JP4515786B2 - 全血中の分析対象物の計測に対するヘマトクリットの影響を減らす方法ならびに当該方法で有用な試験キット及び試験用品 - Google Patents
全血中の分析対象物の計測に対するヘマトクリットの影響を減らす方法ならびに当該方法で有用な試験キット及び試験用品 Download PDFInfo
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- JP4515786B2 JP4515786B2 JP2004033126A JP2004033126A JP4515786B2 JP 4515786 B2 JP4515786 B2 JP 4515786B2 JP 2004033126 A JP2004033126 A JP 2004033126A JP 2004033126 A JP2004033126 A JP 2004033126A JP 4515786 B2 JP4515786 B2 JP 4515786B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Description
Claims (8)
- 全血サンプル中の分析対象物の存在及び/又は量を測定する方法であって、
(a)分析対象物の定性又は定量のための全血サンプルを用意するステップと、
(b)用意した前記全血サンプルに非溶血性高張性塩組成物を加えることにより赤血球を小さくし、ヘマトクリットの影響を減少させる処理をするステップと、
(c)処理した前記全血サンプルを計測することにより、全血サンプル中の分析対象物の存在及び/又は量を測定するステップと
を含む方法。 - 前記分析対象物が、グルコース、コレステロール、トリグリセリド、エタノール、乳酸、β−ヒドロキシブチレート、ケトン体及びフルクトサミンからなる群より選択される、請求項1記載の方法。
- サンプル中の分析対象物の存在及び/又は量を光学検出法によって測定する、請求項1記載の方法。
- 前記光学検出法が、反射率、吸光度及び透過率からなる群より選択される、請求項3記載の方法。
- 読みが分析対象物及びヘマトクリットの関数である波長で第一の光学計測を実施し、読みが実質的に分析対象物の関数ではない波長で第二の光学計測を実施し、第一の計測の読みを第二の計測の読みにしたがって修正する、請求項3記載の方法。
- サンプル中の分析対象物の存在及び/又は量を電気化学的方法によって測定する、請求項1記載の方法。
- 前記電気化学的方法が、電流滴定法及び電量分析法からなる群より選択される、請求項6記載の方法。
- 前記高張性組成物が、1種以上の有機塩又は1種以上の無機塩もしくはそれらの組み合わせを含む、請求項1記載の方法。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44634003P | 2003-02-11 | 2003-02-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004340923A JP2004340923A (ja) | 2004-12-02 |
JP4515786B2 true JP4515786B2 (ja) | 2010-08-04 |
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Application Number | Title | Priority Date | Filing Date |
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JP2004033126A Expired - Lifetime JP4515786B2 (ja) | 2003-02-11 | 2004-02-10 | 全血中の分析対象物の計測に対するヘマトクリットの影響を減らす方法ならびに当該方法で有用な試験キット及び試験用品 |
Country Status (7)
Country | Link |
---|---|
US (1) | US7323315B2 (ja) |
EP (1) | EP1447665B1 (ja) |
JP (1) | JP4515786B2 (ja) |
CN (1) | CN1558235B (ja) |
AU (1) | AU2004200506B2 (ja) |
CA (1) | CA2457665C (ja) |
HK (1) | HK1070942A1 (ja) |
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US7323315B2 (en) | 2008-01-29 |
AU2004200506B2 (en) | 2008-12-18 |
CN1558235B (zh) | 2010-05-26 |
EP1447665A3 (en) | 2005-12-28 |
US20040157275A1 (en) | 2004-08-12 |
AU2004200506A1 (en) | 2004-08-26 |
CA2457665A1 (en) | 2004-08-11 |
EP1447665B1 (en) | 2016-06-29 |
JP2004340923A (ja) | 2004-12-02 |
EP1447665A2 (en) | 2004-08-18 |
CN1558235A (zh) | 2004-12-29 |
CA2457665C (en) | 2012-12-18 |
HK1070942A1 (en) | 2005-06-30 |
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