JP4189048B2 - 複素環化合物 - Google Patents

複素環化合物 Download PDF

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Publication number
JP4189048B2
JP4189048B2 JP36788797A JP36788797A JP4189048B2 JP 4189048 B2 JP4189048 B2 JP 4189048B2 JP 36788797 A JP36788797 A JP 36788797A JP 36788797 A JP36788797 A JP 36788797A JP 4189048 B2 JP4189048 B2 JP 4189048B2
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JP
Japan
Prior art keywords
group
carbon atoms
substituted
alkyl
same
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP36788797A
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English (en)
Japanese (ja)
Other versions
JPH11193282A (ja
JPH11193282A5 (enExample
Inventor
歩 栗本
哲広 荻野
肇 川上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Priority to JP36788797A priority Critical patent/JP4189048B2/ja
Publication of JPH11193282A publication Critical patent/JPH11193282A/ja
Publication of JPH11193282A5 publication Critical patent/JPH11193282A5/ja
Application granted granted Critical
Publication of JP4189048B2 publication Critical patent/JP4189048B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP36788797A 1997-12-26 1997-12-26 複素環化合物 Expired - Fee Related JP4189048B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP36788797A JP4189048B2 (ja) 1997-12-26 1997-12-26 複素環化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP36788797A JP4189048B2 (ja) 1997-12-26 1997-12-26 複素環化合物

Publications (3)

Publication Number Publication Date
JPH11193282A JPH11193282A (ja) 1999-07-21
JPH11193282A5 JPH11193282A5 (enExample) 2005-09-02
JP4189048B2 true JP4189048B2 (ja) 2008-12-03

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ID=18490454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP36788797A Expired - Fee Related JP4189048B2 (ja) 1997-12-26 1997-12-26 複素環化合物

Country Status (1)

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JP (1) JP4189048B2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60228229D1 (de) 2001-04-17 2008-09-25 Dainippon Sumitomo Pharma Co Neue adeninderivate
NZ539064A (en) 2002-09-27 2007-09-28 Dainippon Sumitomo Pharma Co Novel adenine compound and use thereof
WO2005025583A2 (en) * 2003-09-05 2005-03-24 Anadys Pharmaceuticals, Inc. Tlr7 ligands for the treatment of hepatitis c
TWI392678B (zh) 2004-03-26 2013-04-11 Dainippon Sumitomo Pharma Co 9-取代-8-氧基腺嘌呤化合物
ES2577514T3 (es) 2005-08-22 2016-07-15 The Regents Of The University Of California Antagonistas de TLR
MX2008010611A (es) 2006-02-17 2008-11-12 Pfizer Ltd Derivados de 3-desazapurina como moduladores de receptores similares a toll.
WO2008004948A1 (en) 2006-07-05 2008-01-10 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of tlr7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
EA019151B1 (ru) 2007-02-07 2014-01-30 Дзе Регентс Оф Дзе Юниверсити Оф Калифорния Конъюгаты синтетических агонистов tlr и их применение
EP2139894B1 (en) 2007-03-19 2011-10-26 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
WO2008114008A1 (en) 2007-03-19 2008-09-25 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators
AR065784A1 (es) * 2007-03-20 2009-07-01 Dainippon Sumitomo Pharma Co Derivados de 8-oxo adenina,medicamentos que los contienen y usos como agentes terapeuticos para enfermedades alergicas, antivirales o antibacterianas.
EP2138497A4 (en) 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co NEW ADENINE CONNECTION
JP5400763B2 (ja) 2007-05-08 2014-01-29 アストラゼネカ・アクチエボラーグ 免疫調節特性を有するイミダゾキノリン類
PE20091236A1 (es) 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
CN102143964A (zh) 2008-01-17 2011-08-03 大日本住友制药株式会社 制备腺嘌呤化合物的方法
WO2010088924A1 (en) 2009-02-06 2010-08-12 Telormedix Sa Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
CA2760766A1 (en) 2009-05-21 2010-11-25 Nicholas James Bennett Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
US8507507B2 (en) 2009-10-22 2013-08-13 Gilead Sciences, Inc. Modulators of toll-like receptors
US9050319B2 (en) 2010-04-30 2015-06-09 Telormedix, Sa Phospholipid drug analogs
CA2797315C (en) 2010-04-30 2018-09-11 Telormedix Sa Phospholipid drug analogs
WO2012080728A1 (en) 2010-12-16 2012-06-21 Astrazeneca Ab Imidazo [4, 5 -c] quinolin- 1 -yl derivative useful in therapy
US8895570B2 (en) 2010-12-17 2014-11-25 Astrazeneca Ab Purine derivatives
JP6184423B2 (ja) 2012-05-18 2017-08-23 大日本住友製薬株式会社 カルボン酸化合物
PL3294740T3 (pl) 2015-05-08 2020-03-31 F. Hoffmann-La Roche Ag Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych
US11697851B2 (en) 2016-05-24 2023-07-11 The Regents Of The University Of California Early ovarian cancer detection diagnostic test based on mRNA isoforms
AU2017320742B2 (en) * 2016-08-29 2021-08-05 F. Hoffmann-La Roche Ag 7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection
PL3512556T3 (pl) 2016-09-13 2021-12-27 F. Hoffmann-La Roche Ag Leczenie skojarzone agonistą TLR7 i inhibitorem składania kapsydu HBV
CN111699187A (zh) * 2018-02-12 2020-09-22 豪夫迈·罗氏有限公司 用于治疗和预防病毒感染的新的砜化合物和衍生物
WO2019166432A1 (en) 2018-02-28 2019-09-06 F. Hoffmann-La Roche Ag 7-substituted sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of liver cancer

Also Published As

Publication number Publication date
JPH11193282A (ja) 1999-07-21

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