JP4295386B2 - 高活性アルカリ性ホスファターゼ - Google Patents

高活性アルカリ性ホスファターゼ Download PDF

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Publication number
JP4295386B2
JP4295386B2 JP12649499A JP12649499A JP4295386B2 JP 4295386 B2 JP4295386 B2 JP 4295386B2 JP 12649499 A JP12649499 A JP 12649499A JP 12649499 A JP12649499 A JP 12649499A JP 4295386 B2 JP4295386 B2 JP 4295386B2
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Japan
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biap
seq
cdna
biapi
iii
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JP12649499A
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English (en)
Japanese (ja)
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JPH11332586A5 (enExample
JPH11332586A (ja
Inventor
ホエルク ヴェルナー
ミューラー レイナー
ブルトシャー ヘルムット
ルイス ミラン ホセ
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ロシュ ダイアグノスティックス ゲーエムベーハー
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Publication of JPH11332586A publication Critical patent/JPH11332586A/ja
Publication of JPH11332586A5 publication Critical patent/JPH11332586A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
JP12649499A 1998-05-05 1999-05-06 高活性アルカリ性ホスファターゼ Expired - Lifetime JP4295386B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19819962:7 1998-05-05
DE19819962A DE19819962A1 (de) 1998-05-05 1998-05-05 Hochaktive alkalische Phosphatase

Publications (3)

Publication Number Publication Date
JPH11332586A JPH11332586A (ja) 1999-12-07
JPH11332586A5 JPH11332586A5 (enExample) 2006-06-15
JP4295386B2 true JP4295386B2 (ja) 2009-07-15

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ID=7866683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12649499A Expired - Lifetime JP4295386B2 (ja) 1998-05-05 1999-05-06 高活性アルカリ性ホスファターゼ

Country Status (8)

Country Link
US (1) US6406899B1 (enExample)
EP (1) EP0955369B1 (enExample)
JP (1) JP4295386B2 (enExample)
AT (1) ATE323769T1 (enExample)
AU (1) AU765392B2 (enExample)
DE (2) DE19819962A1 (enExample)
NZ (1) NZ335500A (enExample)
ZA (1) ZA993079B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11932860B2 (en) 2017-10-03 2024-03-19 Kikkoman Corporation Method for producing alkaline phosphatase, alkaline phosphatase obtained using said method, and vector and transformant for production thereof

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10036491A1 (de) * 2000-07-25 2002-02-07 Roche Diagnostics Gmbh Expression von Alkalischer Phosphatase in Hefe
DE10213201A1 (de) 2002-03-25 2003-10-16 Roche Diagnostics Gmbh Erzeugung von schwach aktiven oder inaktiven Mutanten von Alkalischer Phosphatase und deren Expression in Hefe
EP1460425A1 (en) 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
US20110142817A1 (en) * 2004-02-04 2011-06-16 Pharmaaware Sepsis B.V. Means and method for treating and/or preventing necrotizing enterocolitis
WO2005074978A1 (en) * 2004-02-04 2005-08-18 Pharmaaware Sepsis B.V. Use of alkaline phosphatase for the detoxification of lps present at mucosal barriers
HUE051470T2 (hu) 2014-01-24 2021-03-01 Am Pharma Bv Egy alkalikus foszfatáz feldolgozási folyamata
AU2015209783B2 (en) 2014-01-24 2020-10-01 Am-Pharma B.V. Chimeric alkaline phosphatase-like proteins
JP6977301B2 (ja) * 2016-04-13 2021-12-08 東ソー株式会社 変異型アルカリホスファターゼをコードする遺伝子
US11338020B2 (en) 2018-01-09 2022-05-24 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of neurodevelopmental disorders
US11654184B2 (en) 2018-03-20 2023-05-23 Theriva Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
WO2019183208A1 (en) 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Intestinal alkaline phosphatase formulations
US11999978B2 (en) 2018-09-25 2024-06-04 Toray Industries, Inc. Alkaline phosphatase composition, method of producing dephosphorylated nucleic acid and method of producing labeled nucleic acid
EP3965805A4 (en) 2019-05-06 2023-01-25 Synthetic Biologics, Inc. ALKALINE PHOSPHATE BASED ONCOLOGICAL TREATMENTS
JP7510787B2 (ja) * 2020-05-28 2024-07-04 シスメックス株式会社 アルカリフォスファターゼ融合抗体及びその製造方法、並びに免疫測定用試薬及び免疫測定方法
JP2024046503A (ja) 2022-09-22 2024-04-03 シスメックス株式会社 細胞外小胞に含まれるアルカリフォスファターゼの活性を測定する方法、キャリブレータ及び結合体
JP2025144440A (ja) 2024-03-19 2025-10-02 シスメックス株式会社 試料中の細胞外小胞に含まれるアルカリホスファターゼの活性又は濃度を測定する方法、ポリペプチド分子及びその製造方法、並びにキャリブレータ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328918D0 (en) * 1983-10-28 1983-11-30 Unilever Plc Alkaline phosphatase
ATE175998T1 (de) * 1992-03-10 1999-02-15 Jolla Cancer Res Found Rekombinierte alkalische phosphatase aus kälberdarm

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11932860B2 (en) 2017-10-03 2024-03-19 Kikkoman Corporation Method for producing alkaline phosphatase, alkaline phosphatase obtained using said method, and vector and transformant for production thereof

Also Published As

Publication number Publication date
US6406899B1 (en) 2002-06-18
AU2692699A (en) 1999-11-11
DE19819962A1 (de) 1999-11-11
ZA993079B (en) 2000-11-06
EP0955369A3 (de) 2002-02-06
EP0955369B1 (de) 2006-04-19
DE59913343D1 (de) 2006-05-24
AU765392B2 (en) 2003-09-18
ATE323769T1 (de) 2006-05-15
EP0955369A2 (de) 1999-11-10
NZ335500A (en) 2000-02-28
JPH11332586A (ja) 1999-12-07

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