ATE273561T2 - Spektrometer mit gepulster ionenquelle, kopplungsvorrichtung zur dämpfung der ionenbewegung, und methode zur verwendung derselben - Google Patents

Spektrometer mit gepulster ionenquelle, kopplungsvorrichtung zur dämpfung der ionenbewegung, und methode zur verwendung derselben Download PDF

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Publication number
ATE273561T2
ATE273561T2 AT99900849T AT99900849T ATE273561T2 AT E273561 T2 ATE273561 T2 AT E273561T2 AT 99900849 T AT99900849 T AT 99900849T AT 99900849 T AT99900849 T AT 99900849T AT E273561 T2 ATE273561 T2 AT E273561T2
Authority
AT
Austria
Prior art keywords
ion
ions
source
spectrometer
transmission device
Prior art date
Application number
AT99900849T
Other languages
German (de)
English (en)
Inventor
Andrew N Krutchinsky
Alexandre V Loboda
Victor L Spicer
Erich W Ens
Kenneth G Standing
Original Assignee
Univ Manitoba
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4162020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE273561(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Manitoba filed Critical Univ Manitoba
Application granted granted Critical
Publication of ATE273561T2 publication Critical patent/ATE273561T2/de

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Electron Sources, Ion Sources (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT99900849T 1998-01-23 1999-01-25 Spektrometer mit gepulster ionenquelle, kopplungsvorrichtung zur dämpfung der ionenbewegung, und methode zur verwendung derselben ATE273561T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002227806A CA2227806C (en) 1998-01-23 1998-01-23 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
PCT/CA1999/000034 WO1999038185A2 (en) 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use

Publications (1)

Publication Number Publication Date
ATE273561T2 true ATE273561T2 (de) 2004-08-15

Family

ID=4162020

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99900849T ATE273561T2 (de) 1998-01-23 1999-01-25 Spektrometer mit gepulster ionenquelle, kopplungsvorrichtung zur dämpfung der ionenbewegung, und methode zur verwendung derselben

Country Status (8)

Country Link
EP (1) EP1050061B2 (enExample)
JP (1) JP4331398B2 (enExample)
AT (1) ATE273561T2 (enExample)
AU (1) AU745866B2 (enExample)
CA (1) CA2227806C (enExample)
DE (2) DE1050061T1 (enExample)
DK (1) DK1050061T4 (enExample)
WO (1) WO1999038185A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US6849847B1 (en) 1998-06-12 2005-02-01 Agilent Technologies, Inc. Ambient pressure matrix-assisted laser desorption ionization (MALDI) apparatus and method of analysis
GB9820210D0 (en) * 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
DE60044899D1 (de) 1999-06-11 2010-10-14 Applied Biosystems Llc Maldi ionenquelle mit gasimpuls, vorrichtung und verfahren zur ermittlung des molekulargewichtes labilen moleküle
DE10010204A1 (de) 2000-03-02 2001-09-13 Bruker Daltonik Gmbh Konditionierung eines Ionenstrahls für den Einschuss in ein Flugzeitmassenspektrometer
DE10010902A1 (de) 2000-03-07 2001-09-20 Bruker Daltonik Gmbh Tandem-Massenspektrometer aus zwei Quadrupolfiltern
US6586727B2 (en) * 2000-06-09 2003-07-01 Micromass Limited Methods and apparatus for mass spectrometry
CA2340150C (en) * 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
US6642514B2 (en) 2000-11-29 2003-11-04 Micromass Limited Mass spectrometers and methods of mass spectrometry
GB2370686B (en) 2000-11-29 2003-10-22 Micromass Ltd Mass spectrometers and methods of mass spectrometry
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US6617577B2 (en) 2001-04-16 2003-09-09 The Rockefeller University Method and system for mass spectroscopy
EP1430508A1 (en) * 2001-09-17 2004-06-23 MDS Inc., doing business as MDS Sciex Method and apparatus for cooling and focusing ions
WO2003052399A2 (en) * 2001-12-14 2003-06-26 Mds Inc., D.B.A. Mds Sciex Method of chemical of ionization at reduced pressures
CA2479872C (en) 2002-03-21 2009-06-23 Thermo Finnigan Llc Ionization apparatus and method for mass spectrometer system
CA2477835C (en) * 2002-03-28 2011-11-22 Mds Sciex Method and system for high-throughput quantitation of small molecules using laser desorption and multiple-reaction-monitoring
US7388194B2 (en) 2002-03-28 2008-06-17 Mds Sciex Inc. Method and system for high-throughput quantitation using laser desorption and multiple-reaction-monitoring
US7405397B2 (en) 2002-03-28 2008-07-29 Mds Sciex Inc. Laser desorption ion source with ion guide coupling for ion mass spectroscopy
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
US6977371B2 (en) 2003-06-10 2005-12-20 Micromass Uk Limited Mass spectrometer
DE102004025841B4 (de) * 2004-05-24 2015-07-09 Bruker Daltonik Gmbh Verfahren und Vorrichtung zur massenspektroskopischen Untersuchung von Analyten
GB0420408D0 (en) * 2004-09-14 2004-10-20 Micromass Ltd Mass spectrometer
DE102004051785B4 (de) * 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
EP1955077B1 (en) 2005-12-02 2012-06-13 Sirtris Pharmaceuticals, Inc. Mass spectrometry assays for acetyltransferase/deacetylase activity
WO2008076139A1 (en) 2006-03-10 2008-06-26 Tethys Bioscience, Inc. Multiplex protein fractionation
DE102007043456B4 (de) 2007-07-31 2012-02-09 Bruker Daltonik Gmbh Matrixunterstützte Laserdesorption hoher Ionisierungsausbeute
KR102744729B1 (ko) * 2018-02-13 2024-12-18 바이오메리욱스, 인코포레이티드. 기기에서 하전 입자 생성을 확인하기 위한 방법들 및 관련 기기들
US12205807B2 (en) 2020-04-01 2025-01-21 Mstm, Llc Multi-mode ionization apparatus and uses thereof
CN114729014A (zh) 2020-04-08 2022-07-08 纳诺皮技术有限公司 单克隆抗体及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535235A (en) † 1983-05-06 1985-08-13 Finnigan Corporation Apparatus and method for injection of ions into an ion cyclotron resonance cell
EP0409362B1 (en) † 1985-05-24 1995-04-19 Finnigan Corporation Method of operating an ion trap
JPH03503815A (ja) † 1987-12-24 1991-08-22 ユニサーチ　リミテッド 質量分析計
CA1307859C (en) † 1988-12-12 1992-09-22 Donald James Douglas Mass spectrometer and method with improved ion transmission
DE4202123C2 (de) † 1992-01-27 1995-04-06 Bruker Franzen Analytik Gmbh Vorrichtung für die massenspektrometrische Untersuchung schneller organischer Ionen
US5689111A (en) † 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
DE19511333C1 (de) * 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
DE19629134C1 (de) † 1996-07-19 1997-12-11 Bruker Franzen Analytik Gmbh Vorrichtung zur Überführung von Ionen und mit dieser durchgeführtes Meßverfahren
DE69806415T2 (de) * 1997-12-05 2003-02-20 The University Of British Columbia, Vancouver Verfahren zur untersuchung von ionen in einem apparat mit einem flugzeit-spektrometer und einer linearen quadrupol-ionenfalle

Also Published As

Publication number Publication date
DK1050061T3 (da) 2004-11-22
JP2002502084A (ja) 2002-01-22
DE69919325D1 (de) 2004-09-16
WO1999038185A3 (en) 1999-10-21
AU745866B2 (en) 2002-04-11
DE1050061T1 (de) 2001-06-07
DE69919325T2 (de) 2005-02-17
WO1999038185A2 (en) 1999-07-29
CA2227806C (en) 2006-07-18
EP1050061B2 (en) 2016-10-19
AU2042899A (en) 1999-08-09
EP1050061B1 (en) 2004-08-11
DE69919325T3 (de) 2017-03-02
DK1050061T4 (en) 2017-01-23
JP4331398B2 (ja) 2009-09-16
EP1050061A2 (en) 2000-11-08
CA2227806A1 (en) 1999-07-23

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