JP4420143B2 - 高コレステロール血症を治療するためのポリアリルアミンポリマー - Google Patents

高コレステロール血症を治療するためのポリアリルアミンポリマー Download PDF

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JP4420143B2
JP4420143B2 JP50464599A JP50464599A JP4420143B2 JP 4420143 B2 JP4420143 B2 JP 4420143B2 JP 50464599 A JP50464599 A JP 50464599A JP 50464599 A JP50464599 A JP 50464599A JP 4420143 B2 JP4420143 B2 JP 4420143B2
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pharmaceutical composition
composition according
weight
polymer
crosslinking agent
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JP50464599A
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Japanese (ja)
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JP2002516613A5 (https=
JP2002516613A (ja
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ホームズ−ファーレイ，ステファン，ランドル
マンデヴィル，ダブリュ．，ハリー，ザ・サード
バーク，スティーブン，ケイ．
ゴールドバーグ，デニス，アイ．
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ジェンザイム コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
JP50464599A 1997-06-18 1998-06-15 高コレステロール血症を治療するためのポリアリルアミンポリマー Expired - Lifetime JP4420143B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US87842297A 1997-06-18 1997-06-18
US08/878,422 1997-06-18
US92724797A 1997-09-11 1997-09-11
US08/927,247 1997-09-11
US08/979,096 US6423754B1 (en) 1997-06-18 1997-11-26 Method for treating hypercholesterolemia with polyallylamine polymers
US08/979,096 1997-11-26
PCT/US1998/012422 WO1998057652A1 (en) 1997-06-18 1998-06-15 Polyallylamine polymers for treating hypercholesterolemia

Publications (3)

Publication Number Publication Date
JP2002516613A JP2002516613A (ja) 2002-06-04
JP2002516613A5 JP2002516613A5 (https=) 2005-12-08
JP4420143B2 true JP4420143B2 (ja) 2010-02-24

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JP50464599A Expired - Lifetime JP4420143B2 (ja) 1997-06-18 1998-06-15 高コレステロール血症を治療するためのポリアリルアミンポリマー

Country Status (15)

Country Link
US (3) US6423754B1 (https=)
EP (1) EP0996454B1 (https=)
JP (1) JP4420143B2 (https=)
KR (1) KR100567751B1 (https=)
CN (1) CN1211091C (https=)
AT (1) ATE249228T1 (https=)
AU (1) AU735260C (https=)
CA (1) CA2294036C (https=)
DE (1) DE69818058T2 (https=)
IL (1) IL133434A (https=)
MX (1) MXPA99011826A (https=)
MY (1) MY125874A (https=)
NZ (1) NZ501719A (https=)
TW (1) TW526063B (https=)
WO (1) WO1998057652A1 (https=)

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Also Published As

Publication number Publication date
AU735260C (en) 2002-03-28
EP0996454A1 (en) 2000-05-03
CN1211091C (zh) 2005-07-20
KR100567751B1 (ko) 2006-04-05
US20030086898A1 (en) 2003-05-08
IL133434A (en) 2005-09-25
NZ501719A (en) 2001-10-26
CA2294036A1 (en) 1998-12-23
US20060239959A1 (en) 2006-10-26
ATE249228T1 (de) 2003-09-15
DE69818058D1 (de) 2003-10-16
US6423754B1 (en) 2002-07-23
EP0996454B1 (en) 2003-09-10
TW526063B (en) 2003-04-01
IL133434A0 (en) 2001-04-30
JP2002516613A (ja) 2002-06-04
WO1998057652A1 (en) 1998-12-23
DE69818058T2 (de) 2004-07-08
MY125874A (en) 2006-08-30
KR20010013943A (ko) 2001-02-26
CN1263468A (zh) 2000-08-16
HK1029920A1 (en) 2001-04-20
AU7967598A (en) 1999-01-04
CA2294036C (en) 2007-08-21
AU735260B2 (en) 2001-07-05
MXPA99011826A (es) 2002-07-02

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