AU765392B2 - Highly active alkaline phosphatase - Google Patents

Highly active alkaline phosphatase Download PDF

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Publication number
AU765392B2
AU765392B2 AU26926/99A AU2692699A AU765392B2 AU 765392 B2 AU765392 B2 AU 765392B2 AU 26926/99 A AU26926/99 A AU 26926/99A AU 2692699 A AU2692699 A AU 2692699A AU 765392 B2 AU765392 B2 AU 765392B2
Authority
AU
Australia
Prior art keywords
seq
biap
ala
gly
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU26926/99A
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English (en)
Other versions
AU2692699A (en
Inventor
Helmut Burtscher
Werner Hoelke
Jose Luis Millan
Rainer Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of AU2692699A publication Critical patent/AU2692699A/en
Application granted granted Critical
Publication of AU765392B2 publication Critical patent/AU765392B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
AU26926/99A 1998-05-05 1999-05-04 Highly active alkaline phosphatase Ceased AU765392B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19819962A DE19819962A1 (de) 1998-05-05 1998-05-05 Hochaktive alkalische Phosphatase
DE19819962 1998-05-05

Publications (2)

Publication Number Publication Date
AU2692699A AU2692699A (en) 1999-11-11
AU765392B2 true AU765392B2 (en) 2003-09-18

Family

ID=7866683

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26926/99A Ceased AU765392B2 (en) 1998-05-05 1999-05-04 Highly active alkaline phosphatase

Country Status (8)

Country Link
US (1) US6406899B1 (enExample)
EP (1) EP0955369B1 (enExample)
JP (1) JP4295386B2 (enExample)
AT (1) ATE323769T1 (enExample)
AU (1) AU765392B2 (enExample)
DE (2) DE19819962A1 (enExample)
NZ (1) NZ335500A (enExample)
ZA (1) ZA993079B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10036491A1 (de) * 2000-07-25 2002-02-07 Roche Diagnostics Gmbh Expression von Alkalischer Phosphatase in Hefe
DE10213201A1 (de) 2002-03-25 2003-10-16 Roche Diagnostics Gmbh Erzeugung von schwach aktiven oder inaktiven Mutanten von Alkalischer Phosphatase und deren Expression in Hefe
EP1460425A1 (en) 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
US20110142817A1 (en) * 2004-02-04 2011-06-16 Pharmaaware Sepsis B.V. Means and method for treating and/or preventing necrotizing enterocolitis
WO2005074978A1 (en) * 2004-02-04 2005-08-18 Pharmaaware Sepsis B.V. Use of alkaline phosphatase for the detoxification of lps present at mucosal barriers
HUE051470T2 (hu) 2014-01-24 2021-03-01 Am Pharma Bv Egy alkalikus foszfatáz feldolgozási folyamata
AU2015209783B2 (en) 2014-01-24 2020-10-01 Am-Pharma B.V. Chimeric alkaline phosphatase-like proteins
JP6977301B2 (ja) * 2016-04-13 2021-12-08 東ソー株式会社 変異型アルカリホスファターゼをコードする遺伝子
JP7692683B2 (ja) * 2017-10-03 2025-06-16 キッコーマン株式会社 アルカリホスファターゼの製造方法及びそれを用いて得られるアルカリホスファターゼ、並びにその製造のためのベクター及び形質転換体
US11338020B2 (en) 2018-01-09 2022-05-24 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of neurodevelopmental disorders
US11654184B2 (en) 2018-03-20 2023-05-23 Theriva Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
WO2019183208A1 (en) 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Intestinal alkaline phosphatase formulations
US11999978B2 (en) 2018-09-25 2024-06-04 Toray Industries, Inc. Alkaline phosphatase composition, method of producing dephosphorylated nucleic acid and method of producing labeled nucleic acid
EP3965805A4 (en) 2019-05-06 2023-01-25 Synthetic Biologics, Inc. ALKALINE PHOSPHATE BASED ONCOLOGICAL TREATMENTS
JP7510787B2 (ja) * 2020-05-28 2024-07-04 シスメックス株式会社 アルカリフォスファターゼ融合抗体及びその製造方法、並びに免疫測定用試薬及び免疫測定方法
JP2024046503A (ja) 2022-09-22 2024-04-03 シスメックス株式会社 細胞外小胞に含まれるアルカリフォスファターゼの活性を測定する方法、キャリブレータ及び結合体
JP2025144440A (ja) 2024-03-19 2025-10-02 シスメックス株式会社 試料中の細胞外小胞に含まれるアルカリホスファターゼの活性又は濃度を測定する方法、ポリペプチド分子及びその製造方法、並びにキャリブレータ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328918D0 (en) * 1983-10-28 1983-11-30 Unilever Plc Alkaline phosphatase
ATE175998T1 (de) * 1992-03-10 1999-02-15 Jolla Cancer Res Found Rekombinierte alkalische phosphatase aus kälberdarm

Also Published As

Publication number Publication date
US6406899B1 (en) 2002-06-18
AU2692699A (en) 1999-11-11
DE19819962A1 (de) 1999-11-11
ZA993079B (en) 2000-11-06
EP0955369A3 (de) 2002-02-06
JP4295386B2 (ja) 2009-07-15
EP0955369B1 (de) 2006-04-19
DE59913343D1 (de) 2006-05-24
ATE323769T1 (de) 2006-05-15
EP0955369A2 (de) 1999-11-10
NZ335500A (en) 2000-02-28
JPH11332586A (ja) 1999-12-07

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