JP4189048B2 - 複素環化合物 - Google Patents
複素環化合物 Download PDFInfo
- Publication number
- JP4189048B2 JP4189048B2 JP36788797A JP36788797A JP4189048B2 JP 4189048 B2 JP4189048 B2 JP 4189048B2 JP 36788797 A JP36788797 A JP 36788797A JP 36788797 A JP36788797 A JP 36788797A JP 4189048 B2 JP4189048 B2 JP 4189048B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- carbon atoms
- substituted
- alkyl
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 **c(nc1[n]2Cc3ccccc3)nc(N)c1nc2O Chemical compound **c(nc1[n]2Cc3ccccc3)nc(N)c1nc2O 0.000 description 3
- BQGDDAYSNFLDLH-UHFFFAOYSA-N CC(C)CSc1nc(N)c2nc[n](Cc3ccccc3)c2n1 Chemical compound CC(C)CSc1nc(N)c2nc[n](Cc3ccccc3)c2n1 BQGDDAYSNFLDLH-UHFFFAOYSA-N 0.000 description 1
- CTFPXLSBZGGGJG-UHFFFAOYSA-N CCCSc(nc1[n]2Cc3ccccc3)nc(N)c1nc2Br Chemical compound CCCSc(nc1[n]2Cc3ccccc3)nc(N)c1nc2Br CTFPXLSBZGGGJG-UHFFFAOYSA-N 0.000 description 1
- VGSBMDOWAWHTIU-UHFFFAOYSA-N CCSc(nc1N)nc([n]2Cc3ccccc3)c1nc2O Chemical compound CCSc(nc1N)nc([n]2Cc3ccccc3)c1nc2O VGSBMDOWAWHTIU-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36788797A JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36788797A JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11193282A JPH11193282A (ja) | 1999-07-21 |
| JPH11193282A5 JPH11193282A5 (enrdf_load_stackoverflow) | 2005-09-02 |
| JP4189048B2 true JP4189048B2 (ja) | 2008-12-03 |
Family
ID=18490454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP36788797A Expired - Fee Related JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4189048B2 (enrdf_load_stackoverflow) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE404561T1 (de) | 2001-04-17 | 2008-08-15 | Dainippon Sumitomo Pharma Co | Neue adeninderivate |
| US7754728B2 (en) | 2002-09-27 | 2010-07-13 | Dainippon Sumitomo Pharma Co., Ltd. | Adenine compound and use thereof |
| EP1667694B1 (en) * | 2003-09-05 | 2010-04-28 | Anadys Pharmaceuticals, Inc. | Tlr7 ligands for the treatment of hepatitis c |
| TWI414525B (zh) | 2004-03-26 | 2013-11-11 | Dainippon Sumitomo Pharma Co | 9-取代-8-氧基腺嘌呤化合物 |
| US20090324551A1 (en) * | 2005-08-22 | 2009-12-31 | The Regents Of The University Of California Office Of Technology Transfer | Tlr agonists |
| ES2374455T3 (es) | 2006-02-17 | 2012-02-16 | Pfizer Limited | Derivados de 3-deazapurinza como moduladores de tlr7. |
| US8138172B2 (en) | 2006-07-05 | 2012-03-20 | Astrazeneca Ab | 8-oxoadenine derivatives acting as modulators of TLR7 |
| TW200831105A (en) | 2006-12-14 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| SI2510946T1 (sl) | 2007-02-07 | 2015-12-31 | The Regents Of The University Of California | Konjugati sintetičnih agonistov TLR in njihove uporabe |
| US8063051B2 (en) | 2007-03-19 | 2011-11-22 | Astrazeneca Ab | 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7) modulators |
| US8067413B2 (en) | 2007-03-19 | 2011-11-29 | Astrazeneca Ab | 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators |
| AR065784A1 (es) * | 2007-03-20 | 2009-07-01 | Dainippon Sumitomo Pharma Co | Derivados de 8-oxo adenina,medicamentos que los contienen y usos como agentes terapeuticos para enfermedades alergicas, antivirales o antibacterianas. |
| US8044056B2 (en) | 2007-03-20 | 2011-10-25 | Dainippon Sumitomo Pharma Co., Ltd. | Adenine compound |
| ES2393037T3 (es) | 2007-05-08 | 2012-12-18 | Astrazeneca Ab | Imidazoquinolinas con propiedades inmunomoduladoras |
| PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| PE20091156A1 (es) | 2007-12-17 | 2009-09-03 | Astrazeneca Ab | Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo |
| CA2711769A1 (en) | 2008-01-17 | 2009-07-23 | Dainippon Sumitomo Pharma Co. Ltd. | Method for preparing adenine compound |
| WO2010088924A1 (en) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
| GB0908772D0 (en) | 2009-05-21 | 2009-07-01 | Astrazeneca Ab | New salts 756 |
| CA2760766A1 (en) | 2009-05-21 | 2010-11-25 | Nicholas James Bennett | Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases |
| ES2644286T3 (es) | 2009-10-22 | 2017-11-28 | Gilead Sciences, Inc. | Derivados de purina o deazapurina útiles para el tratamiento de (entre otros) infecciones víricas |
| EP2563404B1 (en) | 2010-04-30 | 2016-09-21 | Urogen Pharma Ltd. | Phospholipid drug analogs |
| US9050319B2 (en) | 2010-04-30 | 2015-06-09 | Telormedix, Sa | Phospholipid drug analogs |
| JP5978225B2 (ja) | 2010-12-16 | 2016-08-24 | 大日本住友製薬株式会社 | 治療に有用なイミダゾ[4,5−c]キノリン−1−イル誘導体 |
| DK2651943T3 (en) | 2010-12-17 | 2017-06-06 | Sumitomo Dainippon Pharma Co Ltd | purine derivatives |
| EP2850067B1 (en) | 2012-05-18 | 2017-08-16 | Sumitomo Dainippon Pharma Co., Ltd. | Carboxylic acid compounds |
| RS59435B1 (sr) * | 2015-05-08 | 2019-11-29 | Hoffmann La Roche | Nova jedinjenja sulfonimidoil purinona i njihovi derivati za lečenje i profilaksu virusne infekcije |
| US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
| AU2017320742B2 (en) * | 2016-08-29 | 2021-08-05 | F. Hoffmann-La Roche Ag | 7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection |
| BR112019004560A2 (pt) | 2016-09-13 | 2019-07-02 | Hoffmann La Roche | tratamento combinado com agonista de tlr7 e um inibidor de formação de capsídeo de hbv |
| CN111699187A (zh) * | 2018-02-12 | 2020-09-22 | 豪夫迈·罗氏有限公司 | 用于治疗和预防病毒感染的新的砜化合物和衍生物 |
| MX2020008746A (es) | 2018-02-28 | 2020-09-28 | Hoffmann La Roche | Compuestos de sulfonimidoilpurinona 7-sustituidos y sus derivados para el tratamiento y prevencion del cancer de higado. |
-
1997
- 1997-12-26 JP JP36788797A patent/JP4189048B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11193282A (ja) | 1999-07-21 |
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