JP4153999B2 - 経皮作用剤流量を強化するための組成物と方法 - Google Patents

経皮作用剤流量を強化するための組成物と方法 Download PDF

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Publication number
JP4153999B2
JP4153999B2 JP52890398A JP52890398A JP4153999B2 JP 4153999 B2 JP4153999 B2 JP 4153999B2 JP 52890398 A JP52890398 A JP 52890398A JP 52890398 A JP52890398 A JP 52890398A JP 4153999 B2 JP4153999 B2 JP 4153999B2
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Prior art keywords
agent
binding medium
body surface
skin
opening
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Expired - Fee Related
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JP52890398A
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Japanese (ja)
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JP2001506904A (ja
JP2001506904A5 (enExample
Inventor
ジーウウェス，フェリックス
ヌーカーマンズ，アーマンド・ピー
コーミア，マイケル・ジェイ・エヌ
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アルザ・コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body

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  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Surgical Instruments (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP52890398A 1996-12-20 1997-12-16 経皮作用剤流量を強化するための組成物と方法 Expired - Fee Related JP4153999B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3344096P 1996-12-20 1996-12-20
US60/033,440 1996-12-20
PCT/US1997/023274 WO1998028037A1 (en) 1996-12-20 1997-12-16 Device and method for enhancing transdermal agent flux

Publications (3)

Publication Number Publication Date
JP2001506904A JP2001506904A (ja) 2001-05-29
JP2001506904A5 JP2001506904A5 (enExample) 2005-06-16
JP4153999B2 true JP4153999B2 (ja) 2008-09-24

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP52890398A Expired - Fee Related JP4153999B2 (ja) 1996-12-20 1997-12-16 経皮作用剤流量を強化するための組成物と方法

Country Status (11)

Country Link
EP (1) EP0957972B1 (enExample)
JP (1) JP4153999B2 (enExample)
KR (1) KR100453132B1 (enExample)
CN (1) CN1133472C (enExample)
AT (1) ATE234649T1 (enExample)
AU (1) AU722574B2 (enExample)
CA (1) CA2271167C (enExample)
DE (1) DE69720057T2 (enExample)
DK (1) DK0957972T3 (enExample)
ES (1) ES2195190T3 (enExample)
WO (1) WO1998028037A1 (enExample)

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EP0957972B1 (en) 2003-03-19
DK0957972T3 (da) 2003-07-21
CN1233967A (zh) 1999-11-03
EP0957972A1 (en) 1999-11-24
AU722574B2 (en) 2000-08-10
DE69720057D1 (de) 2003-04-24
WO1998028037A1 (en) 1998-07-02
CN1133472C (zh) 2004-01-07
CA2271167C (en) 2007-01-09
CA2271167A1 (en) 1998-07-02
ATE234649T1 (de) 2003-04-15
KR20000053006A (ko) 2000-08-25
DE69720057T2 (de) 2003-09-25
ES2195190T3 (es) 2003-12-01
AU5529498A (en) 1998-07-17
JP2001506904A (ja) 2001-05-29
KR100453132B1 (ko) 2004-10-15

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