JP4324636B2 - １６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子 - Google Patents

１６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子 Download PDF

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JP4324636B2
JP4324636B2 JP2008504501A JP2008504501A JP4324636B2 JP 4324636 B2 JP4324636 B2 JP 4324636B2 JP 2008504501 A JP2008504501 A JP 2008504501A JP 2008504501 A JP2008504501 A JP 2008504501A JP 4324636 B2 JP4324636 B2 JP 4324636B2
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161p2f10b
antibody
protein
cancer
cells
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JP2008538182A (ja
JP2008538182A5 (enExample
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アヤ ヤコボビッツ，
スティーブン ビー． カナー，
ピア エム． シャリタ−エイド，
ジュアン ジェイ． ペレス−ビラール，
ダウレット サトパーエフ，
アーサー ビー． ライタノ，
ロバート ケンドール モリソン，
カレン ジェーン マイリック モリソン，
シャオ−チ チア，
ジーン グダス，
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アジェンシス，インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2008504501A 2005-03-31 2006-03-31 １６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子 Expired - Lifetime JP4324636B2 (ja)

Applications Claiming Priority (3)

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US66758805P 2005-03-31 2005-03-31
US70097505P 2005-07-20 2005-07-20
PCT/US2006/012314 WO2006105488A2 (en) 2005-03-31 2006-03-31 Antibodies and related molecules that bind to 161p2f10b proteins

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JP2009074057A Division JP2009171982A (ja) 2005-03-31 2009-03-25 １６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子

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JP2008538182A JP2008538182A (ja) 2008-10-16
JP2008538182A5 JP2008538182A5 (enExample) 2009-06-25
JP4324636B2 true JP4324636B2 (ja) 2009-09-02

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JP2009074057A Pending JP2009171982A (ja) 2005-03-31 2009-03-25 １６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子
JP2012009690A Expired - Lifetime JP5480921B2 (ja) 2005-03-31 2012-01-20 １６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子

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JP2012009690A Expired - Lifetime JP5480921B2 (ja) 2005-03-31 2012-01-20 １６１ｐ２ｆ１０ｂタンパク質に結合する抗体および関連分子

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US (3) US20090022663A1 (enExample)
EP (3) EP3300739A3 (enExample)
JP (3) JP4324636B2 (enExample)
KR (1) KR20080003390A (enExample)
AU (1) AU2006230563B8 (enExample)
BR (1) BRPI0609655A2 (enExample)
CA (1) CA2603093A1 (enExample)
HK (1) HK1253391A1 (enExample)
IL (1) IL186385A0 (enExample)
NO (1) NO20075103L (enExample)
NZ (1) NZ562453A (enExample)
RU (1) RU2413735C2 (enExample)
WO (1) WO2006105488A2 (enExample)

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EP1537140B1 (en) 2001-11-07 2013-01-02 Agensys, Inc. Nucleic acid and corresponding protein entitled 161p2f10b useful in treatment and detection of cancer
EP3300739A3 (en) * 2005-03-31 2018-07-18 Agensys, Inc. Antibodies and related molecules that bind to 161p2f10b proteins
US8350009B2 (en) * 2005-03-31 2013-01-08 Agensys, Inc. Antibodies and related molecules that bind to 161P2F10B proteins
WO2008029807A1 (fr) * 2006-09-06 2008-03-13 Japan Science And Technology Agency Nouveau polypeptide ayant une cytotoxicité contre le cancer, procédé pour cribler le polypeptide et utilisation du polypeptide
BR112012019780A2 (pt) * 2010-02-08 2020-09-01 Agensys, Inc. conjugados de fármaco e anticorpo (adc) que ligam a proteínas 161p2f10b
WO2011116011A2 (en) * 2010-03-15 2011-09-22 Klatu Networks Systems and methods for monitoring, inferring state of health, and optimizing efficiency of refrigeration systems
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EA202191201A1 (ru) 2018-12-03 2022-01-26 Эдженсис, Инк. Фармацевтические композиции, включающие конъюгаты анти-191p4d12 антитело-лекарственное средство, и способы их применения
EP3930850A1 (en) * 2019-03-01 2022-01-05 Xencor, Inc. Heterodimeric antibodies that bind enpp3 and cd3
WO2020247054A1 (en) 2019-06-05 2020-12-10 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
WO2022182415A1 (en) 2021-02-24 2022-09-01 Massachusetts Institute Of Technology Himastatin derivatives, and processes of preparation thereof, and uses thereof
WO2023236099A1 (en) * 2022-06-08 2023-12-14 Zhejiang Shimai Pharmaceutical Co., Ltd. Antibodies against enpp3 and uses thereof

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BRPI0609655A2 (pt) 2010-03-16
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IL186385A0 (en) 2011-08-01
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AU2006230563B2 (en) 2010-06-03
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