CA2271167C - Device and method for enhancing transdermal agent flux - Google Patents
Device and method for enhancing transdermal agent flux Download PDFInfo
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- CA2271167C CA2271167C CA002271167A CA2271167A CA2271167C CA 2271167 C CA2271167 C CA 2271167C CA 002271167 A CA002271167 A CA 002271167A CA 2271167 A CA2271167 A CA 2271167A CA 2271167 C CA2271167 C CA 2271167C
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B2010/008—Interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
- A61N1/303—Constructional details
- A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
Landscapes
- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Electrotherapy Devices (AREA)
- Surgical Instruments (AREA)
- Nonmetallic Welding Materials (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3344096P | 1996-12-20 | 1996-12-20 | |
| US60/033,440 | 1996-12-20 | ||
| PCT/US1997/023274 WO1998028037A1 (en) | 1996-12-20 | 1997-12-16 | Device and method for enhancing transdermal agent flux |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2271167A1 CA2271167A1 (en) | 1998-07-02 |
| CA2271167C true CA2271167C (en) | 2007-01-09 |
Family
ID=21870407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002271167A Expired - Fee Related CA2271167C (en) | 1996-12-20 | 1997-12-16 | Device and method for enhancing transdermal agent flux |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0957972B1 (enExample) |
| JP (1) | JP4153999B2 (enExample) |
| KR (1) | KR100453132B1 (enExample) |
| CN (1) | CN1133472C (enExample) |
| AT (1) | ATE234649T1 (enExample) |
| AU (1) | AU722574B2 (enExample) |
| CA (1) | CA2271167C (enExample) |
| DE (1) | DE69720057T2 (enExample) |
| DK (1) | DK0957972T3 (enExample) |
| ES (1) | ES2195190T3 (enExample) |
| WO (1) | WO1998028037A1 (enExample) |
Families Citing this family (132)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3316820B2 (ja) | 1995-12-28 | 2002-08-19 | シィグナス インコーポレィティド | 被験者の生理的分析物の継続モニタリング装置及び方法 |
| EP1911488A3 (en) | 1997-12-11 | 2008-12-03 | Alza Corporation | Device for enhancing transdermal agent flux |
| WO1999029365A1 (en) | 1997-12-11 | 1999-06-17 | Alza Corporation | Device for enhancing transdermal agent flux |
| DE69839969D1 (de) | 1997-12-11 | 2008-10-16 | Alza Corp | Vorrichtung zur verbesserung des transdermalen flusses von medikamenten |
| US7066884B2 (en) | 1998-01-08 | 2006-06-27 | Sontra Medical, Inc. | System, method, and device for non-invasive body fluid sampling and analysis |
| US7344499B1 (en) | 1998-06-10 | 2008-03-18 | Georgia Tech Research Corporation | Microneedle device for extraction and sensing of bodily fluids |
| US6503231B1 (en) | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| CA2341446C (en) * | 1998-08-31 | 2008-10-07 | Johnson & Johnson Consumer Companies, Inc. | Electrotransport device comprising blades |
| US20040171980A1 (en) | 1998-12-18 | 2004-09-02 | Sontra Medical, Inc. | Method and apparatus for enhancement of transdermal transport |
| US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
| TR200103018T2 (tr) | 1999-04-19 | 2002-02-21 | Beecham Biologicals S.A. Smithkline | İmmünostimülatör oligonükleotid ve saponin içeren katkı bileşikleri. |
| AU5461300A (en) * | 1999-06-04 | 2000-12-28 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6611707B1 (en) | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
| US6743211B1 (en) | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| EP1189660B1 (en) * | 1999-06-08 | 2006-05-03 | Altea Therapeutics Corporation | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor |
| US20040039342A1 (en) * | 2000-06-08 | 2004-02-26 | Jonathan Eppstein | Transdermal integrated actuator device, methods of making and using same |
| US6890553B1 (en) | 1999-07-08 | 2005-05-10 | Johnson & Johnson Consumer Companies, Inc. | Exothermic topical delivery device |
| AU6076200A (en) | 1999-07-08 | 2001-01-30 | Johnson & Johnson Consumer Companies, Inc. | Exothermic bandage |
| US7133717B2 (en) | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
| US7113821B1 (en) | 1999-08-25 | 2006-09-26 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery |
| WO2001041863A1 (en) | 1999-12-10 | 2001-06-14 | Alza Corporation | Device and method for enhancing microprotrusion skin piercing |
| KR100832754B1 (ko) * | 1999-12-10 | 2008-05-27 | 알자 코포레이션 | 지속성 경피약물 송출용 피부치료장치 |
| US6622035B1 (en) * | 2000-01-21 | 2003-09-16 | Instrumentarium Corp. | Electrode for measurement of weak bioelectrical signals |
| US7404815B2 (en) | 2000-05-01 | 2008-07-29 | Lifescan, Inc. | Tissue ablation by shear force for sampling biological fluids and delivering active agents |
| US6749575B2 (en) | 2001-08-20 | 2004-06-15 | Alza Corporation | Method for transdermal nucleic acid sampling |
| AU8346901A (en) * | 2000-08-24 | 2002-03-04 | Alza Corp | Method for transdermal nucleic acid sampling |
| NZ524646A (en) | 2000-09-08 | 2004-10-29 | Alza Corp | Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| RU2275871C2 (ru) * | 2000-10-13 | 2006-05-10 | Алза Корпорейшн | Устройство и способ для прокалывания кожи микровыступами |
| US7419481B2 (en) | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
| US6855131B2 (en) * | 2000-10-13 | 2005-02-15 | Alza Corporation | Microprotrusion member retainer for impact applicator |
| EP1341442B1 (en) * | 2000-10-13 | 2005-06-29 | Alza Corporation | Microblade array impact applicator |
| US7108681B2 (en) * | 2000-10-16 | 2006-09-19 | Corium International, Inc. | Microstructures for delivering a composition cutaneously to skin |
| SI2266603T1 (sl) | 2000-10-18 | 2012-12-31 | Glaxosmithkline Biologicals S.A. | Tumorska cepiva |
| BR0114909A (pt) | 2000-10-26 | 2004-02-03 | Alza Corp | Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas |
| WO2002064193A2 (en) | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
| WO2002050584A2 (en) | 2000-12-21 | 2002-06-27 | Biovalve Technologies, Inc. | Microneedle array systems |
| US6855372B2 (en) | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
| ES2333849T3 (es) | 2001-04-20 | 2010-03-02 | Alza Corporation | Disposicion de microsalientes que presenta un revestimiento que contiene un agente beneficioso. |
| EP3251722B1 (en) | 2001-04-20 | 2020-06-17 | ALZA Corporation | Microprojection array having a beneficial agent containing coating and method of forming the coating thereon |
| US8361037B2 (en) | 2001-09-19 | 2013-01-29 | Valeritas, Inc. | Microneedles, microneedle arrays, and systems and methods relating to same |
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|---|---|---|---|---|
| US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
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| DE19525607A1 (de) * | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
-
1997
- 1997-12-16 DK DK97951729T patent/DK0957972T3/da active
- 1997-12-16 AT AT97951729T patent/ATE234649T1/de not_active IP Right Cessation
- 1997-12-16 AU AU55294/98A patent/AU722574B2/en not_active Ceased
- 1997-12-16 CA CA002271167A patent/CA2271167C/en not_active Expired - Fee Related
- 1997-12-16 DE DE69720057T patent/DE69720057T2/de not_active Expired - Lifetime
- 1997-12-16 WO PCT/US1997/023274 patent/WO1998028037A1/en not_active Ceased
- 1997-12-16 ES ES97951729T patent/ES2195190T3/es not_active Expired - Lifetime
- 1997-12-16 JP JP52890398A patent/JP4153999B2/ja not_active Expired - Fee Related
- 1997-12-16 CN CNB971990158A patent/CN1133472C/zh not_active Expired - Fee Related
- 1997-12-16 KR KR10-1999-7003888A patent/KR100453132B1/ko not_active Expired - Fee Related
- 1997-12-16 EP EP97951729A patent/EP0957972B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69720057T2 (de) | 2003-09-25 |
| WO1998028037A1 (en) | 1998-07-02 |
| DE69720057D1 (de) | 2003-04-24 |
| AU722574B2 (en) | 2000-08-10 |
| EP0957972B1 (en) | 2003-03-19 |
| ES2195190T3 (es) | 2003-12-01 |
| KR20000053006A (ko) | 2000-08-25 |
| JP2001506904A (ja) | 2001-05-29 |
| KR100453132B1 (ko) | 2004-10-15 |
| CA2271167A1 (en) | 1998-07-02 |
| DK0957972T3 (da) | 2003-07-21 |
| JP4153999B2 (ja) | 2008-09-24 |
| CN1233967A (zh) | 1999-11-03 |
| EP0957972A1 (en) | 1999-11-24 |
| CN1133472C (zh) | 2004-01-07 |
| AU5529498A (en) | 1998-07-17 |
| ATE234649T1 (de) | 2003-04-15 |
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