JP4331398B2 - パルスイオン源及びイオン運動を制動するための輸送デバイスを備えた分析計並びにその使用方法 - Google Patents

パルスイオン源及びイオン運動を制動するための輸送デバイスを備えた分析計並びにその使用方法 Download PDF

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Publication number
JP4331398B2
JP4331398B2 JP2000528992A JP2000528992A JP4331398B2 JP 4331398 B2 JP4331398 B2 JP 4331398B2 JP 2000528992 A JP2000528992 A JP 2000528992A JP 2000528992 A JP2000528992 A JP 2000528992A JP 4331398 B2 JP4331398 B2 JP 4331398B2
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Japan
Prior art keywords
ion
mass spectrometer
ions
mass
spectrometer system
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Expired - Lifetime
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JP2000528992A
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English (en)
Japanese (ja)
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JP2002502084A5 (enExample
JP2002502084A (ja
Inventor
エヌ クラッチンスキー，アンドリュー
ヴィー ロボダ，アレクサンドル
エル スパイサー，ヴィクター
ダブリュ エンズ，エリック
ジー スタンディング，ケネス
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University of Manitoba
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University of Manitoba
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4162020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4331398(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Manitoba filed Critical University of Manitoba
Publication of JP2002502084A publication Critical patent/JP2002502084A/ja
Publication of JP2002502084A5 publication Critical patent/JP2002502084A5/ja
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electron Sources, Ion Sources (AREA)
JP2000528992A 1998-01-23 1999-01-25 パルスイオン源及びイオン運動を制動するための輸送デバイスを備えた分析計並びにその使用方法 Expired - Lifetime JP4331398B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002227806A CA2227806C (en) 1998-01-23 1998-01-23 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
CA2,227,806 1998-01-23
PCT/CA1999/000034 WO1999038185A2 (en) 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use

Publications (3)

Publication Number Publication Date
JP2002502084A JP2002502084A (ja) 2002-01-22
JP2002502084A5 JP2002502084A5 (enExample) 2006-06-08
JP4331398B2 true JP4331398B2 (ja) 2009-09-16

Family

ID=4162020

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000528992A Expired - Lifetime JP4331398B2 (ja) 1998-01-23 1999-01-25 パルスイオン源及びイオン運動を制動するための輸送デバイスを備えた分析計並びにその使用方法

Country Status (8)

Country Link
EP (1) EP1050061B2 (enExample)
JP (1) JP4331398B2 (enExample)
AT (1) ATE273561T2 (enExample)
AU (1) AU745866B2 (enExample)
CA (1) CA2227806C (enExample)
DE (2) DE1050061T1 (enExample)
DK (1) DK1050061T4 (enExample)
WO (1) WO1999038185A2 (enExample)

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* Cited by examiner, † Cited by third party
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US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US6849847B1 (en) 1998-06-12 2005-02-01 Agilent Technologies, Inc. Ambient pressure matrix-assisted laser desorption ionization (MALDI) apparatus and method of analysis
GB9820210D0 (en) 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
EP1181707B8 (en) 1999-06-11 2011-04-27 DH Technologies Development Pte. Ltd. Maldi ion source with a pulse of gas, apparatus and method for determining molecular weight of labile molecules
DE10010204A1 (de) 2000-03-02 2001-09-13 Bruker Daltonik Gmbh Konditionierung eines Ionenstrahls für den Einschuss in ein Flugzeitmassenspektrometer
DE10010902A1 (de) 2000-03-07 2001-09-20 Bruker Daltonik Gmbh Tandem-Massenspektrometer aus zwei Quadrupolfiltern
CA2340150C (en) * 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
GB2364168B (en) * 2000-06-09 2002-06-26 Micromass Ltd Methods and apparatus for mass spectrometry
CA2419866C (en) 2000-11-29 2005-02-01 Micromass Limited Mass spectrometers and methods of mass spectrometry
US6642514B2 (en) 2000-11-29 2003-11-04 Micromass Limited Mass spectrometers and methods of mass spectrometry
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US6617577B2 (en) 2001-04-16 2003-09-09 The Rockefeller University Method and system for mass spectroscopy
EP1430508A1 (en) * 2001-09-17 2004-06-23 MDS Inc., doing business as MDS Sciex Method and apparatus for cooling and focusing ions
AU2002349241A1 (en) * 2001-12-14 2003-06-30 Mds Inc., D.B.A. Mds Sciex Method of chemical of ionization at reduced pressures
AU2003220320A1 (en) 2002-03-21 2003-10-08 Thermo Finnigan Llc Ionization apparatus and method for mass spectrometer system
US7388194B2 (en) 2002-03-28 2008-06-17 Mds Sciex Inc. Method and system for high-throughput quantitation using laser desorption and multiple-reaction-monitoring
US7405397B2 (en) * 2002-03-28 2008-07-29 Mds Sciex Inc. Laser desorption ion source with ion guide coupling for ion mass spectroscopy
AU2003230093A1 (en) * 2002-03-28 2003-10-13 Mds Sciex Method and system for high-throughput quantitation of small molecules using laser desorption and multiple-reaction-monitoring
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
CA2431603C (en) 2003-06-10 2012-03-27 Micromass Uk Limited Mass spectrometer
DE102004025841B4 (de) * 2004-05-24 2015-07-09 Bruker Daltonik Gmbh Verfahren und Vorrichtung zur massenspektroskopischen Untersuchung von Analyten
GB0420408D0 (en) * 2004-09-14 2004-10-20 Micromass Ltd Mass spectrometer
DE102004051785B4 (de) * 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
ES2389111T3 (es) 2005-12-02 2012-10-23 Sirtris Pharmaceuticals, Inc. Ensayos de espectrometría de masas para la actividad acetiltransferasa/desacetilasa
US8097425B2 (en) 2006-03-10 2012-01-17 Tethys Bioscience, Inc. Multiplex protein fractionation
DE102007043456B4 (de) 2007-07-31 2012-02-09 Bruker Daltonik Gmbh Matrixunterstützte Laserdesorption hoher Ionisierungsausbeute
CA3090697A1 (en) * 2018-02-13 2019-08-22 Biomerieux, Inc. Methods for confirming charged-particle generation in an instrument, and related instruments
US12205807B2 (en) 2020-04-01 2025-01-21 Mstm, Llc Multi-mode ionization apparatus and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535235A (en) † 1983-05-06 1985-08-13 Finnigan Corporation Apparatus and method for injection of ions into an ion cyclotron resonance cell
DE3688215T3 (de) † 1985-05-24 2005-08-25 Thermo Finnigan Llc, San Jose Steuerungsverfahren für eine Ionenfalle.
WO1989006044A1 (en) † 1987-12-24 1989-06-29 Unisearch Limited Mass spectrometer
CA1307859C (en) † 1988-12-12 1992-09-22 Donald James Douglas Mass spectrometer and method with improved ion transmission
DE4202123C2 (de) † 1992-01-27 1995-04-06 Bruker Franzen Analytik Gmbh Vorrichtung für die massenspektrometrische Untersuchung schneller organischer Ionen
US5689111A (en) † 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
DE19511333C1 (de) * 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
DE19629134C1 (de) † 1996-07-19 1997-12-11 Bruker Franzen Analytik Gmbh Vorrichtung zur Überführung von Ionen und mit dieser durchgeführtes Meßverfahren
AU1329899A (en) * 1997-12-05 1999-06-28 University Of British Columbia, The Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap

Also Published As

Publication number Publication date
DE69919325T2 (de) 2005-02-17
CA2227806C (en) 2006-07-18
DE69919325T3 (de) 2017-03-02
WO1999038185A2 (en) 1999-07-29
DE69919325D1 (de) 2004-09-16
CA2227806A1 (en) 1999-07-23
EP1050061B1 (en) 2004-08-11
EP1050061B2 (en) 2016-10-19
DE1050061T1 (de) 2001-06-07
JP2002502084A (ja) 2002-01-22
ATE273561T2 (de) 2004-08-15
DK1050061T4 (en) 2017-01-23
AU745866B2 (en) 2002-04-11
WO1999038185A3 (en) 1999-10-21
DK1050061T3 (da) 2004-11-22
EP1050061A2 (en) 2000-11-08
AU2042899A (en) 1999-08-09

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