AU745866B2 - Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use - Google Patents

Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use Download PDF

Info

Publication number
AU745866B2
AU745866B2 AU20428/99A AU2042899A AU745866B2 AU 745866 B2 AU745866 B2 AU 745866B2 AU 20428/99 A AU20428/99 A AU 20428/99A AU 2042899 A AU2042899 A AU 2042899A AU 745866 B2 AU745866 B2 AU 745866B2
Authority
AU
Australia
Prior art keywords
ion
ions
mass spectrometer
mass
ion source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU20428/99A
Other languages
English (en)
Other versions
AU2042899A (en
Inventor
Erich W. Ens
Andrew N. Krutchinsky
Alexandre V. Loboda
Victor L. Spicer
Kenneth G. Standing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manitoba
Original Assignee
University of Manitoba
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4162020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU745866(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Manitoba filed Critical University of Manitoba
Publication of AU2042899A publication Critical patent/AU2042899A/en
Application granted granted Critical
Publication of AU745866B2 publication Critical patent/AU745866B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electron Sources, Ion Sources (AREA)
AU20428/99A 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use Expired AU745866B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002227806A CA2227806C (en) 1998-01-23 1998-01-23 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
CA2227806 1998-01-23
PCT/CA1999/000034 WO1999038185A2 (en) 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use

Publications (2)

Publication Number Publication Date
AU2042899A AU2042899A (en) 1999-08-09
AU745866B2 true AU745866B2 (en) 2002-04-11

Family

ID=4162020

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20428/99A Expired AU745866B2 (en) 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use

Country Status (8)

Country Link
EP (1) EP1050061B2 (enExample)
JP (1) JP4331398B2 (enExample)
AT (1) ATE273561T2 (enExample)
AU (1) AU745866B2 (enExample)
CA (1) CA2227806C (enExample)
DE (2) DE1050061T1 (enExample)
DK (1) DK1050061T4 (enExample)
WO (1) WO1999038185A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US6849847B1 (en) 1998-06-12 2005-02-01 Agilent Technologies, Inc. Ambient pressure matrix-assisted laser desorption ionization (MALDI) apparatus and method of analysis
GB9820210D0 (en) 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
EP1181707B8 (en) 1999-06-11 2011-04-27 DH Technologies Development Pte. Ltd. Maldi ion source with a pulse of gas, apparatus and method for determining molecular weight of labile molecules
DE10010204A1 (de) 2000-03-02 2001-09-13 Bruker Daltonik Gmbh Konditionierung eines Ionenstrahls für den Einschuss in ein Flugzeitmassenspektrometer
DE10010902A1 (de) 2000-03-07 2001-09-20 Bruker Daltonik Gmbh Tandem-Massenspektrometer aus zwei Quadrupolfiltern
CA2340150C (en) * 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
GB2364168B (en) * 2000-06-09 2002-06-26 Micromass Ltd Methods and apparatus for mass spectrometry
CA2419866C (en) 2000-11-29 2005-02-01 Micromass Limited Mass spectrometers and methods of mass spectrometry
US6642514B2 (en) 2000-11-29 2003-11-04 Micromass Limited Mass spectrometers and methods of mass spectrometry
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US6617577B2 (en) 2001-04-16 2003-09-09 The Rockefeller University Method and system for mass spectroscopy
EP1430508A1 (en) * 2001-09-17 2004-06-23 MDS Inc., doing business as MDS Sciex Method and apparatus for cooling and focusing ions
AU2002349241A1 (en) * 2001-12-14 2003-06-30 Mds Inc., D.B.A. Mds Sciex Method of chemical of ionization at reduced pressures
AU2003220320A1 (en) 2002-03-21 2003-10-08 Thermo Finnigan Llc Ionization apparatus and method for mass spectrometer system
US7388194B2 (en) 2002-03-28 2008-06-17 Mds Sciex Inc. Method and system for high-throughput quantitation using laser desorption and multiple-reaction-monitoring
US7405397B2 (en) * 2002-03-28 2008-07-29 Mds Sciex Inc. Laser desorption ion source with ion guide coupling for ion mass spectroscopy
AU2003230093A1 (en) * 2002-03-28 2003-10-13 Mds Sciex Method and system for high-throughput quantitation of small molecules using laser desorption and multiple-reaction-monitoring
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
CA2431603C (en) 2003-06-10 2012-03-27 Micromass Uk Limited Mass spectrometer
DE102004025841B4 (de) * 2004-05-24 2015-07-09 Bruker Daltonik Gmbh Verfahren und Vorrichtung zur massenspektroskopischen Untersuchung von Analyten
GB0420408D0 (en) * 2004-09-14 2004-10-20 Micromass Ltd Mass spectrometer
DE102004051785B4 (de) * 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
ES2389111T3 (es) 2005-12-02 2012-10-23 Sirtris Pharmaceuticals, Inc. Ensayos de espectrometría de masas para la actividad acetiltransferasa/desacetilasa
US8097425B2 (en) 2006-03-10 2012-01-17 Tethys Bioscience, Inc. Multiplex protein fractionation
DE102007043456B4 (de) 2007-07-31 2012-02-09 Bruker Daltonik Gmbh Matrixunterstützte Laserdesorption hoher Ionisierungsausbeute
CA3090697A1 (en) * 2018-02-13 2019-08-22 Biomerieux, Inc. Methods for confirming charged-particle generation in an instrument, and related instruments
US12205807B2 (en) 2020-04-01 2025-01-21 Mstm, Llc Multi-mode ionization apparatus and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5689111A (en) * 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
WO1999030350A1 (en) * 1997-12-05 1999-06-17 University Of British Columbia Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535235A (en) † 1983-05-06 1985-08-13 Finnigan Corporation Apparatus and method for injection of ions into an ion cyclotron resonance cell
DE3688215T3 (de) † 1985-05-24 2005-08-25 Thermo Finnigan Llc, San Jose Steuerungsverfahren für eine Ionenfalle.
WO1989006044A1 (en) † 1987-12-24 1989-06-29 Unisearch Limited Mass spectrometer
CA1307859C (en) † 1988-12-12 1992-09-22 Donald James Douglas Mass spectrometer and method with improved ion transmission
DE4202123C2 (de) † 1992-01-27 1995-04-06 Bruker Franzen Analytik Gmbh Vorrichtung für die massenspektrometrische Untersuchung schneller organischer Ionen
DE19511333C1 (de) * 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
DE19629134C1 (de) † 1996-07-19 1997-12-11 Bruker Franzen Analytik Gmbh Vorrichtung zur Überführung von Ionen und mit dieser durchgeführtes Meßverfahren

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5689111A (en) * 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
WO1999030350A1 (en) * 1997-12-05 1999-06-17 University Of British Columbia Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap

Also Published As

Publication number Publication date
JP4331398B2 (ja) 2009-09-16
DE69919325T2 (de) 2005-02-17
CA2227806C (en) 2006-07-18
DE69919325T3 (de) 2017-03-02
WO1999038185A2 (en) 1999-07-29
DE69919325D1 (de) 2004-09-16
CA2227806A1 (en) 1999-07-23
EP1050061B1 (en) 2004-08-11
EP1050061B2 (en) 2016-10-19
DE1050061T1 (de) 2001-06-07
JP2002502084A (ja) 2002-01-22
ATE273561T2 (de) 2004-08-15
DK1050061T4 (en) 2017-01-23
WO1999038185A3 (en) 1999-10-21
DK1050061T3 (da) 2004-11-22
EP1050061A2 (en) 2000-11-08
AU2042899A (en) 1999-08-09

Similar Documents

Publication Publication Date Title
US6331702B1 (en) Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
AU745866B2 (en) Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
EP1135790B1 (en) Method and apparatus for multiple stages of mass spectrometry
US6670606B2 (en) Preparation of ion pulse for time-of-flight and for tandem time-of-flight mass analysis
Krutchinsky et al. Orthogonal injection of matrix‐assisted laser desorption/ionization ions into a time‐of‐flight spectrometer through a collisional damping interface
US7385187B2 (en) Multi-reflecting time-of-flight mass spectrometer and method of use
US6534764B1 (en) Tandem time-of-flight mass spectrometer with damping in collision cell and method for use
CN1853255B (zh) 多反射飞行时间质谱仪及使用方法
CA2626383C (en) Mass spectrometry with multipole ion guides
US6906324B1 (en) Apparatus and method for analyzing samples in a dual ion trap mass spectrometer
US6872941B1 (en) Charged particle trapping in near-surface potential wells
US7109479B2 (en) Method and system for mass spectroscopy
CA2318855C (en) Mass spectrometry with multipole ion guide
GB2361580A (en) Time of flight mass analyser with selectable drift length
Ens et al. Hybrid quadrupole/time‐of‐flight mass spectrometers for analysis of biomolecules
GB2414855A (en) Ion fragmentation by electron capture
USRE39099E1 (en) Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
Chernushevich et al. ANALYTICAL

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired