JP4189048B2 - 複素環化合物 - Google Patents

複素環化合物 Download PDF

Info

Publication number
JP4189048B2
JP4189048B2 JP36788797A JP36788797A JP4189048B2 JP 4189048 B2 JP4189048 B2 JP 4189048B2 JP 36788797 A JP36788797 A JP 36788797A JP 36788797 A JP36788797 A JP 36788797A JP 4189048 B2 JP4189048 B2 JP 4189048B2
Authority
JP
Japan
Prior art keywords
group
carbon atoms
substituted
alkyl
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP36788797A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11193282A (ja
JPH11193282A5 (enExample
Inventor
歩 栗本
哲広 荻野
肇 川上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Priority to JP36788797A priority Critical patent/JP4189048B2/ja
Publication of JPH11193282A publication Critical patent/JPH11193282A/ja
Publication of JPH11193282A5 publication Critical patent/JPH11193282A5/ja
Application granted granted Critical
Publication of JP4189048B2 publication Critical patent/JP4189048B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP36788797A 1997-12-26 1997-12-26 複素環化合物 Expired - Fee Related JP4189048B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP36788797A JP4189048B2 (ja) 1997-12-26 1997-12-26 複素環化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP36788797A JP4189048B2 (ja) 1997-12-26 1997-12-26 複素環化合物

Publications (3)

Publication Number Publication Date
JPH11193282A JPH11193282A (ja) 1999-07-21
JPH11193282A5 JPH11193282A5 (enExample) 2005-09-02
JP4189048B2 true JP4189048B2 (ja) 2008-12-03

Family

ID=18490454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP36788797A Expired - Fee Related JP4189048B2 (ja) 1997-12-26 1997-12-26 複素環化合物

Country Status (1)

Country Link
JP (1) JP4189048B2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE404561T1 (de) * 2001-04-17 2008-08-15 Dainippon Sumitomo Pharma Co Neue adeninderivate
NZ539064A (en) 2002-09-27 2007-09-28 Dainippon Sumitomo Pharma Co Novel adenine compound and use thereof
GEP20084545B (en) * 2003-09-05 2008-11-25 Anadys Pharmaceuticals Inc Introducing tlr7 ligands and prodrugs thereof for the treatment of hepatitis c viral infection
TWI392678B (zh) 2004-03-26 2013-04-11 Dainippon Sumitomo Pharma Co ９-取代-８-氧基腺嘌呤化合物
CN101304748A (zh) * 2005-08-22 2008-11-12 加利福尼亚大学董事会 Tlr激动剂
JP2009528989A (ja) 2006-02-17 2009-08-13 ファイザー・リミテッド Ｔｌｒ７変調剤としての３−デアザプリン誘導体
JP2009542645A (ja) 2006-07-05 2009-12-03 アストラゼネカ・アクチエボラーグ Ｔｌｒ７のモジュレーターとして作用する８−オキソアデニン誘導体
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
ES2456964T3 (es) 2007-02-07 2014-04-24 The Regents Of The University Of California Conjugados de agonistas de TLR sintéticos y usos de los mismos
EP2132209B8 (en) 2007-03-19 2014-04-16 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators
EP2139894B1 (en) 2007-03-19 2011-10-26 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
WO2008114819A1 (ja) 2007-03-20 2008-09-25 Dainippon Sumitomo Pharma Co., Ltd. 新規アデニン化合物
PE20081887A1 (es) * 2007-03-20 2009-01-16 Dainippon Sumitomo Pharma Co Nuevo compuesto de adenina
DK2155743T3 (da) 2007-05-08 2012-11-05 Astrazeneca Ab Imidazoquinoliner med immunmodulerende egenskaber
PE20091236A1 (es) 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
CN102143964A (zh) 2008-01-17 2011-08-03 大日本住友制药株式会社 制备腺嘌呤化合物的方法
WO2010088924A1 (en) 2009-02-06 2010-08-12 Telormedix Sa Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
BRPI1010937A2 (pt) 2009-05-21 2019-09-24 Astrazeneca Ab composto, uso de um composto, e, método para tratar câncer
AU2010310813B2 (en) 2009-10-22 2015-06-18 Gilead Sciences, Inc. Derivatives of purine or deazapurine useful for the treatment of (inter alia) viral infections
US9050319B2 (en) 2010-04-30 2015-06-09 Telormedix, Sa Phospholipid drug analogs
KR20130056249A (ko) 2010-04-30 2013-05-29 텔로메딕스 에스에이 인지질 약물 유사체
WO2012080728A1 (en) 2010-12-16 2012-06-21 Astrazeneca Ab Imidazo [4, 5 -c] quinolin- 1 -yl derivative useful in therapy
US8895570B2 (en) 2010-12-17 2014-11-25 Astrazeneca Ab Purine derivatives
WO2013172479A1 (en) 2012-05-18 2013-11-21 Dainippon Sumitomo Pharma Co., Ltd. Carboxylic acid compounds
RS59435B1 (sr) * 2015-05-08 2019-11-29 Hoffmann La Roche Nova jedinjenja sulfonimidoil purinona i njihovi derivati za lečenje i profilaksu virusne infekcije
US11697851B2 (en) 2016-05-24 2023-07-11 The Regents Of The University Of California Early ovarian cancer detection diagnostic test based on mRNA isoforms
IL293475B2 (en) 2016-08-29 2024-10-01 Hoffmann La Roche 7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection
BR112019004560A2 (pt) 2016-09-13 2019-07-02 Hoffmann La Roche tratamento combinado com agonista de tlr7 e um inibidor de formação de capsídeo de hbv
EP3752505B1 (en) 2018-02-12 2023-01-11 F. Hoffmann-La Roche AG Novel sulfone compounds and derivatives for the treatment and prophylaxis of virus infection
BR112020016509A2 (pt) * 2018-02-28 2020-12-15 F. Hoffmann-La Roche Ag Composto, composto para uso no tratamento ou profilaxia do câncer de fígado, composição farmacêutica ou medicamento, uso e método para o tratamento ou profilaxia do câncer de fígado

Also Published As

Publication number Publication date
JPH11193282A (ja) 1999-07-21

Similar Documents

Publication Publication Date Title
JP4189048B2 (ja) 複素環化合物
JP4375901B2 (ja) 新規な複素環化合物
JP4497340B2 (ja) ピリミジン誘導体
JP5197539B2 (ja) ９置換−８−オキソアデニン化合物
JPWO1999028321A1 (ja) 新規な複素環化合物
JP3315983B2 (ja) １−置換 １Ｈ−イミダゾ（４，５−ｃ）キノリン−４−アミン，中間体及び医薬用組成物
RU2127734C1 (ru) Производные пиридопиримидина, их получение, фармацевтическая композиция, способ лечения
JPH11180981A (ja) 複素環誘導体
JP4890723B2 (ja) ＴＮＦαインヒビターとして有用なクマリン誘導体
JPWO2000012487A1 (ja) ピリミジン誘導体
JPWO2005092892A1 (ja) ８−オキソアデニン化合物
JP4342007B2 (ja) キナゾリン誘導体
JP4315300B2 (ja) 新規なキナゾリン誘導体
JPH08502721A (ja) 医薬的に活性な二環式‐複素環アミン
KR20000068421A (ko) 인다졸 유도체 및 포스포디에스터라제 (ｐｄｅ) 유형 ｉｖ 및 종양 괴사 인자 (ｔｎｆ) 생산의 억제제로서 그의 용도
US20070179149A1 (en) Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors
CN113549080B (zh) 一类1,2,3-三氮唑并嘧啶类化合物、其制备方法和用途
JPH11106340A (ja) Ｓｔａｔ６活性化阻害剤
JP4248245B2 (ja) ６−フェニルベンゾナフチリジン
JP5094725B2 (ja) Ｈｉｖインテグラーゼ阻害剤
JPWO2004002484A1 (ja) ホスホジエステラーゼ阻害剤
JP2000229959A (ja) Ｓｔａｔ６活性化阻害剤
CN115003300A (zh) Jak抑制剂
KR20060092220A (ko) 유도성 ｎｏ-신타아제 저해제로서의 이미다조피리딘 유도체
TW202402288A (zh) 用於治療急性炎症之嘧啶酮化合物

Legal Events

Date Code Title Description
A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20041111

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20041111

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20041111

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20041111

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050210

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20051026

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080617

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20080618

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080806

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20080902

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20080912

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110919

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees