JP4050329B2 - プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 - Google Patents

プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 Download PDF

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JP4050329B2
JP4050329B2 JP54941398A JP54941398A JP4050329B2 JP 4050329 B2 JP4050329 B2 JP 4050329B2 JP 54941398 A JP54941398 A JP 54941398A JP 54941398 A JP54941398 A JP 54941398A JP 4050329 B2 JP4050329 B2 JP 4050329B2
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polypeptide
nucleic acid
acid sequence
seq
sequence
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JP2002511746A (ja
JP2002511746A5 (https=
Inventor
ブリンコフスキー，アレキサンダー
ブラウン，キンバリー
ダブリュ． レイ，マイケル
クロッツ，アラン
バイアン，トニー
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ノボザイムス，インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24—Organic nitrogen compounds
    • A21D2/26—Proteins
    • A21D2/267—Microbial proteins
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/21—Synthetic spices, flavouring agents or condiments containing amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP54941398A 1997-05-16 1998-05-12 プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 Expired - Fee Related JP4050329B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US85788497A 1997-05-16 1997-05-16
US08/857,884 1997-05-16
US6289297P 1997-10-20 1997-10-20
US60/062,892 1997-10-20
PCT/US1998/009629 WO1998051803A1 (en) 1997-05-16 1998-05-12 Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same

Publications (3)

Publication Number Publication Date
JP2002511746A JP2002511746A (ja) 2002-04-16
JP2002511746A5 JP2002511746A5 (https=) 2005-12-08
JP4050329B2 true JP4050329B2 (ja) 2008-02-20

Family

ID=26742833

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54941398A Expired - Fee Related JP4050329B2 (ja) 1997-05-16 1998-05-12 プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸

Country Status (9)

Country Link
US (2) US6664092B1 (https=)
EP (1) EP0981630B1 (https=)
JP (1) JP4050329B2 (https=)
CN (1) CN1227363C (https=)
AT (1) ATE414775T1 (https=)
AU (1) AU7381098A (https=)
DE (1) DE69840230D1 (https=)
DK (1) DK0981630T3 (https=)
WO (1) WO1998051803A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3727780B2 (ja) * 1998-06-12 2005-12-14 キッコーマン株式会社 ロイシンアミノペプチダーゼ遺伝子、組み換え体ｄｎａ及びロイシンアミノペプチダーゼの製造法
WO2002077223A1 (fr) 2001-03-19 2002-10-03 Ajinomoto Co.,Inc. Nouvelle aminopeptidase et son gene
US7186540B2 (en) * 2001-12-27 2007-03-06 National Institute of Advanced Indusrtial Science and Technology Thermostable glutaminase and thermostable glutaminase gene
ES2540926T3 (es) * 2002-06-04 2015-07-14 Dsm Ip Assets B.V. Hidrolizado de proteínas rico en tripéptidos
JP4300289B2 (ja) * 2002-08-27 2009-07-22 国立大学法人 岡山大学 加水分解又は脱水縮合酵素、及び当該酵素の生産方法、並びに当該酵素を用いたアミドの合成方法
CA2518465A1 (en) 2003-03-25 2004-10-14 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
JP2007511467A (ja) 2003-05-14 2007-05-10 タケダ サン ディエゴ インコーポレイテッド ジペプチジルペプチダーゼインヒビター
UA89616C2 (ru) 2003-08-01 2010-02-25 Калпис Ко., Лтд. Гидролизат казеина, способ его получения и применения
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
KR20060041309A (ko) 2003-08-13 2006-05-11 다케다 야쿠힌 고교 가부시키가이샤 ４-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1699777B1 (en) 2003-09-08 2012-12-12 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
UA85871C2 (uk) 2004-03-15 2009-03-10 Такеда Фармасьютікал Компані Лімітед Інгібітори дипептидилпептидази
US7687638B2 (en) 2004-06-04 2010-03-30 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
JP2008524331A (ja) 2004-12-21 2008-07-10 武田薬品工業株式会社 ジペプチジルペプチダーゼ阻害剤
MY147393A (en) 2005-09-14 2012-11-30 Takeda Pharmaceutical Administration of dipeptidyl peptidase inhibitors
CA2622642C (en) 2005-09-16 2013-12-31 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
ES2401965T3 (es) * 2009-02-19 2013-04-25 Novo Nordisk A/S Modificación de Factor VIII
JP5759132B2 (ja) * 2010-09-21 2015-08-05 月桂冠株式会社 糸状菌ペプチダーゼの生産方法
WO2013092731A1 (en) * 2011-12-21 2013-06-27 Dsm Ip Assets B.V. Method for making a dough with a glutamyl endopeptidase
CN103695361B (zh) * 2013-12-06 2015-11-11 江南大学 一种生产脯氨酸氨肽酶的基因工程菌及其构建方法
GB201705750D0 (en) * 2017-04-10 2017-05-24 Univ Oxford Innovation Ltd Peptide ligase and use therof
EP4273249A3 (en) * 2023-07-07 2024-05-22 Novozymes A/S Improved expression of recombinant proteins

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857967A (en) 1971-05-10 1974-12-31 Kikkoman Shoyu Co Ltd Preparation of food and beverages with peptidoglutaminase
US4288627A (en) 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
JPS61279528A (ja) 1985-06-05 1986-12-10 Hokkai Can Co Ltd 容器の製造方法
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
JPH0665280B2 (ja) 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
JPS6450382A (en) 1987-08-20 1989-02-27 Hitachi Heating Appl Plane-form heating body
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
NL194258C (nl) * 1989-09-01 2001-11-05 Protein Technologies Internat Werkwijze voor het behandelen van een eiwithoudend materiaal.
DE69112611T2 (de) 1990-03-09 1996-03-14 Novonordisk As Proteinhydrolysate.
DK0531372T4 (da) 1990-05-09 2004-08-09 Novozymes As Cellulasepræparat omfattende et endoglucanaseenzym
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
DE69333718T2 (de) 1992-01-14 2005-12-01 Ajinomoto Co., Inc. Gen, das für eine Fisch-Transglutaminase kodiert
FI943458A7 (fi) 1992-01-22 1994-09-21 Novo Nordisk As Aktivoitu tekijä XIII
CN1057127C (zh) * 1993-04-23 2000-10-04 北京大学 固定化复合外肽酶蛋白质全水解及脱苦方法
DK46793D0 (da) 1993-04-26 1993-04-26 Novo Nordisk As Enzym
DK52393D0 (https=) 1993-05-05 1993-05-05 Novo Nordisk As
DK52293D0 (https=) 1993-05-05 1993-05-05 Novo Nordisk As
JPH07115969A (ja) * 1993-10-25 1995-05-09 Asahi Chem Ind Co Ltd 加水分解蛋白質の製造方法
FI964808A0 (fi) 1994-06-03 1996-12-02 Novo Nordisk Biotech Inc Puhdistetut Myceliophthora lakkaasit ja niitä koodaavat nukleiinihapot
CN101659926A (zh) 1994-06-30 2010-03-03 诺沃奇梅兹有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
NZ291414A (en) 1994-08-26 1998-05-27 Novo Nordisk As Microbial transglutaminases and methods of production using fungi and dna constructs
CA2208730A1 (en) 1995-01-19 1996-07-25 Novo Nordisk A/S Transglutaminases from oomycetes
DE69632630T2 (de) 1995-03-16 2005-05-25 Novozymes A/S Enzym mit aminopeptidaseactivität
JP2000515003A (ja) * 1996-05-20 2000-11-14 ノボ ノルディスク アクティーゼルスカブ タンパク質加水分解物を得る方法

Also Published As

Publication number Publication date
AU7381098A (en) 1998-12-08
JP2002511746A (ja) 2002-04-16
EP0981630A1 (en) 2000-03-01
DE69840230D1 (de) 2009-01-02
US6664092B1 (en) 2003-12-16
US7098001B2 (en) 2006-08-29
ATE414775T1 (de) 2008-12-15
CN1227363C (zh) 2005-11-16
WO1998051803A1 (en) 1998-11-19
EP0981630B1 (en) 2008-11-19
CN1268976A (zh) 2000-10-04
DK0981630T3 (da) 2009-03-09
US20040171104A1 (en) 2004-09-02

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