlia Therapeutics S.A. Chromenone derivatives useful for the treatment of neurodegenerative diseases
KR101627001B1 (ko) 2008-06-17 2016-06-03 재팬 로얄 젤리 가부시키가이샤 인지 장해 개선제
WO2010134373A1 (ja) * 2009-05-22 2010-11-25 株式会社エリナ メタボリックシンドロームの予防剤及び／又は治療剤
JP5667358B2 (ja) 2009-06-03 2015-02-12 富士産業株式会社 柑橘類果皮の麹菌発酵組成物
US8481711B2 (en) 2010-07-06 2013-07-09 Hidenori Kamanishi Neurite outgrowth agent
JP6114488B2 (ja) * 2011-05-09 2017-04-12 共栄化学工業株式会社 線維芽細胞増殖因子産生促進剤、血管内皮細胞増殖因子産生促進剤、及び毛髪化粧料
EP2720693B8 (en) 2011-06-17 2017-05-17 Ludwig Aigner Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders
JP5945861B2 (ja) * 2011-09-29 2016-07-05 学校法人松山大学 医薬組成物及びその製造方法
US10548938B2 (en) * 2012-10-12 2020-02-04 University Of The Ryunkyus Method for manufacturing composition containing nobiletin and tangeretin derived from citrus fruits, and composition containing nobiletin and tangeretin obtained thereby
WO2014103410A1 (ja) 2012-12-26 2014-07-03 森永乳業株式会社 Ｉｇｆ－１産生促進剤
EP2878335B1 (en) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant and delivery system for neural stimulator
WO2016072522A1 (ja) * 2014-11-06 2016-05-12 国立大学法人 長崎大学 新規アルツハイマー病治療薬
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
JP6472411B2 (ja) * 2016-06-01 2019-02-20 株式会社三協ホールディングス 医薬組成物および食品
FR3053250B1 (fr) 2016-07-01 2020-11-27 Laboratoires M&L Utilisation d'une huile essentielle d'immortelle pour augmenter ou restaurer la perception tactile cutanee
JP6322755B1 (ja) 2016-08-04 2018-05-09 花王株式会社 ノビレチン含有固体分散体の製造方法
JP6633791B2 (ja) 2018-03-22 2020-01-22 花王株式会社 ノビレチン含有固体分散体の製造方法
CN112402409A (zh) * 2020-12-11 2021-02-26 江汉大学 橘皮素在制备抑制β分泌酶活性药物中的应用
FR3130556A1 (fr) 2021-12-16 2023-06-23 L'oreal Utilisation d’acide salicylique et/ou de ses dérivés et/ou de leurs sels, pour augmenter ou restaurer la perception tactile cutanée

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0578384A (ja) * 1991-03-27 1993-03-30 Taisho Pharmaceut Co Ltd フラボノール誘導体
US6251400B1 (en) * 1997-09-26 2001-06-26 Kgk Synergize Inc Compositions and methods of treatment of neoplastic diseases and hypercholesterolemia with citrus limonoids and flavonoids and tocotrienols
US20010047032A1 (en) * 1999-12-30 2001-11-29 Castillo Gerardo M. Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases
EP1127572A3 (en) * 2000-02-25 2003-05-02 Basf Aktiengesellschaft Use of flavones for treating cycloxygenase-2 mediated diseases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013099982A1 (ja) 2011-12-26 2013-07-04 森永乳業株式会社 筋萎縮抑制剤
KR20140105860A (ko) 2011-12-26 2014-09-02 모리나가 뉴교 가부시키가이샤 근위축 억제제
US9492424B2 (en) 2011-12-26 2016-11-15 Morinaga Milk Industry Co., Ltd. Muscle atrophy inhibitor

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US20020040052A1 (en) 2002-04-04

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