JP4426979B2 - 試料注入装置及び試料注入方法及び液体クロマトグラフィ装置 - Google Patents
試料注入装置及び試料注入方法及び液体クロマトグラフィ装置 Download PDFInfo
- Publication number
- JP4426979B2 JP4426979B2 JP2005015583A JP2005015583A JP4426979B2 JP 4426979 B2 JP4426979 B2 JP 4426979B2 JP 2005015583 A JP2005015583 A JP 2005015583A JP 2005015583 A JP2005015583 A JP 2005015583A JP 4426979 B2 JP4426979 B2 JP 4426979B2
- Authority
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- Prior art keywords
- sample
- needle
- mobile phase
- sample injection
- injection port
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002347 injection Methods 0.000 title claims description 214
- 239000007924 injection Substances 0.000 title claims description 214
- 238000000034 method Methods 0.000 title claims description 28
- 238000004811 liquid chromatography Methods 0.000 title claims description 21
- 238000000926 separation method Methods 0.000 claims description 40
- 238000010276 construction Methods 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 description 79
- 241000353790 Doru Species 0.000 description 59
- 239000007788 liquid Substances 0.000 description 56
- 238000005259 measurement Methods 0.000 description 11
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- 230000000052 comparative effect Effects 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 7
- 238000011156 evaluation Methods 0.000 description 7
- 238000003860 storage Methods 0.000 description 5
- 238000001514 detection method Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 3
- 229960003260 chlorhexidine Drugs 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 238000007872 degassing Methods 0.000 description 2
- 239000012046 mixed solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000004506 ultrasonic cleaning Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910020366 ClO 4 Inorganic materials 0.000 description 1
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 235000019169 all-trans-retinol Nutrition 0.000 description 1
- 239000011717 all-trans-retinol Substances 0.000 description 1
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- 238000004891 communication Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
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- 239000002184 metal Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
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- 229920005989 resin Polymers 0.000 description 1
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- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005015583A JP4426979B2 (ja) | 2005-01-24 | 2005-01-24 | 試料注入装置及び試料注入方法及び液体クロマトグラフィ装置 |
| CN2006800030015A CN101107518B (zh) | 2005-01-24 | 2006-01-20 | 试样注入装置和试样注入方法以及液体色谱装置 |
| KR1020077016405A KR101195092B1 (ko) | 2005-01-24 | 2006-01-20 | 시료 주입 장치, 시료 주입 방법 및 액체 크로마토그래피장치 |
| PCT/JP2006/300887 WO2006077985A1 (ja) | 2005-01-24 | 2006-01-20 | 試料注入装置及び試料注入方法及び液体クロマトグラフィ装置 |
| DE602006014089T DE602006014089D1 (de) | 2005-01-24 | 2006-01-20 | Probeninjektor, probeninjektionsverfahren und vorrichtung zur flüssigkeitschromatographie |
| EP06712112A EP1843153B1 (en) | 2005-01-24 | 2006-01-20 | Sample injector, sample injecting method and liquid chromatography device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005015583A JP4426979B2 (ja) | 2005-01-24 | 2005-01-24 | 試料注入装置及び試料注入方法及び液体クロマトグラフィ装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006201121A JP2006201121A (ja) | 2006-08-03 |
| JP2006201121A5 JP2006201121A5 (enExample) | 2007-08-30 |
| JP4426979B2 true JP4426979B2 (ja) | 2010-03-03 |
Family
ID=36692365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005015583A Expired - Fee Related JP4426979B2 (ja) | 2005-01-24 | 2005-01-24 | 試料注入装置及び試料注入方法及び液体クロマトグラフィ装置 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1843153B1 (enExample) |
| JP (1) | JP4426979B2 (enExample) |
| KR (1) | KR101195092B1 (enExample) |
| CN (1) | CN101107518B (enExample) |
| DE (1) | DE602006014089D1 (enExample) |
| WO (1) | WO2006077985A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4887199B2 (ja) * | 2007-04-09 | 2012-02-29 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフィ |
| KR100895981B1 (ko) | 2007-08-06 | 2009-05-07 | 주식회사 휴텍스 | 크로마토그래피를 위한 시료 자동 주입 시스템 및 방법 |
| EP2362214B1 (en) * | 2008-08-01 | 2017-03-01 | Shiseido Company, Ltd. | Sample injection device, sample injection method, and liquid chromatography device |
| CN102171560B (zh) * | 2008-10-03 | 2014-06-04 | 爱科来株式会社 | 分析装置及其控制方法 |
| CN101609072B (zh) * | 2009-07-15 | 2011-09-21 | 武汉市天虹仪表有限责任公司 | 挥发性有机物连续监测仪 |
| JP4933665B1 (ja) | 2011-01-14 | 2012-05-16 | 株式会社 資生堂 | 試料注入装置、試料注入方法、及び液体クロマトグラフィー装置 |
| CN104265952B (zh) * | 2014-10-24 | 2016-08-17 | 北京佰纯润宇生物科技有限公司 | 一种八通阀及一种基于八通阀的层析系统 |
| US20190004016A1 (en) * | 2016-01-26 | 2019-01-03 | Shimadzu Corporation | Chromatograph device |
| WO2019176136A1 (ja) * | 2018-03-14 | 2019-09-19 | 株式会社島津製作所 | 廃液監視装置 |
| CN110455970B (zh) * | 2019-08-20 | 2021-07-23 | 大连依利特分析仪器有限公司 | 进样馏分收集装置及系统 |
| CN116298024A (zh) * | 2023-03-10 | 2023-06-23 | 成都珂睿科技有限公司 | 一种微样品浪费的部分环进样方法及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022065A (en) * | 1976-02-19 | 1977-05-10 | Ramin James A | Calibrated sample delivery apparatus accommodating offset error |
| US4182184A (en) * | 1978-12-14 | 1980-01-08 | Rheodyne Incorporated | Sample injector |
| JPS62176756U (enExample) * | 1986-04-30 | 1987-11-10 | ||
| FR2705582B1 (fr) | 1993-05-25 | 1995-06-30 | Commissariat Energie Atomique | Dispositif automatique de traitement par chromatographie sur colonne et détecteur de liquide utilisable dans un tel dispositif. |
| US6155123A (en) * | 1998-04-17 | 2000-12-05 | Rheodyne, L.P. | Multivalving sample injection system |
| US5993654A (en) * | 1998-09-24 | 1999-11-30 | Eldex Laboratories, Inc. | Pressurized liquid delivery apparatus |
| JP2002228668A (ja) | 2001-01-31 | 2002-08-14 | Shimadzu Corp | オートサンプラ |
| JP2003075419A (ja) * | 2001-09-03 | 2003-03-12 | Shiseido Co Ltd | 液体クロマトグラフィー装置及び試料注入装置及び洗浄装置及び洗浄方法 |
| EP1624301B1 (en) * | 2003-05-15 | 2013-10-30 | Shiseido Company, Ltd. | Sample injection method for liquid chromatography |
-
2005
- 2005-01-24 JP JP2005015583A patent/JP4426979B2/ja not_active Expired - Fee Related
-
2006
- 2006-01-20 CN CN2006800030015A patent/CN101107518B/zh not_active Expired - Fee Related
- 2006-01-20 EP EP06712112A patent/EP1843153B1/en not_active Not-in-force
- 2006-01-20 KR KR1020077016405A patent/KR101195092B1/ko not_active Expired - Fee Related
- 2006-01-20 WO PCT/JP2006/300887 patent/WO2006077985A1/ja not_active Ceased
- 2006-01-20 DE DE602006014089T patent/DE602006014089D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN101107518B (zh) | 2011-11-30 |
| EP1843153A4 (en) | 2009-09-02 |
| KR20070097068A (ko) | 2007-10-02 |
| EP1843153B1 (en) | 2010-05-05 |
| WO2006077985A1 (ja) | 2006-07-27 |
| JP2006201121A (ja) | 2006-08-03 |
| EP1843153A1 (en) | 2007-10-10 |
| KR101195092B1 (ko) | 2012-10-29 |
| CN101107518A (zh) | 2008-01-16 |
| DE602006014089D1 (de) | 2010-06-17 |
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